(15 nodes) (2019) Neural cell adhesion molecule Negr1 deficiency in mouse results in structural brain endophenotypes and behavioral deviations related to psychiatric disorders. network (Sus scrofa)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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Predicted Interactions

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Your Input:
	SYN3	Synapsin III. (580 aa)
	ITK	Tyrosine-protein kinase. (598 aa)
	FGFR2	Fibroblast growth factor receptor. (820 aa)
	SYN1	Synapsin-1 isoform Ia. (712 aa)
	LSAMP	Limbic system associated membrane protein. (345 aa)
	PXDN	Peroxidasin. (1529 aa)
	PVALB	Parvalbumin alpha; Belongs to the parvalbumin family. (141 aa)
	SRGAP3	SLIT-ROBO Rho GTPase activating protein 3. (1074 aa)
	NEGR1	Neuronal growth regulator 1. (354 aa)
	SYN2	Synapsin II. (581 aa)
	NTM	Neurotrimin. (344 aa)
	OPCML	Opioid-binding protein/cell adhesion molecule isoform a preproprotein. (345 aa)
	NPC2	NPC intracellular cholesterol transporter 2; Intracellular cholesterol transporter which acts in concert with NPC1 and plays an important role in the egress of cholesterol from the lysosomal compartment. Unesterified cholesterol that has been released from LDLs in the lumen of the late endosomes/lysosomes is transferred by NPC2 to the cholesterol-binding pocket in the N-terminal domain of NPC1. May bind and mobilize cholesterol that is associated with membranes (By similarity). NPC2 binds cholesterol with a 1:1 stoichiometry. Can bind a variety of sterols, including lathosterol, desmos [...] (154 aa)
	LOC100512905	Uncharacterized protein. (393 aa)
	LOC110261043	Uncharacterized protein. (387 aa)

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC100512905	LSAMP	ENSSSCP00000039620	ENSSSCP00000022632	Uncharacterized protein.	Limbic system associated membrane protein.	0.469
LOC100512905	NEGR1	ENSSSCP00000039620	ENSSSCP00000053381	Uncharacterized protein.	Neuronal growth regulator 1.	0.543
LOC100512905	SRGAP3	ENSSSCP00000039620	ENSSSCP00000052411	Uncharacterized protein.	SLIT-ROBO Rho GTPase activating protein 3.	0.422
LOC110261043	LSAMP	ENSSSCP00000038861	ENSSSCP00000022632	Uncharacterized protein.	Limbic system associated membrane protein.	0.473
LOC110261043	NEGR1	ENSSSCP00000038861	ENSSSCP00000053381	Uncharacterized protein.	Neuronal growth regulator 1.	0.546
LOC110261043	SRGAP3	ENSSSCP00000038861	ENSSSCP00000052411	Uncharacterized protein.	SLIT-ROBO Rho GTPase activating protein 3.	0.457
LSAMP	LOC100512905	ENSSSCP00000022632	ENSSSCP00000039620	Limbic system associated membrane protein.	Uncharacterized protein.	0.469
LSAMP	LOC110261043	ENSSSCP00000022632	ENSSSCP00000038861	Limbic system associated membrane protein.	Uncharacterized protein.	0.473
LSAMP	NEGR1	ENSSSCP00000022632	ENSSSCP00000053381	Limbic system associated membrane protein.	Neuronal growth regulator 1.	0.530
LSAMP	NTM	ENSSSCP00000022632	ENSSSCP00000062098	Limbic system associated membrane protein.	Neurotrimin.	0.535
NEGR1	LOC100512905	ENSSSCP00000053381	ENSSSCP00000039620	Neuronal growth regulator 1.	Uncharacterized protein.	0.543
NEGR1	LOC110261043	ENSSSCP00000053381	ENSSSCP00000038861	Neuronal growth regulator 1.	Uncharacterized protein.	0.546
NEGR1	LSAMP	ENSSSCP00000053381	ENSSSCP00000022632	Neuronal growth regulator 1.	Limbic system associated membrane protein.	0.530
NEGR1	NPC2	ENSSSCP00000053381	ENSSSCP00000073764	Neuronal growth regulator 1.	NPC intracellular cholesterol transporter 2; Intracellular cholesterol transporter which acts in concert with NPC1 and plays an important role in the egress of cholesterol from the lysosomal compartment. Unesterified cholesterol that has been released from LDLs in the lumen of the late endosomes/lysosomes is transferred by NPC2 to the cholesterol-binding pocket in the N-terminal domain of NPC1. May bind and mobilize cholesterol that is associated with membranes (By similarity). NPC2 binds cholesterol with a 1:1 stoichiometry. Can bind a variety of sterols, including lathosterol, desmos [...]	0.407
NEGR1	SRGAP3	ENSSSCP00000053381	ENSSSCP00000052411	Neuronal growth regulator 1.	SLIT-ROBO Rho GTPase activating protein 3.	0.669
NEGR1	SYN2	ENSSSCP00000053381	ENSSSCP00000061192	Neuronal growth regulator 1.	Synapsin II.	0.400
NEGR1	SYN3	ENSSSCP00000053381	ENSSSCP00000034146	Neuronal growth regulator 1.	Synapsin III.	0.400
NPC2	NEGR1	ENSSSCP00000073764	ENSSSCP00000053381	NPC intracellular cholesterol transporter 2; Intracellular cholesterol transporter which acts in concert with NPC1 and plays an important role in the egress of cholesterol from the lysosomal compartment. Unesterified cholesterol that has been released from LDLs in the lumen of the late endosomes/lysosomes is transferred by NPC2 to the cholesterol-binding pocket in the N-terminal domain of NPC1. May bind and mobilize cholesterol that is associated with membranes (By similarity). NPC2 binds cholesterol with a 1:1 stoichiometry. Can bind a variety of sterols, including lathosterol, desmos [...]	Neuronal growth regulator 1.	0.407
NTM	LSAMP	ENSSSCP00000062098	ENSSSCP00000022632	Neurotrimin.	Limbic system associated membrane protein.	0.535
NTM	SRGAP3	ENSSSCP00000062098	ENSSSCP00000052411	Neurotrimin.	SLIT-ROBO Rho GTPase activating protein 3.	0.420