6 items (Sus scrofa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	INS	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (108 aa)
	IGF2R	Insulin-like growth factor II receptor. (2488 aa)
	IGF1R	Tyrosine-protein kinase receptor. (1367 aa)
	IGFBP7	Uncharacterized protein. (278 aa)
	INSIG1	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (308 aa)
	IRS1	Insulin receptor substrate 1. (1241 aa)

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
IGF1R	IGF2R	ENSSSCP00000005181	ENSSSCP00000004370	Tyrosine-protein kinase receptor.	Insulin-like growth factor II receptor.	0.918
IGF1R	IGFBP7	ENSSSCP00000005181	ENSSSCP00000009507	Tyrosine-protein kinase receptor.	Uncharacterized protein.	0.548
IGF1R	INS	ENSSSCP00000005181	ENSSSCP00000044635	Tyrosine-protein kinase receptor.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.998
IGF1R	INSIG1	ENSSSCP00000005181	ENSSSCP00000036426	Tyrosine-protein kinase receptor.	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.	0.420
IGF1R	IRS1	ENSSSCP00000005181	ENSSSCP00000061240	Tyrosine-protein kinase receptor.	Insulin receptor substrate 1.	0.988
IGF2R	IGF1R	ENSSSCP00000004370	ENSSSCP00000005181	Insulin-like growth factor II receptor.	Tyrosine-protein kinase receptor.	0.918
IGF2R	IGFBP7	ENSSSCP00000004370	ENSSSCP00000009507	Insulin-like growth factor II receptor.	Uncharacterized protein.	0.402
IGF2R	INS	ENSSSCP00000004370	ENSSSCP00000044635	Insulin-like growth factor II receptor.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.695
IGFBP7	IGF1R	ENSSSCP00000009507	ENSSSCP00000005181	Uncharacterized protein.	Tyrosine-protein kinase receptor.	0.548
IGFBP7	IGF2R	ENSSSCP00000009507	ENSSSCP00000004370	Uncharacterized protein.	Insulin-like growth factor II receptor.	0.402
IGFBP7	INS	ENSSSCP00000009507	ENSSSCP00000044635	Uncharacterized protein.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.615
INS	IGF1R	ENSSSCP00000044635	ENSSSCP00000005181	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Tyrosine-protein kinase receptor.	0.998
INS	IGF2R	ENSSSCP00000044635	ENSSSCP00000004370	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Insulin-like growth factor II receptor.	0.695
INS	IGFBP7	ENSSSCP00000044635	ENSSSCP00000009507	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Uncharacterized protein.	0.615
INS	INSIG1	ENSSSCP00000044635	ENSSSCP00000036426	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.	0.456
INS	IRS1	ENSSSCP00000044635	ENSSSCP00000061240	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Insulin receptor substrate 1.	0.986
INSIG1	IGF1R	ENSSSCP00000036426	ENSSSCP00000005181	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.	Tyrosine-protein kinase receptor.	0.420
INSIG1	INS	ENSSSCP00000036426	ENSSSCP00000044635	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.456
IRS1	IGF1R	ENSSSCP00000061240	ENSSSCP00000005181	Insulin receptor substrate 1.	Tyrosine-protein kinase receptor.	0.988
IRS1	INS	ENSSSCP00000061240	ENSSSCP00000044635	Insulin receptor substrate 1.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.986