STRINGSTRING
DERA DERA CAPN3 CAPN3 LRIG2 LRIG2 THRA THRA PDZRN4 PDZRN4 STK32B STK32B DNAH3-2 DNAH3-2 LCORL LCORL WNT6 WNT6 SLC16A1 SLC16A1 TMEM154 TMEM154 IL1RL1 IL1RL1 ALDOA ALDOA SLC8A3 SLC8A3 SOCS3 SOCS3 MICAL3 MICAL3 PLCE1 PLCE1 ACACA ACACA FTO FTO TRHR TRHR EIF3F EIF3F ATP2A1 ATP2A1 INS INS RALY RALY TRIOBP TRIOBP EEFSEC EEFSEC APOBR APOBR TECRL TECRL RPL7 RPL7 DNAH3 DNAH3 SPTAN1 SPTAN1 SLC27A6 SLC27A6 RPGRIP1L RPGRIP1L EXOC6B EXOC6B PRKAA1 PRKAA1 BMPR1B BMPR1B WNT10A WNT10A EIF2S2 EIF2S2 NF1 NF1 PSMD3 PSMD3 PRKAG3 PRKAG3 MPZL3 MPZL3 PDGFD PDGFD GDF9 GDF9 INSR INSR SUFU SUFU PDS5B PDS5B HERC3 HERC3 NCAPG NCAPG EDAR EDAR PHKG1 PHKG1 TMC2 TMC2 RPS6 RPS6 TYRO3 TYRO3 SPTBN5 SPTBN5 CCNB2 CCNB2 CIB2 CIB2 PPP1R11 PPP1R11 CRADD CRADD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DERADeoxyribose-phosphate aldolase isoform X1. (318 aa)
CAPN3Calpain-3; Calcium-regulated non-lysosomal thiol-protease; Belongs to the peptidase C2 family. (830 aa)
LRIG2Leucine rich repeats and immunoglobulin like domains 2. (1065 aa)
THRAThyroid hormone receptor alpha; Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine. (508 aa)
PDZRN4PDZ domain containing ring finger 4. (1042 aa)
STK32BSerine/threonine kinase 32B; Belongs to the protein kinase superfamily. (428 aa)
DNAH3-2Uncharacterized protein. (668 aa)
LCORLUncharacterized protein. (1865 aa)
WNT6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (364 aa)
SLC16A1Solute carrier family 16, member 1 (Monocarboxylic acid transporter 1) tv1. (501 aa)
TMEM154Transmembrane protein 154. (192 aa)
IL1RL1Interleukin 1 receptor like 1. (573 aa)
ALDOAFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (532 aa)
SLC8A3Sodium/calcium exchanger 3 isoform A; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (928 aa)
SOCS3Suppressor of cytokine signaling 3. (229 aa)
MICAL3Microtubule associated monooxygenase, calponin and LIM domain containing 3. (2098 aa)
PLCE1Phosphoinositide phospholipase C. (2316 aa)
ACACAAcetyl-CoA carboxylase alpha. (2383 aa)
FTOFTO_NTD domain-containing protein. (509 aa)
TRHRThyrotropin-releasing hormone receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (398 aa)
EIF3FEukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (348 aa)
ATP2A1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1021 aa)
INSInsulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (108 aa)
RALYRALY heterogeneous nuclear ribonucleoprotein. (365 aa)
TRIOBPTRIO and F-actin binding protein. (2043 aa)
EEFSECEukaryotic elongation factor, selenocysteine-tRNA specific. (646 aa)
APOBRUncharacterized protein. (1283 aa)
TECRLTrans-2,3-enoyl-CoA reductase-like. (363 aa)
RPL7Uncharacterized protein. (249 aa)
DNAH3AAA_6 domain-containing protein. (308 aa)
SPTAN1Spectrin alpha, non-erythrocytic 1. (2390 aa)
SLC27A6Solute carrier family 27 member 6. (655 aa)
RPGRIP1LProtein fantom isoform X1. (1270 aa)
EXOC6BExocyst complex component; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (814 aa)
PRKAA1Non-specific serine/threonine protein kinase. (559 aa)
BMPR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
WNT10AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (415 aa)
EIF2S2Eukaryotic translation initiation factor 2 subunit beta. (333 aa)
NF1Neurofibromin 1. (2847 aa)
PSMD326S proteasome non-ATPase regulatory subunit 3. (534 aa)
PRKAG35'-AMP-activated protein kinase subunit gamma-3; AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a [...] (499 aa)
MPZL3Myelin protein zero like 3. (237 aa)
PDGFDPlatelet derived growth factor D; Belongs to the PDGF/VEGF growth factor family. (387 aa)
GDF9Growth differentiation factor 9. (444 aa)
INSRTyrosine-protein kinase receptor. (1382 aa)
SUFUSUFU negative regulator of hedgehog signaling. (432 aa)
PDS5BPDS5 cohesin associated factor B. (1575 aa)
HERC3Uncharacterized protein. (1050 aa)
NCAPGNon-SMC condensin I complex subunit G. (1034 aa)
EDAREctodysplasin A receptor. (461 aa)
PHKG1Phosphorylase kinase gamma 1; Belongs to the protein kinase superfamily. (388 aa)
TMC2Transmembrane channel-like protein. (904 aa)
RPS640S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (249 aa)
TYRO3TYRO3 protein tyrosine kinase. (913 aa)
SPTBN5Spectrin beta, non-erythrocytic 5. (3616 aa)
CCNB2G2/mitotic-specific cyclin-B2; Belongs to the cyclin family. (396 aa)
CIB2Calcium and integrin binding family member 2. (186 aa)
PPP1R11Protein phosphatase 1 regulatory inhibitor subunit 11. (126 aa)
CRADDCASP2 and RIPK1 domain containing adaptor with death domain. (237 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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