16 items (Sus scrofa) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	HNRNPC	Heterogeneous nuclear ribonucleoproteins C1/C2 isoform X1. (307 aa)
	PPARG	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (528 aa)
	EIF3H	Eukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (327 aa)
	METTL4	Methyltransferase like 4; Belongs to the MT-A70-like family. (478 aa)
	PPARA	Uncharacterized protein. (469 aa)
	YTHDF2	YTH N6-methyladenosine RNA binding protein 2. (600 aa)
	MYH1	Myosin-2; Muscle contraction. Required for cytoskeleton organization (By similarity). (1956 aa)
	YTHDC2	YTH domain containing 2. (1430 aa)
	YTHDF3	YTH domain-containing family protein 3 isoform b. (588 aa)
	FTO	FTO_NTD domain-containing protein. (509 aa)
	METTL14	N6-adenosine-methyltransferase non-catalytic subunit; Belongs to the MT-A70-like family. (456 aa)
	NCOA2	Nuclear receptor coactivator. (1463 aa)
	WTAP	Uncharacterized protein. (649 aa)
	ALKBH5	AlkB homolog 5, RNA demethylase. (394 aa)
	TNNT1	Troponin T, slow skeletal muscle; Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. (298 aa)
	MYOM2	Uncharacterized protein. (888 aa)

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALKBH5	FTO	ENSSSCP00000038766	ENSSSCP00000047110	AlkB homolog 5, RNA demethylase.	FTO_NTD domain-containing protein.	0.979
ALKBH5	HNRNPC	ENSSSCP00000038766	ENSSSCP00000024485	AlkB homolog 5, RNA demethylase.	Heterogeneous nuclear ribonucleoproteins C1/C2 isoform X1.	0.758
ALKBH5	METTL14	ENSSSCP00000038766	ENSSSCP00000046701	AlkB homolog 5, RNA demethylase.	N6-adenosine-methyltransferase non-catalytic subunit; Belongs to the MT-A70-like family.	0.953
ALKBH5	METTL4	ENSSSCP00000038766	ENSSSCP00000068190	AlkB homolog 5, RNA demethylase.	Methyltransferase like 4; Belongs to the MT-A70-like family.	0.678
ALKBH5	WTAP	ENSSSCP00000038766	ENSSSCP00000039764	AlkB homolog 5, RNA demethylase.	Uncharacterized protein.	0.975
ALKBH5	YTHDC2	ENSSSCP00000038766	ENSSSCP00000048904	AlkB homolog 5, RNA demethylase.	YTH domain containing 2.	0.858
ALKBH5	YTHDF2	ENSSSCP00000038766	ENSSSCP00000065604	AlkB homolog 5, RNA demethylase.	YTH N6-methyladenosine RNA binding protein 2.	0.913
ALKBH5	YTHDF3	ENSSSCP00000038766	ENSSSCP00000048507	AlkB homolog 5, RNA demethylase.	YTH domain-containing family protein 3 isoform b.	0.890
EIF3H	HNRNPC	ENSSSCP00000006426	ENSSSCP00000024485	Eukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...]	Heterogeneous nuclear ribonucleoproteins C1/C2 isoform X1.	0.493
EIF3H	METTL14	ENSSSCP00000006426	ENSSSCP00000046701	Eukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...]	N6-adenosine-methyltransferase non-catalytic subunit; Belongs to the MT-A70-like family.	0.425
EIF3H	WTAP	ENSSSCP00000006426	ENSSSCP00000039764	Eukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...]	Uncharacterized protein.	0.431
FTO	ALKBH5	ENSSSCP00000047110	ENSSSCP00000038766	FTO_NTD domain-containing protein.	AlkB homolog 5, RNA demethylase.	0.979
FTO	HNRNPC	ENSSSCP00000047110	ENSSSCP00000024485	FTO_NTD domain-containing protein.	Heterogeneous nuclear ribonucleoproteins C1/C2 isoform X1.	0.709
FTO	METTL14	ENSSSCP00000047110	ENSSSCP00000046701	FTO_NTD domain-containing protein.	N6-adenosine-methyltransferase non-catalytic subunit; Belongs to the MT-A70-like family.	0.905
FTO	METTL4	ENSSSCP00000047110	ENSSSCP00000068190	FTO_NTD domain-containing protein.	Methyltransferase like 4; Belongs to the MT-A70-like family.	0.594
FTO	PPARG	ENSSSCP00000047110	ENSSSCP00000012339	FTO_NTD domain-containing protein.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.402
FTO	WTAP	ENSSSCP00000047110	ENSSSCP00000039764	FTO_NTD domain-containing protein.	Uncharacterized protein.	0.912
FTO	YTHDC2	ENSSSCP00000047110	ENSSSCP00000048904	FTO_NTD domain-containing protein.	YTH domain containing 2.	0.788
FTO	YTHDF2	ENSSSCP00000047110	ENSSSCP00000065604	FTO_NTD domain-containing protein.	YTH N6-methyladenosine RNA binding protein 2.	0.873
FTO	YTHDF3	ENSSSCP00000047110	ENSSSCP00000048507	FTO_NTD domain-containing protein.	YTH domain-containing family protein 3 isoform b.	0.863