STRINGSTRING
POLR2F POLR2F DDX24 DDX24 RPS11 RPS11 DCAF13 DCAF13 WDR3 WDR3 NOP56 NOP56 COX5B COX5B DHX15 DHX15 UGT2B31 UGT2B31 FGB FGB GNRH1 GNRH1 PRPF19 PRPF19 CSRP3 CSRP3 UTP15 UTP15 WDR75 WDR75 MTREX MTREX FTSJ3 FTSJ3 AATF AATF UBB UBB ATP6 ATP6 CYTB CYTB RSL24D1 RSL24D1 LOC100515394 LOC100515394 NOP58 NOP58 RPS9 RPS9 WDR43 WDR43 DDX27 DDX27 BMS1 BMS1 I3LP71_PIG I3LP71_PIG RPS16 RPS16 PSMB3 PSMB3 LOC100515741 LOC100515741 PA2G4 PA2G4 AHCTF1 AHCTF1 GTF2H3 GTF2H3 GNL2 GNL2 INS INS ATP2A1 ATP2A1 RPS15 RPS15 ERCC3 ERCC3 TNNC2 TNNC2 TMEM38A TMEM38A AHSG AHSG LOC100623504 LOC100623504 CWC15 CWC15 NSA2 NSA2 RSRC1 RSRC1 NUP107 NUP107 UBE2V1 UBE2V1 NIP7 NIP7 PSMB6 PSMB6 RPF2 RPF2 NMD3 NMD3 TCEA1 TCEA1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
POLR2FRNA polymerase II subunit F. (127 aa)
DDX24DEAD-box helicase 24. (819 aa)
RPS11Ribosomal protein S11; Belongs to the universal ribosomal protein uS17 family. (158 aa)
DCAF13DDB1 and CUL4 associated factor 13. (444 aa)
WDR3WD repeat domain 3. (943 aa)
NOP56NOP56 ribonucleoprotein. (596 aa)
COX5BCytochrome c oxidase subunit 5B, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane [...] (129 aa)
DHX15Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15. (795 aa)
UGT2B31UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (529 aa)
FGBFibrinogen beta chain; Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re- epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However subsequent studies have shown that it i [...] (534 aa)
GNRH1GnRH-associated peptide 1; Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones; Belongs to the GnRH family. (91 aa)
PRPF19Pre-mRNA-processing factor 19. (504 aa)
CSRP3Uncharacterized protein. (200 aa)
UTP15Uncharacterized protein. (518 aa)
WDR75WD repeat-containing protein 75 isoform 1. (831 aa)
MTREXExosome RNA helicase MTR4. (1042 aa)
FTSJ3pre-rRNA processing protein FTSJ3; Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation. Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily. (836 aa)
AATFApoptosis antagonizing transcription factor. (569 aa)
UBBUbiquitin B. (229 aa)
ATP6ATP synthase subunit a; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subuni [...] (226 aa)
CYTBCytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis. (379 aa)
RSL24D1Ribosomal L24 domain containing 1. (163 aa)
LOC100515394UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (529 aa)
NOP58NOP58 ribonucleoprotein. (546 aa)
RPS940S ribosomal protein S9; Belongs to the universal ribosomal protein uS4 family. (194 aa)
WDR43WD repeat-containing protein 43. (681 aa)
DDX27DEAD-box helicase 27; Belongs to the DEAD box helicase family. (763 aa)
BMS1BMS1 ribosome biogenesis factor. (1284 aa)
I3LP71_PIGUDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (391 aa)
RPS1640S ribosomal protein S16; Belongs to the universal ribosomal protein uS9 family. (151 aa)
PSMB3Proteasome subunit beta. (205 aa)
LOC100515741UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (515 aa)
PA2G4Proliferation-associated 2G4. (372 aa)
AHCTF1AT-hook containing transcription factor 1. (2333 aa)
GTF2H3General transcription factor IIH subunit 3 isoform a. (321 aa)
GNL2Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily. (730 aa)
INSInsulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (108 aa)
ATP2A1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1021 aa)
RPS1540S ribosomal protein S15; Belongs to the universal ribosomal protein uS19 family. (145 aa)
ERCC3ERCC excision repair 3, TFIIH core complex helicase subunit. (801 aa)
TNNC2Troponin C, skeletal muscle; Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments. (211 aa)
TMEM38ATrimeric intracellular cation channel type A. (299 aa)
AHSGAlpha-2-HS-glycoprotein. (394 aa)
LOC100623504UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (430 aa)
CWC15CWC15 spliceosome associated protein homolog. (254 aa)
NSA2Ribosome biogenesis protein NSA2 homolog isoform 1. (260 aa)
RSRC1Arginine and serine rich coiled-coil 1. (334 aa)
NUP107Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (925 aa)
UBE2V1UBIQUITIN_CONJUGAT_2 domain-containing protein. (170 aa)
NIP760S ribosome subunit biogenesis protein NIP7 homolog; Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family. (192 aa)
PSMB6Uncharacterized protein. (334 aa)
RPF2Ribosome production factor 2 homolog. (306 aa)
NMD360S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. (525 aa)
TCEA1Transcription elongation factor A1. (293 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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