STRINGSTRING
GCK GCK YTHDC2 YTHDC2 YTHDF3 YTHDF3 METTL14 METTL14 IGF2BP3 IGF2BP3 EDN1 EDN1 WTAP WTAP ALKBH5 ALKBH5 YTHDF1 YTHDF1 IGF2BP2 IGF2BP2 ALKBH1 ALKBH1 SCNN1B SCNN1B N6AMT1 N6AMT1 ADRB3 ADRB3 PRCP PRCP DNMT1 DNMT1 RBM15 RBM15 SULF1 SULF1 VIRMA VIRMA TDG TDG MFN2 MFN2 HIF1A HIF1A YTHDC1 YTHDC1 TLR2 TLR2 YTHDF2 YTHDF2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GCKGlucokinase. (659 aa)
YTHDC2YTH domain containing 2. (1430 aa)
YTHDF3YTH domain-containing family protein 3 isoform b. (588 aa)
METTL14N6-adenosine-methyltransferase non-catalytic subunit; Belongs to the MT-A70-like family. (456 aa)
IGF2BP3Insulin-like growth factor 2 mRNA-binding protein 3. (586 aa)
EDN1Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides. Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family. (203 aa)
WTAPUncharacterized protein. (649 aa)
ALKBH5AlkB homolog 5, RNA demethylase. (394 aa)
YTHDF1YTH N6-methyladenosine RNA binding protein 1. (652 aa)
IGF2BP2Insulin like growth factor 2 mRNA binding protein 2. (592 aa)
ALKBH1AlkB homolog 1, histone H2A dioxygenase. (425 aa)
SCNN1BAmiloride-sensitive sodium channel subunit beta isoform X1; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (644 aa)
N6AMT1N-6 adenine-specific DNA methyltransferase 1. (220 aa)
ADRB3Beta-3 adrenergic receptor; Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. Beta- 3 is involved in the regulation of lipolysis and thermogenesis; Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB3 sub-subfamily. (407 aa)
PRCPProlylcarboxypeptidase. (511 aa)
DNMT1DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1706 aa)
RBM15RNA binding motif protein 15. (1006 aa)
SULF1Sulfatase 1. (1108 aa)
VIRMAVir like m6A methyltransferase associated. (1812 aa)
TDGG/T mismatch-specific thymine DNA glycosylase. (406 aa)
MFN2Mitofusin-2 isoform X1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (757 aa)
HIF1AHypoxia-inducible factor 1-alpha isoform 1. (824 aa)
YTHDC1YTH domain containing 1. (743 aa)
TLR2Toll-like receptor 2; Belongs to the Toll-like receptor family. (785 aa)
YTHDF2YTH N6-methyladenosine RNA binding protein 2. (600 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
Server load: low (12%) [HD]