node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANGPTL1 | ANGPTL8 | ENSSSCP00000031577 | ENSSSCP00000038848 | Angiopoietin-related protein 1 isoform X1. | Angiopoietin-like protein 8. | 0.575 |
ANGPTL3 | ANGPTL4 | ENSSSCP00000004131 | ENSSSCP00000014452 | Fibrinogen C-terminal domain-containing protein. | Angiopoietin-related protein 4; Mediates inactivation of the lipoprotein lipase LPL, and thereby plays a role in the regulation of triglyceride clearance from the blood serum and in lipid metabolism. May also play a role in regulating glucose homeostasis and insulin sensitivity. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage (By similarity). Upon heterologous expression, inhibits the adhesion of endothelial cell to the extracellular matrix (ECM), and inhibits the reorganization of the actin cytoskeleton, formation of actin stre [...] | 0.920 |
ANGPTL3 | ANGPTL8 | ENSSSCP00000004131 | ENSSSCP00000038848 | Fibrinogen C-terminal domain-containing protein. | Angiopoietin-like protein 8. | 0.991 |
ANGPTL3 | GPIHBP1 | ENSSSCP00000004131 | ENSSSCP00000036748 | Fibrinogen C-terminal domain-containing protein. | Glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1. | 0.877 |
ANGPTL4 | ANGPTL3 | ENSSSCP00000014452 | ENSSSCP00000004131 | Angiopoietin-related protein 4; Mediates inactivation of the lipoprotein lipase LPL, and thereby plays a role in the regulation of triglyceride clearance from the blood serum and in lipid metabolism. May also play a role in regulating glucose homeostasis and insulin sensitivity. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage (By similarity). Upon heterologous expression, inhibits the adhesion of endothelial cell to the extracellular matrix (ECM), and inhibits the reorganization of the actin cytoskeleton, formation of actin stre [...] | Fibrinogen C-terminal domain-containing protein. | 0.920 |
ANGPTL4 | ANGPTL8 | ENSSSCP00000014452 | ENSSSCP00000038848 | Angiopoietin-related protein 4; Mediates inactivation of the lipoprotein lipase LPL, and thereby plays a role in the regulation of triglyceride clearance from the blood serum and in lipid metabolism. May also play a role in regulating glucose homeostasis and insulin sensitivity. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage (By similarity). Upon heterologous expression, inhibits the adhesion of endothelial cell to the extracellular matrix (ECM), and inhibits the reorganization of the actin cytoskeleton, formation of actin stre [...] | Angiopoietin-like protein 8. | 0.968 |
ANGPTL4 | GPIHBP1 | ENSSSCP00000014452 | ENSSSCP00000036748 | Angiopoietin-related protein 4; Mediates inactivation of the lipoprotein lipase LPL, and thereby plays a role in the regulation of triglyceride clearance from the blood serum and in lipid metabolism. May also play a role in regulating glucose homeostasis and insulin sensitivity. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage (By similarity). Upon heterologous expression, inhibits the adhesion of endothelial cell to the extracellular matrix (ECM), and inhibits the reorganization of the actin cytoskeleton, formation of actin stre [...] | Glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1. | 0.899 |
ANGPTL4 | PPARG | ENSSSCP00000014452 | ENSSSCP00000012339 | Angiopoietin-related protein 4; Mediates inactivation of the lipoprotein lipase LPL, and thereby plays a role in the regulation of triglyceride clearance from the blood serum and in lipid metabolism. May also play a role in regulating glucose homeostasis and insulin sensitivity. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage (By similarity). Upon heterologous expression, inhibits the adhesion of endothelial cell to the extracellular matrix (ECM), and inhibits the reorganization of the actin cytoskeleton, formation of actin stre [...] | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | 0.586 |
ANGPTL8 | ANGPTL1 | ENSSSCP00000038848 | ENSSSCP00000031577 | Angiopoietin-like protein 8. | Angiopoietin-related protein 1 isoform X1. | 0.575 |
ANGPTL8 | ANGPTL3 | ENSSSCP00000038848 | ENSSSCP00000004131 | Angiopoietin-like protein 8. | Fibrinogen C-terminal domain-containing protein. | 0.991 |
ANGPTL8 | ANGPTL4 | ENSSSCP00000038848 | ENSSSCP00000014452 | Angiopoietin-like protein 8. | Angiopoietin-related protein 4; Mediates inactivation of the lipoprotein lipase LPL, and thereby plays a role in the regulation of triglyceride clearance from the blood serum and in lipid metabolism. May also play a role in regulating glucose homeostasis and insulin sensitivity. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage (By similarity). Upon heterologous expression, inhibits the adhesion of endothelial cell to the extracellular matrix (ECM), and inhibits the reorganization of the actin cytoskeleton, formation of actin stre [...] | 0.968 |
ANGPTL8 | GPIHBP1 | ENSSSCP00000038848 | ENSSSCP00000036748 | Angiopoietin-like protein 8. | Glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1. | 0.907 |
GAPDH | GAPDHS | ENSSSCP00000035519 | ENSSSCP00000003110 | Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] | Glyceraldehyde-3-phosphate dehydrogenase. | 0.910 |
GAPDH | PPARG | ENSSSCP00000035519 | ENSSSCP00000012339 | Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | 0.775 |
GAPDHS | GAPDH | ENSSSCP00000003110 | ENSSSCP00000035519 | Glyceraldehyde-3-phosphate dehydrogenase. | Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] | 0.910 |
GAPDHS | PPARG | ENSSSCP00000003110 | ENSSSCP00000012339 | Glyceraldehyde-3-phosphate dehydrogenase. | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | 0.614 |
GPIHBP1 | ANGPTL3 | ENSSSCP00000036748 | ENSSSCP00000004131 | Glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1. | Fibrinogen C-terminal domain-containing protein. | 0.877 |
GPIHBP1 | ANGPTL4 | ENSSSCP00000036748 | ENSSSCP00000014452 | Glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1. | Angiopoietin-related protein 4; Mediates inactivation of the lipoprotein lipase LPL, and thereby plays a role in the regulation of triglyceride clearance from the blood serum and in lipid metabolism. May also play a role in regulating glucose homeostasis and insulin sensitivity. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage (By similarity). Upon heterologous expression, inhibits the adhesion of endothelial cell to the extracellular matrix (ECM), and inhibits the reorganization of the actin cytoskeleton, formation of actin stre [...] | 0.899 |
GPIHBP1 | ANGPTL8 | ENSSSCP00000036748 | ENSSSCP00000038848 | Glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1. | Angiopoietin-like protein 8. | 0.907 |
PPARG | ANGPTL4 | ENSSSCP00000012339 | ENSSSCP00000014452 | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | Angiopoietin-related protein 4; Mediates inactivation of the lipoprotein lipase LPL, and thereby plays a role in the regulation of triglyceride clearance from the blood serum and in lipid metabolism. May also play a role in regulating glucose homeostasis and insulin sensitivity. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage (By similarity). Upon heterologous expression, inhibits the adhesion of endothelial cell to the extracellular matrix (ECM), and inhibits the reorganization of the actin cytoskeleton, formation of actin stre [...] | 0.586 |