STRINGSTRING
VWF VWF OTOGL OTOGL CCN3 CCN3 SLIT2 SLIT2 SLIT1 SLIT1 SLIT3 SLIT3 NDP NDP OTOG OTOG GREM2 GREM2 NBL1 NBL1 CER1 CER1 CCN2 CCN2 GREM1 GREM1 MUC5AC MUC5AC CCN4 CCN4 CCN6 CCN6 CCN1 CCN1 MUC2 MUC2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
VWFVon Willebrand factor; Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet- surface receptor complex, glycoprotein Ibalpha/IX/V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma (By similarity). (2940 aa)
OTOGLOtogelin like. (2353 aa)
CCN3Cellular communication network factor 3. (398 aa)
SLIT2Slit guidance ligand 2. (1542 aa)
SLIT1Slit guidance ligand 1. (1534 aa)
SLIT3Slit guidance ligand 3. (1523 aa)
NDPNorrin cystine knot growth factor NDP. (133 aa)
OTOGOtogelin. (2863 aa)
GREM2Gremlin 2, DAN family BMP antagonist. (166 aa)
NBL1CTCK domain-containing protein. (364 aa)
CER1Cerberus 1, DAN family BMP antagonist. (273 aa)
CCN2CCN family member 2; Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes (By similarity). Mediates heparin- and divalent cation- dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells (By similarity). Enhances fibroblast growth factor-induced DNA synthesis (By similarity). (354 aa)
GREM1Gremlin 1, DAN family BMP antagonist. (240 aa)
MUC5ACUncharacterized protein. (3330 aa)
CCN4WNT1-inducible-signaling pathway protein 1 isoform X1. (371 aa)
CCN6WNT1-inducible-signaling pathway protein 3 isoform 3. (354 aa)
CCN1Cellular communication network factor 1. (382 aa)
MUC2Uncharacterized protein. (3289 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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