STRINGSTRING
YTHDF2 YTHDF2 METTL6 METTL6 ADAR ADAR TRMT5 TRMT5 PUS1 PUS1 TRMT6 TRMT6 NAT10 NAT10 QTRT1 QTRT1 ELP2 ELP2 IGF2BP1 IGF2BP1 ALKBH8 ALKBH8 TRMT61B TRMT61B ALKBH1 ALKBH1 IGF2BP2 IGF2BP2 YTHDF1 YTHDF1 ADAT3 ADAT3 TRMT61A TRMT61A ALKBH5 ALKBH5 NSUN7 NSUN7 IGF2BP3 IGF2BP3 METTL8 METTL8 METTL14 METTL14 CTU2 CTU2 CTU1 CTU1 ADAT2 ADAT2 ALYREF ALYREF YBX1 YBX1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
YTHDF2YTH N6-methyladenosine RNA binding protein 2. (600 aa)
METTL6Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family. (284 aa)
ADARAdenosine deaminase RNA specific. (1169 aa)
TRMT5tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family. (504 aa)
PUS1Pseudouridine synthase 1. (433 aa)
TRMT6tRNA methyltransferase 6. (693 aa)
NAT10RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (1026 aa)
QTRT1Queuine tRNA-ribosyltransferase catalytic subunit 1; Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, formi [...] (403 aa)
ELP2Elongator acetyltransferase complex subunit 2. (826 aa)
IGF2BP1Insulin-like growth factor 2 mRNA-binding protein 1 isoform X1. (577 aa)
ALKBH8AlkB homolog 8, tRNA methyltransferase. (614 aa)
TRMT61BtRNA methyltransferase 61B. (492 aa)
ALKBH1AlkB homolog 1, histone H2A dioxygenase. (425 aa)
IGF2BP2Insulin like growth factor 2 mRNA binding protein 2. (592 aa)
YTHDF1YTH N6-methyladenosine RNA binding protein 1. (652 aa)
ADAT3Putative inactive tRNA-specific adenosine deaminase-like protein 3 isoform 1. (351 aa)
TRMT61AtRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A; Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. (285 aa)
ALKBH5AlkB homolog 5, RNA demethylase. (394 aa)
NSUN7NOP2/Sun RNA methyltransferase family member 7; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (724 aa)
IGF2BP3Insulin-like growth factor 2 mRNA-binding protein 3. (586 aa)
METTL8Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family. (426 aa)
METTL14N6-adenosine-methyltransferase non-catalytic subunit; Belongs to the MT-A70-like family. (456 aa)
CTU2Cytoplasmic tRNA 2-thiolation protein 2; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with CTU1/ATPBD3 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Belongs to the CTU2/NCS2 family. (591 aa)
CTU1Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position; Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily. (343 aa)
ADAT2Adenosine deaminase tRNA specific 2. (230 aa)
ALYREFAly/REF export factor. (348 aa)
YBX1Y-box binding protein 1. (419 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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