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BMP8B | TGF_BETA_2 domain-containing protein. (401 aa) | ||||
FGF21 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) | ||||
PPARA | Uncharacterized protein. (469 aa) | ||||
FGF20 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa) | ||||
BMP4 | Bone morphogenetic protein 4. (409 aa) | ||||
BMP7 | Bone morphogenetic protein 7. (650 aa) | ||||
CIDEA | CIDE-N domain-containing protein. (376 aa) | ||||
FGF14 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (252 aa) | ||||
FGF13 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (255 aa) | ||||
FGF8 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa) | ||||
PDK4 | Protein-serine/threonine kinase. (411 aa) | ||||
TGM2 | Transglutaminase 2. (696 aa) | ||||
PRLR | Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin. (624 aa) | ||||
FGF9 | Fibroblast growth factor 9; Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. May have a role in glial cell growth and differentiation during development, gliosis during repair and regeneration of brain tissue after damage, differentiation and survival of neuronal cells, and growth stimulation of glial tumors (By similarity). (228 aa) | ||||
LEP | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways (By similarity). In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, inc [...] (192 aa) | ||||
FGF22 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (170 aa) | ||||
FGF2 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (316 aa) | ||||
FGF19 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (219 aa) | ||||
FGF12 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (328 aa) | ||||
UCP3 | Mitochondrial uncoupling protein 3; UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation. As a result, energy is dissipated in the form of heat. May play a role in the modulation of tissue respiratory control. Participates in thermogenesis and energy balance (By similarity); Belongs to the mitochondrial carrier (TC 2.A.29) family. (310 aa) | ||||
HOXC9 | Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (260 aa) | ||||
ADIPOQ | C1q domain-containing protein. (332 aa) | ||||
CEBPB | CCAAT/enhancer-binding protein. (346 aa) | ||||
INS | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (108 aa) | ||||
SERTAD2 | SERTA domain containing 2. (312 aa) | ||||
FGF6 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) | ||||
FGF5 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (271 aa) | ||||
KCNK3 | Potassium channel subfamily K member. (401 aa) | ||||
PRL | Prolactin; Prolactin acts primarily on the mammary gland by promoting lactation. (229 aa) | ||||
PPARGC1A | Peroxisome proliferator-activated receptor gamma coactivator 1-alpha; Transcriptional coactivator for steroid receptors and nuclear receptors. Greatly increases the transcriptional activity of PPARG and thyroid hormone receptor on the uncoupling protein promoter. Can regulate key mitochondrial genes that contribute to the program of adaptive thermogenesis. Plays an essential role in metabolic reprogramming in response to dietary availability through coordination of the expression of a wide array of genes involved in glucose and fatty acid metabolism. Induces the expression of PERM1 in [...] (796 aa) | ||||
FGF18 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (251 aa) | ||||
FGF16 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa) | ||||
MED13 | Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (2173 aa) | ||||
FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa) | ||||
MSTN | Growth/differentiation factor 8; Acts specifically as a negative regulator of skeletal muscle growth; Belongs to the TGF-beta family. (375 aa) | ||||
ADRB3 | Beta-3 adrenergic receptor; Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. Beta- 3 is involved in the regulation of lipolysis and thermogenesis; Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB3 sub-subfamily. (407 aa) | ||||
UCP2 | Mitochondrial uncoupling protein 2; UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat (By similarity). (308 aa) | ||||
FGF3 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (232 aa) | ||||
FGF4 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa) | ||||
PPARG | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (528 aa) | ||||
PTEN | Uncharacterized protein. (576 aa) | ||||
FGF17 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (215 aa) |