STRINGSTRING
USP10 USP10 MTOR MTOR FUBP1 FUBP1 SYNCRIP SYNCRIP IFNB1 IFNB1 VIRMA VIRMA RBM15 RBM15 MAVS MAVS PABPC1L PABPC1L ANXA4 ANXA4 ZC3H13 ZC3H13 GBF1 GBF1 FXR2 FXR2 EIF5B EIF5B HNRNPK HNRNPK PABPC1 PABPC1 EIF4E EIF4E FMR1 FMR1 YTHDF1 YTHDF1 HNRNPA1 HNRNPA1 GEMIN5 GEMIN5 ARF1 ARF1 EIF2S1 EIF2S1 SAR1A SAR1A WTAP WTAP ERI3 ERI3 METTL14 METTL14 YTHDC2 YTHDC2 EIF3B EIF3B G3BP2 G3BP2 CAPRIN1 CAPRIN1 PABPC4 PABPC4 ARF6 ARF6 PCBP2 PCBP2 COPA COPA YTHDF2 YTHDF2 ARF4 ARF4 ARF5 ARF5 SEC13 SEC13 UBAP2L UBAP2L
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
USP10Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (805 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2548 aa)
FUBP1Far upstream element-binding protein 1 isoform X2. (664 aa)
SYNCRIPSynaptotagmin binding cytoplasmic RNA interacting protein. (623 aa)
IFNB1Interferon-beta-1. (186 aa)
VIRMAVir like m6A methyltransferase associated. (1812 aa)
RBM15RNA binding motif protein 15. (1006 aa)
MAVSMitochondrial antiviral signaling protein. (532 aa)
PABPC1LPolyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (610 aa)
ANXA4Annexin A4; Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis; Belongs to the annexin family. (337 aa)
ZC3H13Zinc finger CCCH-type containing 13. (1640 aa)
GBF1Golgi brefeldin A resistant guanine nucleotide exchange factor 1. (1859 aa)
FXR2FMR1 autosomal homolog 2. (667 aa)
EIF5BEukaryotic translation initiation factor 5B. (1225 aa)
HNRNPKUncharacterized protein. (464 aa)
PABPC1Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (636 aa)
EIF4EEukaryotic translation initiation factor 4E; Belongs to the eukaryotic initiation factor 4E family. (237 aa)
FMR1Fragile X mental retardation protein 1. (632 aa)
YTHDF1YTH N6-methyladenosine RNA binding protein 1. (652 aa)
HNRNPA1Heterogeneous nuclear ribonucleoprotein A1. (373 aa)
GEMIN5Gem nuclear organelle associated protein 5. (1511 aa)
ARF1ADP ribosylation factor 1; Belongs to the small GTPase superfamily. Arf family. (211 aa)
EIF2S1Eukaryotic translation initiation factor 2 subunit 1; Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S pre- initiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF- 2 must exchange with GTP by way of a reaction catalyzed [...] (315 aa)
SAR1AGTP-binding protein SAR1a; Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES) (By similarity). (198 aa)
WTAPUncharacterized protein. (649 aa)
ERI3ERI1 exoribonuclease family member 3. (317 aa)
METTL14N6-adenosine-methyltransferase non-catalytic subunit; Belongs to the MT-A70-like family. (456 aa)
YTHDC2YTH domain containing 2. (1430 aa)
EIF3BEukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome; Belongs to the eIF-3 subunit B family. (784 aa)
G3BP2Ras GTPase-activating protein-binding protein 2 isoform X1. (481 aa)
CAPRIN1Cell cycle associated protein 1. (709 aa)
PABPC4Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (660 aa)
ARF6ADP-ribosylation factor 6; GTP-binding protein involved in protein trafficking that regulates endocytic recycling and cytoskeleton remodeling (By similarity). Required for normal completion of mitotic cytokinesis (By similarity). Plays a role in the reorganization of the actin cytoskeleton and the formation of stress fibers (By similarity). Involved in the regulation of dendritic spine development, contributing to the regulation of dendritic branching and filopodia extension (By similarity). Plays an important role in membrane trafficking, during junctional remodeling and epithelial po [...] (175 aa)
PCBP2Poly(rC) binding protein 2. (467 aa)
COPACoatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. (1241 aa)
YTHDF2YTH N6-methyladenosine RNA binding protein 2. (600 aa)
ARF4ADP ribosylation factor 4; Belongs to the small GTPase superfamily. Arf family. (183 aa)
ARF5Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (207 aa)
SEC13SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family. (341 aa)
UBAP2LUbiquitin associated protein 2 like. (1137 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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