27 items (Sus scrofa) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	SMAD6	Mothers against decapentaplegic homolog. (496 aa)
	ACTB	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (375 aa)
	YTHDF1	YTH N6-methyladenosine RNA binding protein 1. (652 aa)
	ENG	Endoglin; Vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis. Required for normal structure and integrity of adult vasculature. Regulates the migration of vascular endothelial cells (By similarity). Required for normal extraembryonic angiogenesis and for embryonic heart development (By similarity). May regulate endothelial cell shape changes in response to blood flow, which drive vascular remodeling and establishment of normal vascular morphology during angiogenesis (By similarity). May play a role in the binding of endothelial cells to int [...] (619 aa)
	IGF2BP2	Insulin like growth factor 2 mRNA binding protein 2. (592 aa)
	METTL3	N6-adenosine-methyltransferase catalytic subunit; Belongs to the MT-A70-like family. (580 aa)
	PXDN	Peroxidasin. (1529 aa)
	COL1A2	Fibrillar collagen NC1 domain-containing protein. (1135 aa)
	MAGED1	Melanoma-associated antigen D1; Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal cells. Inhibits cell cycle progression, and facilitates NGFR-mediated apoptosis. May act as a regulator of the function of DLX family members. May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl- conjugating enzyme (E2) at the E3:substrate complex. Plays a role in the circadian rhythm regulation. May act as RORA co-regulator, modulating the expression [...] (835 aa)
	SMAD9	Mothers against decapentaplegic homolog. (467 aa)
	RBM15	RNA binding motif protein 15. (1006 aa)
	VIRMA	Vir like m6A methyltransferase associated. (1812 aa)
	LDHA	L-lactate dehydrogenase A chain. (443 aa)
	MTOR	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2548 aa)
	LDHB	L-lactate dehydrogenase B chain; Belongs to the LDH/MDH superfamily. LDH family. (377 aa)
	ACVRL1	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (595 aa)
	LDHB-2	L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (334 aa)
	YTHDF2	YTH N6-methyladenosine RNA binding protein 2. (600 aa)
	COL1A1	Collagen type I alpha 1 chain. (1477 aa)
	PKM	Multifunctional fusion protein; Belongs to the pyruvate kinase family. (1202 aa)
	YTHDC2	YTH domain containing 2. (1430 aa)
	YTHDF3	YTH domain-containing family protein 3 isoform b. (588 aa)
	FTO	FTO_NTD domain-containing protein. (509 aa)
	METTL14	N6-adenosine-methyltransferase non-catalytic subunit; Belongs to the MT-A70-like family. (456 aa)
	IGF2BP3	Insulin-like growth factor 2 mRNA-binding protein 3. (586 aa)
	WTAP	Uncharacterized protein. (649 aa)
	ALKBH5	AlkB homolog 5, RNA demethylase. (394 aa)

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTB	COL1A1	ENSSSCP00000035521	ENSSSCP00000066291	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Collagen type I alpha 1 chain.	0.713
ACTB	COL1A2	ENSSSCP00000035521	ENSSSCP00000016253	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Fibrillar collagen NC1 domain-containing protein.	0.519
ACTB	ENG	ENSSSCP00000035521	ENSSSCP00000030121	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Endoglin; Vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis. Required for normal structure and integrity of adult vasculature. Regulates the migration of vascular endothelial cells (By similarity). Required for normal extraembryonic angiogenesis and for embryonic heart development (By similarity). May regulate endothelial cell shape changes in response to blood flow, which drive vascular remodeling and establishment of normal vascular morphology during angiogenesis (By similarity). May play a role in the binding of endothelial cells to int [...]	0.514
ACTB	LDHA	ENSSSCP00000035521	ENSSSCP00000036508	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	L-lactate dehydrogenase A chain.	0.513
ACTB	MTOR	ENSSSCP00000035521	ENSSSCP00000003699	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.	0.516
ACTB	PKM	ENSSSCP00000035521	ENSSSCP00000051975	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Multifunctional fusion protein; Belongs to the pyruvate kinase family.	0.519
ACTB	PXDN	ENSSSCP00000035521	ENSSSCP00000022033	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Peroxidasin.	0.951
ACVRL1	ENG	ENSSSCP00000000247	ENSSSCP00000030121	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Endoglin; Vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis. Required for normal structure and integrity of adult vasculature. Regulates the migration of vascular endothelial cells (By similarity). Required for normal extraembryonic angiogenesis and for embryonic heart development (By similarity). May regulate endothelial cell shape changes in response to blood flow, which drive vascular remodeling and establishment of normal vascular morphology during angiogenesis (By similarity). May play a role in the binding of endothelial cells to int [...]	0.807
ACVRL1	SMAD6	ENSSSCP00000000247	ENSSSCP00000005325	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Mothers against decapentaplegic homolog.	0.547
ACVRL1	SMAD9	ENSSSCP00000000247	ENSSSCP00000009987	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Mothers against decapentaplegic homolog.	0.733
ALKBH5	FTO	ENSSSCP00000038766	ENSSSCP00000047110	AlkB homolog 5, RNA demethylase.	FTO_NTD domain-containing protein.	0.979
ALKBH5	IGF2BP2	ENSSSCP00000038766	ENSSSCP00000028307	AlkB homolog 5, RNA demethylase.	Insulin like growth factor 2 mRNA binding protein 2.	0.675
ALKBH5	IGF2BP3	ENSSSCP00000038766	ENSSSCP00000044238	AlkB homolog 5, RNA demethylase.	Insulin-like growth factor 2 mRNA-binding protein 3.	0.685
ALKBH5	METTL14	ENSSSCP00000038766	ENSSSCP00000046701	AlkB homolog 5, RNA demethylase.	N6-adenosine-methyltransferase non-catalytic subunit; Belongs to the MT-A70-like family.	0.953
ALKBH5	METTL3	ENSSSCP00000038766	ENSSSCP00000023249	AlkB homolog 5, RNA demethylase.	N6-adenosine-methyltransferase catalytic subunit; Belongs to the MT-A70-like family.	0.873
ALKBH5	RBM15	ENSSSCP00000038766	ENSSSCP00000007262	AlkB homolog 5, RNA demethylase.	RNA binding motif protein 15.	0.853
ALKBH5	VIRMA	ENSSSCP00000038766	ENSSSCP00000006511	AlkB homolog 5, RNA demethylase.	Vir like m6A methyltransferase associated.	0.828
ALKBH5	WTAP	ENSSSCP00000038766	ENSSSCP00000039764	AlkB homolog 5, RNA demethylase.	Uncharacterized protein.	0.975
ALKBH5	YTHDC2	ENSSSCP00000038766	ENSSSCP00000048904	AlkB homolog 5, RNA demethylase.	YTH domain containing 2.	0.858
ALKBH5	YTHDF1	ENSSSCP00000038766	ENSSSCP00000031181	AlkB homolog 5, RNA demethylase.	YTH N6-methyladenosine RNA binding protein 1.	0.917