STRINGSTRING
TRIM25 TRIM25 XRN1 XRN1 SND1 SND1 YTHDF2 YTHDF2 MTDH MTDH NUDT3 NUDT3 NSUN2 NSUN2 HIST1H3E HIST1H3E CELF1 CELF1 YTHDC2 YTHDC2 METTL8 METTL8 ASCC3 ASCC3 ZC3HAV1 ZC3HAV1 GEMIN5 GEMIN5 ACTB ACTB A0A286ZTM7_PIG A0A286ZTM7_PIG GIGYF2 GIGYF2 HNRNPA1 HNRNPA1 YTHDF1 YTHDF1 EIF4E EIF4E TIA1 TIA1 RPS18 RPS18 SERBP1 SERBP1 LOC100519295 LOC100519295 CYCS CYCS LOC100521680 LOC100521680 ZNF598 ZNF598 DCP1A DCP1A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TRIM25Tripartite motif containing 25. (633 aa)
XRN15'-3' exoribonuclease 1. (1703 aa)
SND1Staphylococcal nuclease domain-containing protein; Endonuclease that mediates miRNA decay of both protein-free and AGO2-loaded miRNAs. (910 aa)
YTHDF2YTH N6-methyladenosine RNA binding protein 2. (600 aa)
MTDHMetadherin. (613 aa)
NUDT3Nudix hydrolase domain-containing protein. (291 aa)
NSUN2NOP2/Sun RNA methyltransferase 2; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (992 aa)
HIST1H3EHistone H3; Belongs to the histone H3 family. (136 aa)
CELF1CUGBP Elav-like family member 1. (551 aa)
YTHDC2YTH domain containing 2. (1430 aa)
METTL8Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family. (426 aa)
ASCC3Activating signal cointegrator 1 complex subunit 3. (2203 aa)
ZC3HAV1Zinc finger CCCH-type antiviral protein 1 isoform 1. (894 aa)
GEMIN5Gem nuclear organelle associated protein 5. (1511 aa)
ACTBActin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (375 aa)
A0A286ZTM7_PIGHistone H3; Belongs to the histone H3 family. (136 aa)
GIGYF2GRB10 interacting GYF protein 2. (1310 aa)
HNRNPA1Heterogeneous nuclear ribonucleoprotein A1. (373 aa)
YTHDF1YTH N6-methyladenosine RNA binding protein 1. (652 aa)
EIF4EEukaryotic translation initiation factor 4E; Belongs to the eukaryotic initiation factor 4E family. (237 aa)
TIA1TIA1 cytotoxic granule associated RNA binding protein. (386 aa)
RPS1840S ribosomal protein S18; Located at the top of the head of the 40S subunit, it contacts several helices of the 18S rRNA; Belongs to the universal ribosomal protein uS13 family. (152 aa)
SERBP1Plasminogen activator inhibitor 1 RNA-binding protein isoform 1. (407 aa)
LOC100519295Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
CYCSCytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
LOC100521680Histone H3.3; Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in [...] (136 aa)
ZNF598Zinc finger protein 598. (900 aa)
DCP1AmRNA-decapping enzyme 1A; Necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. Contributes to the transactivation of target genes after stimulation by TGFB1; Belongs to the DCP1 family. (580 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.