node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALKBH5 | METTL14 | ENSSSCP00000038766 | ENSSSCP00000046701 | AlkB homolog 5, RNA demethylase. | N6-adenosine-methyltransferase non-catalytic subunit; Belongs to the MT-A70-like family. | 0.953 |
ALKBH5 | YTHDF2 | ENSSSCP00000038766 | ENSSSCP00000065604 | AlkB homolog 5, RNA demethylase. | YTH N6-methyladenosine RNA binding protein 2. | 0.913 |
EGF | FGF2 | ENSSSCP00000028117 | ENSSSCP00000055271 | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity). | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | 0.939 |
EGF | TP53 | ENSSSCP00000028117 | ENSSSCP00000050664 | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity). | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] | 0.743 |
FGF2 | EGF | ENSSSCP00000055271 | ENSSSCP00000028117 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity). | 0.939 |
FGF2 | TP53 | ENSSSCP00000055271 | ENSSSCP00000050664 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] | 0.550 |
FGF2 | WNT5A | ENSSSCP00000055271 | ENSSSCP00000037791 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.475 |
FOXN1 | WNT5A | ENSSSCP00000018821 | ENSSSCP00000037791 | Forkhead box N1. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.478 |
HMGA2 | TP53 | ENSSSCP00000061245 | ENSSSCP00000050664 | Uncharacterized protein. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] | 0.603 |
METTL14 | ALKBH5 | ENSSSCP00000046701 | ENSSSCP00000038766 | N6-adenosine-methyltransferase non-catalytic subunit; Belongs to the MT-A70-like family. | AlkB homolog 5, RNA demethylase. | 0.953 |
METTL14 | YTHDF2 | ENSSSCP00000046701 | ENSSSCP00000065604 | N6-adenosine-methyltransferase non-catalytic subunit; Belongs to the MT-A70-like family. | YTH N6-methyladenosine RNA binding protein 2. | 0.943 |
TP53 | EGF | ENSSSCP00000050664 | ENSSSCP00000028117 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6 (By similarity). | 0.743 |
TP53 | FGF2 | ENSSSCP00000050664 | ENSSSCP00000055271 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | 0.550 |
TP53 | HMGA2 | ENSSSCP00000050664 | ENSSSCP00000061245 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] | Uncharacterized protein. | 0.603 |
WNT5A | FGF2 | ENSSSCP00000037791 | ENSSSCP00000055271 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | 0.475 |
WNT5A | FOXN1 | ENSSSCP00000037791 | ENSSSCP00000018821 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | Forkhead box N1. | 0.478 |
YTHDF2 | ALKBH5 | ENSSSCP00000065604 | ENSSSCP00000038766 | YTH N6-methyladenosine RNA binding protein 2. | AlkB homolog 5, RNA demethylase. | 0.913 |
YTHDF2 | METTL14 | ENSSSCP00000065604 | ENSSSCP00000046701 | YTH N6-methyladenosine RNA binding protein 2. | N6-adenosine-methyltransferase non-catalytic subunit; Belongs to the MT-A70-like family. | 0.943 |