STRINGSTRING
DCT DCT TYRP1 TYRP1 TRPM1 TRPM1 SLC24A5 SLC24A5 TCL1A TCL1A CSPG4 CSPG4 SLC45A2 SLC45A2 METTL5 METTL5 DENND2B DENND2B COL6A1 COL6A1 MAP1B MAP1B TRMT11 TRMT11 PLEC PLEC TSPAN10 TSPAN10 FTO FTO METTL14 METTL14 MAML3 MAML3 METTL16 METTL16 WTAP WTAP ALKBH5 ALKBH5 MAML2 MAML2 ACTB ACTB TNRC18 TNRC18 YTHDF1 YTHDF1 TYR TYR ZCCHC4 ZCCHC4 COL6A3 COL6A3 MC1R MC1R COL6A2 COL6A2 KCNJ13 KCNJ13 PRG4 PRG4 ADAMTS6 ADAMTS6 ADAMTS9 ADAMTS9 MLANA MLANA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DCTL-dopachrome tautomerase; Catalyzes the conversion of L-dopachrome into 5,6- dihydroxyindole-2-carboxylic acid (DHICA). Involved in regulating eumelanin and phaeomelanin levels. (519 aa)
TYRP15,6-dihydroxyindole-2-carboxylic acid oxidase. (562 aa)
TRPM1Transient receptor potential cation channel subfamily M member 1. (1641 aa)
SLC24A5Solute carrier family 24 member 5; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (501 aa)
TCL1AUncharacterized protein. (54 aa)
CSPG4Chondroitin sulfate proteoglycan 4. (2319 aa)
SLC45A2Membrane-associated transporter protein; Melanocyte differentiation antigen. May transport substances required for melanin biosynthesis (By similarity); Belongs to the glycoside-pentoside-hexuronide (GPH) cation symporter transporter (TC 2.A.2) family. (566 aa)
METTL5Methyltransferase like 5. (226 aa)
DENND2BSuppression of tumorigenicity 5. (1132 aa)
COL6A1Collagen type VI alpha 1 chain. (1028 aa)
MAP1BMicrotubule-associated protein 1B isoform 1. (2474 aa)
TRMT11tRNA methyltransferase 11 homolog. (494 aa)
PLECPlectin. (5422 aa)
TSPAN10Tetraspanin. (391 aa)
FTOFTO_NTD domain-containing protein. (509 aa)
METTL14N6-adenosine-methyltransferase non-catalytic subunit; Belongs to the MT-A70-like family. (456 aa)
MAML3Mastermind like transcriptional coactivator 3. (1113 aa)
METTL16U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that methylates adenosine residues of a subset of RNAs and plays a key role in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6- methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure. In presence of S-adenosyl-L-methionine, binds the 3'-UTR region of MAT2A mRNA and specifical [...] (561 aa)
WTAPUncharacterized protein. (649 aa)
ALKBH5AlkB homolog 5, RNA demethylase. (394 aa)
MAML2Mastermind like transcriptional coactivator 2. (1117 aa)
ACTBActin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (375 aa)
TNRC18Trinucleotide repeat containing 18. (2426 aa)
YTHDF1YTH N6-methyladenosine RNA binding protein 1. (652 aa)
TYRTyrosinase. (531 aa)
ZCCHC4Zinc finger CCHC domain-containing protein 4 isoform 1. (513 aa)
COL6A3Collagen type VI alpha 3 chain. (2911 aa)
MC1RMelanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a role in the regulation of eumelanin (black/brown) and phaeomelanin (red/yellow) synthesis; Belongs to the G-protein coupled receptor 1 family. (320 aa)
COL6A2Collagen type VI alpha 2 chain. (943 aa)
KCNJ13Potassium voltage-gated channel subfamily J member 13. (360 aa)
PRG4Uncharacterized protein. (370 aa)
ADAMTS6A disintegrin and metalloproteinase with thrombospondin motifs 6 isoform X1. (1117 aa)
ADAMTS9ADAM metallopeptidase with thrombospondin type 1 motif 9. (2020 aa)
MLANAMelanoma antigen recognized by T-cells 1. (118 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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