9 items (Sus scrofa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

co-expression

protein homology

Your Input:
	AGT	Angiotensinogen; Belongs to the serpin family. (482 aa)
	LMLN	Leishmanolysin-like peptidase. (694 aa)
	SLC12A8	Solute carrier family 12 member 8. (715 aa)
	MUC13	Uncharacterized protein. (537 aa)
	TFRC	Transferrin receptor protein 1; Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). Positively regulates T and B cell proliferation through iron uptake (By similarity). (794 aa)
	MUC20	Uncharacterized protein. (599 aa)
	GAPDH	Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] (398 aa)
	ITGB5	Integrin beta; Belongs to the integrin beta chain family. (800 aa)
	MUC4	Uncharacterized protein. (1173 aa)

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGT	GAPDH	ENSSSCP00000029872	ENSSSCP00000035519	Angiotensinogen; Belongs to the serpin family.	Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...]	0.436
GAPDH	AGT	ENSSSCP00000035519	ENSSSCP00000029872	Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...]	Angiotensinogen; Belongs to the serpin family.	0.436
GAPDH	TFRC	ENSSSCP00000035519	ENSSSCP00000029501	Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...]	Transferrin receptor protein 1; Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). Positively regulates T and B cell proliferation through iron uptake (By similarity).	0.710
ITGB5	MUC13	ENSSSCP00000049436	ENSSSCP00000012633	Integrin beta; Belongs to the integrin beta chain family.	Uncharacterized protein.	0.526
ITGB5	MUC20	ENSSSCP00000049436	ENSSSCP00000033626	Integrin beta; Belongs to the integrin beta chain family.	Uncharacterized protein.	0.418
ITGB5	SLC12A8	ENSSSCP00000049436	ENSSSCP00000012632	Integrin beta; Belongs to the integrin beta chain family.	Solute carrier family 12 member 8.	0.457
MUC13	ITGB5	ENSSSCP00000012633	ENSSSCP00000049436	Uncharacterized protein.	Integrin beta; Belongs to the integrin beta chain family.	0.526
MUC13	MUC20	ENSSSCP00000012633	ENSSSCP00000033626	Uncharacterized protein.	Uncharacterized protein.	0.952
MUC13	MUC4	ENSSSCP00000012633	ENSSSCP00000051590	Uncharacterized protein.	Uncharacterized protein.	0.956
MUC13	SLC12A8	ENSSSCP00000012633	ENSSSCP00000012632	Uncharacterized protein.	Solute carrier family 12 member 8.	0.695
MUC13	TFRC	ENSSSCP00000012633	ENSSSCP00000029501	Uncharacterized protein.	Transferrin receptor protein 1; Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). Positively regulates T and B cell proliferation through iron uptake (By similarity).	0.431
MUC20	ITGB5	ENSSSCP00000033626	ENSSSCP00000049436	Uncharacterized protein.	Integrin beta; Belongs to the integrin beta chain family.	0.418
MUC20	MUC13	ENSSSCP00000033626	ENSSSCP00000012633	Uncharacterized protein.	Uncharacterized protein.	0.952
MUC20	MUC4	ENSSSCP00000033626	ENSSSCP00000051590	Uncharacterized protein.	Uncharacterized protein.	0.968
MUC20	SLC12A8	ENSSSCP00000033626	ENSSSCP00000012632	Uncharacterized protein.	Solute carrier family 12 member 8.	0.677
MUC20	TFRC	ENSSSCP00000033626	ENSSSCP00000029501	Uncharacterized protein.	Transferrin receptor protein 1; Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). Positively regulates T and B cell proliferation through iron uptake (By similarity).	0.454
MUC4	MUC13	ENSSSCP00000051590	ENSSSCP00000012633	Uncharacterized protein.	Uncharacterized protein.	0.956
MUC4	MUC20	ENSSSCP00000051590	ENSSSCP00000033626	Uncharacterized protein.	Uncharacterized protein.	0.968
MUC4	SLC12A8	ENSSSCP00000051590	ENSSSCP00000012632	Uncharacterized protein.	Solute carrier family 12 member 8.	0.600
MUC4	TFRC	ENSSSCP00000051590	ENSSSCP00000029501	Uncharacterized protein.	Transferrin receptor protein 1; Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). Positively regulates T and B cell proliferation through iron uptake (By similarity).	0.405