20 items (Sus scrofa) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Predicted Interactions

gene neighborhood

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Your Input:
	METTL14	N6-adenosine-methyltransferase non-catalytic subunit; Belongs to the MT-A70-like family. (456 aa)
	PPARA	Uncharacterized protein. (469 aa)
	LDHB	L-lactate dehydrogenase B chain; Belongs to the LDH/MDH superfamily. LDH family. (377 aa)
	ARG2	Arginase. (354 aa)
	MTOR	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2548 aa)
	ACAA2	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (398 aa)
	PPARG	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (528 aa)
	CTNNB1	Catenin beta 1. (808 aa)
	ACTB	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (375 aa)
	ALKBH5	AlkB homolog 5, RNA demethylase. (394 aa)
	WTAP	Uncharacterized protein. (649 aa)
	TRAF4	TNF receptor-associated factor. (470 aa)
	ECH1	Enoyl-CoA hydratase 1; Belongs to the enoyl-CoA hydratase/isomerase family. (368 aa)
	ACSL1	Acyl-CoA synthetase long chain family member 1. (771 aa)
	ACSBG2	Acyl-CoA synthetase bubblegum family member 2. (674 aa)
	FTO	FTO_NTD domain-containing protein. (509 aa)
	PRMT6	Protein arginine methyltransferase 6; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (375 aa)
	CYP1B1	Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (543 aa)
	LDHB-2	L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (334 aa)
	BCAT1	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (436 aa)

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACAA2	ACSL1	ENSSSCP00000004865	ENSSSCP00000043771	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Acyl-CoA synthetase long chain family member 1.	0.546
ACAA2	ECH1	ENSSSCP00000004865	ENSSSCP00000042283	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Enoyl-CoA hydratase 1; Belongs to the enoyl-CoA hydratase/isomerase family.	0.625
ACSL1	ACAA2	ENSSSCP00000043771	ENSSSCP00000004865	Acyl-CoA synthetase long chain family member 1.	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.546
ACSL1	PPARA	ENSSSCP00000043771	ENSSSCP00000000007	Acyl-CoA synthetase long chain family member 1.	Uncharacterized protein.	0.608
ACSL1	PPARG	ENSSSCP00000043771	ENSSSCP00000012339	Acyl-CoA synthetase long chain family member 1.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.747
ACTB	ARG2	ENSSSCP00000035521	ENSSSCP00000002491	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Arginase.	0.461
ACTB	CTNNB1	ENSSSCP00000035521	ENSSSCP00000031836	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Catenin beta 1.	0.705
ACTB	CYP1B1	ENSSSCP00000035521	ENSSSCP00000056236	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family.	0.456
ACTB	MTOR	ENSSSCP00000035521	ENSSSCP00000003699	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.	0.516
ACTB	PPARA	ENSSSCP00000035521	ENSSSCP00000000007	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Uncharacterized protein.	0.564
ACTB	PPARG	ENSSSCP00000035521	ENSSSCP00000012339	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.979
ALKBH5	FTO	ENSSSCP00000038766	ENSSSCP00000047110	AlkB homolog 5, RNA demethylase.	FTO_NTD domain-containing protein.	0.979
ALKBH5	METTL14	ENSSSCP00000038766	ENSSSCP00000046701	AlkB homolog 5, RNA demethylase.	N6-adenosine-methyltransferase non-catalytic subunit; Belongs to the MT-A70-like family.	0.953
ALKBH5	WTAP	ENSSSCP00000038766	ENSSSCP00000039764	AlkB homolog 5, RNA demethylase.	Uncharacterized protein.	0.975
ARG2	ACTB	ENSSSCP00000002491	ENSSSCP00000035521	Arginase.	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	0.461
CTNNB1	ACTB	ENSSSCP00000031836	ENSSSCP00000035521	Catenin beta 1.	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	0.705
CTNNB1	PPARA	ENSSSCP00000031836	ENSSSCP00000000007	Catenin beta 1.	Uncharacterized protein.	0.480
CTNNB1	PPARG	ENSSSCP00000031836	ENSSSCP00000012339	Catenin beta 1.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.797
CYP1B1	ACTB	ENSSSCP00000056236	ENSSSCP00000035521	Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family.	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	0.456
ECH1	ACAA2	ENSSSCP00000042283	ENSSSCP00000004865	Enoyl-CoA hydratase 1; Belongs to the enoyl-CoA hydratase/isomerase family.	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.625