25 items (Sus scrofa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CD109	CD109 antigen isoform 1 preproprotein. (1449 aa)
	ITGA5	Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1057 aa)
	RPE65	Retinoid isomerohydrolase RPE65. (533 aa)
	TYRP1	5,6-dihydroxyindole-2-carboxylic acid oxidase. (562 aa)
	AMTN	Amelotin. (209 aa)
	PTPRG	Protein tyrosine phosphatase receptor type G. (1452 aa)
	PXDN	Peroxidasin. (1529 aa)
	BEST1	Bestrophin-1; Forms calcium-sensitive chloride channels. Permeable to bicarbonate (By similarity); Belongs to the bestrophin family. (579 aa)
	NAV3	Neuron navigator 3. (2383 aa)
	TYR	Tyrosinase. (531 aa)
	SFRP1	Secreted frizzled-related protein 1. (308 aa)
	PAK1IP1	PAK1 interacting protein 1. (370 aa)
	ITGAV	Integrin subunit alpha V; Belongs to the integrin alpha chain family. (1052 aa)
	PAX6	Paired box 6. (498 aa)
	MERTK	MER proto-oncogene, tyrosine kinase. (998 aa)
	ID1	Inhibitor of DNA binding 1, dominant negative helix-loop-helix protein. (154 aa)
	RLBP1	Retinaldehyde binding protein 1. (384 aa)
	CSPG5	Chondroitin sulfate proteoglycan 5. (615 aa)
	GAS6	Uncharacterized protein. (682 aa)
	SERPINF1	Serpin family F member 1; Belongs to the serpin family. (433 aa)
	TAGLN	Transgelin; Belongs to the calponin family. (239 aa)
	ITGB5	Integrin beta; Belongs to the integrin beta chain family. (800 aa)
	MITF	Microphthalmia-associated transcription factor isoform 1. (520 aa)
	MFAP3L	Microfibril associated protein 3 like. (514 aa)
	CNN3	Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (328 aa)

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BEST1	MERTK	ENSSSCP00000025663	ENSSSCP00000038111	Bestrophin-1; Forms calcium-sensitive chloride channels. Permeable to bicarbonate (By similarity); Belongs to the bestrophin family.	MER proto-oncogene, tyrosine kinase.	0.786
BEST1	MITF	ENSSSCP00000025663	ENSSSCP00000051180	Bestrophin-1; Forms calcium-sensitive chloride channels. Permeable to bicarbonate (By similarity); Belongs to the bestrophin family.	Microphthalmia-associated transcription factor isoform 1.	0.734
BEST1	PAX6	ENSSSCP00000025663	ENSSSCP00000033621	Bestrophin-1; Forms calcium-sensitive chloride channels. Permeable to bicarbonate (By similarity); Belongs to the bestrophin family.	Paired box 6.	0.590
BEST1	RLBP1	ENSSSCP00000025663	ENSSSCP00000041134	Bestrophin-1; Forms calcium-sensitive chloride channels. Permeable to bicarbonate (By similarity); Belongs to the bestrophin family.	Retinaldehyde binding protein 1.	0.759
BEST1	RPE65	ENSSSCP00000025663	ENSSSCP00000004105	Bestrophin-1; Forms calcium-sensitive chloride channels. Permeable to bicarbonate (By similarity); Belongs to the bestrophin family.	Retinoid isomerohydrolase RPE65.	0.903
BEST1	SERPINF1	ENSSSCP00000025663	ENSSSCP00000049229	Bestrophin-1; Forms calcium-sensitive chloride channels. Permeable to bicarbonate (By similarity); Belongs to the bestrophin family.	Serpin family F member 1; Belongs to the serpin family.	0.567
BEST1	TYR	ENSSSCP00000025663	ENSSSCP00000028210	Bestrophin-1; Forms calcium-sensitive chloride channels. Permeable to bicarbonate (By similarity); Belongs to the bestrophin family.	Tyrosinase.	0.625
CNN3	PXDN	ENSSSCP00000060424	ENSSSCP00000022033	Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.	Peroxidasin.	0.446
CSPG5	ID1	ENSSSCP00000043854	ENSSSCP00000040237	Chondroitin sulfate proteoglycan 5.	Inhibitor of DNA binding 1, dominant negative helix-loop-helix protein.	0.466
CSPG5	MFAP3L	ENSSSCP00000043854	ENSSSCP00000051630	Chondroitin sulfate proteoglycan 5.	Microfibril associated protein 3 like.	0.901
CSPG5	NAV3	ENSSSCP00000043854	ENSSSCP00000026430	Chondroitin sulfate proteoglycan 5.	Neuron navigator 3.	0.738
CSPG5	PAK1IP1	ENSSSCP00000043854	ENSSSCP00000030936	Chondroitin sulfate proteoglycan 5.	PAK1 interacting protein 1.	0.916
CSPG5	PTPRG	ENSSSCP00000043854	ENSSSCP00000012239	Chondroitin sulfate proteoglycan 5.	Protein tyrosine phosphatase receptor type G.	0.767
GAS6	MERTK	ENSSSCP00000048949	ENSSSCP00000038111	Uncharacterized protein.	MER proto-oncogene, tyrosine kinase.	0.999
ID1	CSPG5	ENSSSCP00000040237	ENSSSCP00000043854	Inhibitor of DNA binding 1, dominant negative helix-loop-helix protein.	Chondroitin sulfate proteoglycan 5.	0.466
ITGA5	ITGAV	ENSSSCP00000000308	ENSSSCP00000031102	Integrin subunit alpha 5; Belongs to the integrin alpha chain family.	Integrin subunit alpha V; Belongs to the integrin alpha chain family.	0.717
ITGA5	ITGB5	ENSSSCP00000000308	ENSSSCP00000049436	Integrin subunit alpha 5; Belongs to the integrin alpha chain family.	Integrin beta; Belongs to the integrin beta chain family.	0.934
ITGAV	ITGA5	ENSSSCP00000031102	ENSSSCP00000000308	Integrin subunit alpha V; Belongs to the integrin alpha chain family.	Integrin subunit alpha 5; Belongs to the integrin alpha chain family.	0.717
ITGAV	ITGB5	ENSSSCP00000031102	ENSSSCP00000049436	Integrin subunit alpha V; Belongs to the integrin alpha chain family.	Integrin beta; Belongs to the integrin beta chain family.	0.994
ITGB5	ITGA5	ENSSSCP00000049436	ENSSSCP00000000308	Integrin beta; Belongs to the integrin beta chain family.	Integrin subunit alpha 5; Belongs to the integrin alpha chain family.	0.934