STRINGSTRING
NANOG NANOG APOBEC1 APOBEC1 IRX3 IRX3 NPPA NPPA VIRMA VIRMA CTSS CTSS RBM15 RBM15 RBM15B RBM15B MYOD1 MYOD1 MED13 MED13 YTHDF1 YTHDF1 RPGRIP1L RPGRIP1L RARA RARA ASB2 ASB2 ALKBH5 ALKBH5 METTL14 METTL14 FLNA FLNA YTHDF3 YTHDF3 YTHDC2 YTHDC2 NSUN2 NSUN2 YTHDF2 YTHDF2 EGFR EGFR MYH7 MYH7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NANOGHomeobox domain-containing protein. (304 aa)
APOBEC1Apolipoprotein B mRNA editing enzyme catalytic subunit 1. (236 aa)
IRX3Iroquois-class homeodomain protein IRX-3 isoform X2. (502 aa)
NPPAAtrial natriuretic factor; Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3 (By similarity); Belongs to the natriuretic peptide family. (152 aa)
VIRMAVir like m6A methyltransferase associated. (1812 aa)
CTSSCathepsin S; Belongs to the peptidase C1 family. (341 aa)
RBM15RNA binding motif protein 15. (1006 aa)
RBM15BRNA binding motif protein 15B. (854 aa)
MYOD1Myoblast determination protein 1; Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. Together with MYF5 and MYOG, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts. Interacts with and is inhibited by the twist protein. This interaction probably involves the basic domains of both proteins (By similarity). (319 aa)
MED13Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (2173 aa)
YTHDF1YTH N6-methyladenosine RNA binding protein 1. (652 aa)
RPGRIP1LProtein fantom isoform X1. (1270 aa)
RARARetinoic acid receptor alpha isoform X1. (462 aa)
ASB2Ankyrin repeat and SOCS box containing 2. (607 aa)
ALKBH5AlkB homolog 5, RNA demethylase. (394 aa)
METTL14N6-adenosine-methyltransferase non-catalytic subunit; Belongs to the MT-A70-like family. (456 aa)
FLNAFilamin A. (2897 aa)
YTHDF3YTH domain-containing family protein 3 isoform b. (588 aa)
YTHDC2YTH domain containing 2. (1430 aa)
NSUN2NOP2/Sun RNA methyltransferase 2; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (992 aa)
YTHDF2YTH N6-methyladenosine RNA binding protein 2. (600 aa)
EGFRReceptor protein-tyrosine kinase. (1205 aa)
MYH7Myosin-7; Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2052 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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