6 items (Sus scrofa) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
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Predicted Interactions

gene neighborhood

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Others

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co-expression

protein homology

Your Input:
	MUC4	Uncharacterized protein. (1173 aa)
	MUC1	SEA domain-containing protein. (638 aa)
	EPCAM	Epithelial cell adhesion molecule; May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E (By similarity). Belongs to the EPCAM family. (340 aa)
	CFTR	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...] (1482 aa)
	MUC5AC	Uncharacterized protein. (3330 aa)
	KRT8	Keratin, type II cytoskeletal 8 isoform 2; Belongs to the intermediate filament family. (461 aa)

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CFTR	KRT8	ENSSSCP00000036792	ENSSSCP00000046493	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]	Keratin, type II cytoskeletal 8 isoform 2; Belongs to the intermediate filament family.	0.404
CFTR	MUC5AC	ENSSSCP00000036792	ENSSSCP00000045466	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]	Uncharacterized protein.	0.679
EPCAM	KRT8	ENSSSCP00000008996	ENSSSCP00000046493	Epithelial cell adhesion molecule; May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E (By similarity). Belongs to the EPCAM family.	Keratin, type II cytoskeletal 8 isoform 2; Belongs to the intermediate filament family.	0.677
EPCAM	MUC1	ENSSSCP00000008996	ENSSSCP00000006953	Epithelial cell adhesion molecule; May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E (By similarity). Belongs to the EPCAM family.	SEA domain-containing protein.	0.654
KRT8	CFTR	ENSSSCP00000046493	ENSSSCP00000036792	Keratin, type II cytoskeletal 8 isoform 2; Belongs to the intermediate filament family.	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]	0.404
KRT8	EPCAM	ENSSSCP00000046493	ENSSSCP00000008996	Keratin, type II cytoskeletal 8 isoform 2; Belongs to the intermediate filament family.	Epithelial cell adhesion molecule; May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E (By similarity). Belongs to the EPCAM family.	0.677
KRT8	MUC1	ENSSSCP00000046493	ENSSSCP00000006953	Keratin, type II cytoskeletal 8 isoform 2; Belongs to the intermediate filament family.	SEA domain-containing protein.	0.518
MUC1	EPCAM	ENSSSCP00000006953	ENSSSCP00000008996	SEA domain-containing protein.	Epithelial cell adhesion molecule; May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E (By similarity). Belongs to the EPCAM family.	0.654
MUC1	KRT8	ENSSSCP00000006953	ENSSSCP00000046493	SEA domain-containing protein.	Keratin, type II cytoskeletal 8 isoform 2; Belongs to the intermediate filament family.	0.518
MUC1	MUC4	ENSSSCP00000006953	ENSSSCP00000051590	SEA domain-containing protein.	Uncharacterized protein.	0.963
MUC1	MUC5AC	ENSSSCP00000006953	ENSSSCP00000045466	SEA domain-containing protein.	Uncharacterized protein.	0.917
MUC4	MUC1	ENSSSCP00000051590	ENSSSCP00000006953	Uncharacterized protein.	SEA domain-containing protein.	0.963
MUC4	MUC5AC	ENSSSCP00000051590	ENSSSCP00000045466	Uncharacterized protein.	Uncharacterized protein.	0.944
MUC5AC	CFTR	ENSSSCP00000045466	ENSSSCP00000036792	Uncharacterized protein.	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]	0.679
MUC5AC	MUC1	ENSSSCP00000045466	ENSSSCP00000006953	Uncharacterized protein.	SEA domain-containing protein.	0.917
MUC5AC	MUC4	ENSSSCP00000045466	ENSSSCP00000051590	Uncharacterized protein.	Uncharacterized protein.	0.944