STRINGSTRING
PIAS1 PIAS1 VIRMA VIRMA PIAS3 PIAS3 DDB1 DDB1 SKP2 SKP2 ISG20 ISG20 SAMHD1 SAMHD1 SRC SRC YTHDF1 YTHDF1 CUL1 CUL1 ALKBH5 ALKBH5 WTAP WTAP MYC MYC HNRNPA2B1 HNRNPA2B1 SUMO3 SUMO3 CDK1 CDK1 METTL14 METTL14 FTO FTO YTHDF3 YTHDF3 YTHDC1 YTHDC1 SAE1 SAE1 YTHDF2 YTHDF2 CUL4A CUL4A EGFR EGFR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PIAS1Protein inhibitor of activated STAT 1. (685 aa)
VIRMAVir like m6A methyltransferase associated. (1812 aa)
PIAS3Protein inhibitor of activated STAT 3. (628 aa)
DDB1Damage specific DNA binding protein 1. (1139 aa)
SKP2S-phase kinase-associated protein 2 isoform 1. (436 aa)
ISG20Interferon stimulated exonuclease gene 20. (189 aa)
SAMHD1SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1. (627 aa)
SRCTyrosine-protein kinase. (559 aa)
YTHDF1YTH N6-methyladenosine RNA binding protein 1. (652 aa)
CUL1Cullin 1; Belongs to the cullin family. (802 aa)
ALKBH5AlkB homolog 5, RNA demethylase. (394 aa)
WTAPUncharacterized protein. (649 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity). (452 aa)
HNRNPA2B1Heterogeneous nuclear ribonucleoprotein A2/B1. (369 aa)
SUMO3Small ubiquitin-related modifier. (101 aa)
CDK1Cyclin-dependent kinase 1 isoform 1; Belongs to the protein kinase superfamily. (297 aa)
METTL14N6-adenosine-methyltransferase non-catalytic subunit; Belongs to the MT-A70-like family. (456 aa)
FTOFTO_NTD domain-containing protein. (509 aa)
YTHDF3YTH domain-containing family protein 3 isoform b. (588 aa)
YTHDC1YTH domain containing 1. (743 aa)
SAE1SUMO1 activating enzyme subunit 1. (385 aa)
YTHDF2YTH N6-methyladenosine RNA binding protein 2. (600 aa)
CUL4ACullin 4A; Belongs to the cullin family. (712 aa)
EGFRReceptor protein-tyrosine kinase. (1205 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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