node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
A0A286ZTM7_PIG | ACTB | ENSSSCP00000034926 | ENSSSCP00000035521 | Histone H3; Belongs to the histone H3 family. | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | 0.772 |
A0A286ZTM7_PIG | HIST1H3E | ENSSSCP00000034926 | ENSSSCP00000053406 | Histone H3; Belongs to the histone H3 family. | Histone H3; Belongs to the histone H3 family. | 0.953 |
A0A286ZTM7_PIG | LOC100521680 | ENSSSCP00000034926 | ENSSSCP00000018225 | Histone H3; Belongs to the histone H3 family. | Histone H3.3; Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in [...] | 0.900 |
ACTB | A0A286ZTM7_PIG | ENSSSCP00000035521 | ENSSSCP00000034926 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | Histone H3; Belongs to the histone H3 family. | 0.772 |
ACTB | CYCS | ENSSSCP00000035521 | ENSSSCP00000017704 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. | 0.710 |
ACTB | EIF4E | ENSSSCP00000035521 | ENSSSCP00000027266 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | Eukaryotic translation initiation factor 4E; Belongs to the eukaryotic initiation factor 4E family. | 0.634 |
ACTB | HIST1H3E | ENSSSCP00000035521 | ENSSSCP00000053406 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | Histone H3; Belongs to the histone H3 family. | 0.773 |
ACTB | HNRNPA1 | ENSSSCP00000035521 | ENSSSCP00000033484 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | Heterogeneous nuclear ribonucleoprotein A1. | 0.476 |
ACTB | LOC100519295 | ENSSSCP00000035521 | ENSSSCP00000025813 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. | 0.549 |
ACTB | LOC100521680 | ENSSSCP00000035521 | ENSSSCP00000018225 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | Histone H3.3; Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in [...] | 0.772 |
ACTB | RPS18 | ENSSSCP00000035521 | ENSSSCP00000001631 | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. | 40S ribosomal protein S18; Located at the top of the head of the 40S subunit, it contacts several helices of the 18S rRNA; Belongs to the universal ribosomal protein uS13 family. | 0.510 |
ASCC3 | CELF1 | ENSSSCP00000042651 | ENSSSCP00000051386 | Activating signal cointegrator 1 complex subunit 3. | CUGBP Elav-like family member 1. | 0.515 |
ASCC3 | DCP1A | ENSSSCP00000042651 | ENSSSCP00000023625 | Activating signal cointegrator 1 complex subunit 3. | mRNA-decapping enzyme 1A; Necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. Contributes to the transactivation of target genes after stimulation by TGFB1; Belongs to the DCP1 family. | 0.428 |
ASCC3 | GEMIN5 | ENSSSCP00000042651 | ENSSSCP00000036144 | Activating signal cointegrator 1 complex subunit 3. | Gem nuclear organelle associated protein 5. | 0.525 |
ASCC3 | GIGYF2 | ENSSSCP00000042651 | ENSSSCP00000034185 | Activating signal cointegrator 1 complex subunit 3. | GRB10 interacting GYF protein 2. | 0.788 |
ASCC3 | NUDT3 | ENSSSCP00000042651 | ENSSSCP00000063223 | Activating signal cointegrator 1 complex subunit 3. | Nudix hydrolase domain-containing protein. | 0.545 |
ASCC3 | SERBP1 | ENSSSCP00000042651 | ENSSSCP00000004109 | Activating signal cointegrator 1 complex subunit 3. | Plasminogen activator inhibitor 1 RNA-binding protein isoform 1. | 0.485 |
ASCC3 | TIA1 | ENSSSCP00000042651 | ENSSSCP00000026866 | Activating signal cointegrator 1 complex subunit 3. | TIA1 cytotoxic granule associated RNA binding protein. | 0.423 |
ASCC3 | XRN1 | ENSSSCP00000042651 | ENSSSCP00000067024 | Activating signal cointegrator 1 complex subunit 3. | 5'-3' exoribonuclease 1. | 0.418 |
ASCC3 | YTHDC2 | ENSSSCP00000042651 | ENSSSCP00000048904 | Activating signal cointegrator 1 complex subunit 3. | YTH domain containing 2. | 0.606 |