STRINGSTRING
SYT5 SYT5 C2CD4D C2CD4D CPNE1 CPNE1 PKN2 PKN2 RPGRIP1L RPGRIP1L RASAL2 RASAL2 UVRAG UVRAG PRKCB PRKCB SYT4 SYT4 PLCB4 PLCB4 PLCL1 PLCL1 TOLLIP TOLLIP CPNE2 CPNE2 SYT6 SYT6 LOC100525027 LOC100525027 PLCH2 PLCH2 ITCH ITCH HECW1 HECW1 BCR BCR MCTP2 MCTP2 RASA3 RASA3 UNC13A UNC13A CPNE5 CPNE5 CADPS2 CADPS2 FER1L6 FER1L6 SMURF2 SMURF2 PLCE1 PLCE1 SYT13 SYT13 RAB11FIP1 RAB11FIP1 SYT7 SYT7 PKN1 PKN1 C2CD5 C2CD5 PRF1 PRF1 DOC2A DOC2A SYT11 SYT11 RIMS3 RIMS3 SYT17 SYT17 CPNE3 CPNE3 CEP120 CEP120 PLCL2 PLCL2 PIK3CA PIK3CA PLA2G4E PLA2G4E PRKCD PRKCD ESYT2 ESYT2 DOC2B DOC2B UNC13C UNC13C RAB11FIP2 RAB11FIP2 PLCH1 PLCH1 C2CD4C C2CD4C SYNGAP1 SYNGAP1 MYOF MYOF PLA2G4A PLA2G4A OTOF OTOF PLCB2 PLCB2 ABR ABR PLCD4 PLCD4 RASA2 RASA2 CC2D2B CC2D2B RIMS2 RIMS2 MCTP1 MCTP1 ESYT1 ESYT1 SMURF1 SMURF1 CADPS CADPS DYSF DYSF UNC13B UNC13B RAB11FIP5 RAB11FIP5 PLCB1 PLCB1 LOC100625711 LOC100625711 RIMS1 RIMS1 BAIAP3 BAIAP3 RPH3A RPH3A CC2D1A CC2D1A ITSN2 ITSN2 RASA1 RASA1 SYTL1 SYTL1 WWP1 WWP1 SYTL5 SYTL5 SYT10 SYT10 PLCZ1 PLCZ1 SYT1 SYT1 CCDC33 CCDC33 CPNE6 CPNE6 TC2N TC2N PLCG2 PLCG2 SYT3 SYT3 PRKCG PRKCG SYTL3 SYTL3 PLA2G4F PLA2G4F PLA2G4D PLA2G4D JMJD7 JMJD7 SYT16 SYT16 DAB2IP DAB2IP SYDE2 SYDE2 PLCG1 PLCG1 INPP4A INPP4A PRKCE PRKCE CC2D2A CC2D2A RASAL1 RASAL1 SYT2 SYT2 CPNE4 CPNE4 MTMR14 MTMR14 SYTL4 SYTL4 CAPN6 CAPN6 PLCB3 PLCB3 SYT9 SYT9 C2CD3 C2CD3 CAPN5 CAPN5 SYTL2 SYTL2 PIK3C2B PIK3C2B SYT14 SYT14 UNC13D UNC13D PRKCA PRKCA PLCD3 PLCD3 PLCD1 PLCD1 ESYT3 ESYT3 C2CD2 C2CD2 RASA4B RASA4B CPNE8 CPNE8 SYT8 SYT8 PCLO PCLO WWP2 WWP2 CC2D1B CC2D1B SYT12 SYT12 PIK3C2A PIK3C2A RIMS4 RIMS4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SYT5Synaptotagmin 5. (385 aa)
C2CD4DC2 calcium dependent domain containing 4D. (353 aa)
CPNE1Uncharacterized protein. (1136 aa)
PKN2Serine/threonine-protein kinase N2 isoform 1. (983 aa)
RPGRIP1LProtein fantom isoform X1. (1270 aa)
RASAL2RAS protein activator like 2. (1279 aa)
UVRAGUV radiation resistance associated. (748 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
SYT4Synaptotagmin 4. (425 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
PLCL1Phosphoinositide phospholipase C. (1096 aa)
TOLLIPCUE domain-containing protein. (272 aa)
CPNE2Copine 2. (580 aa)
SYT6Synaptotagmin 6. (532 aa)
LOC100525027Uncharacterized protein. (376 aa)
PLCH2Phosphoinositide phospholipase C. (1329 aa)
ITCHE3 ubiquitin-protein ligase. (873 aa)
HECW1HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1. (1602 aa)
BCRBCR activator of RhoGEF and GTPase. (1274 aa)
MCTP2Multiple C2 and transmembrane domain-containing protein 2 isoform X3. (912 aa)
RASA3RAS p21 protein activator 3. (874 aa)
UNC13AUncharacterized protein. (1581 aa)
CPNE5Copine 5. (610 aa)
CADPS2Calcium dependent secretion activator 2. (1297 aa)
FER1L6Fer-1 like family member 6. (1858 aa)
SMURF2E3 ubiquitin-protein ligase. (748 aa)
PLCE1Phosphoinositide phospholipase C. (2316 aa)
SYT13Synaptotagmin-13 isoform 1. (426 aa)
RAB11FIP1Uncharacterized protein. (642 aa)
SYT7Synaptotagmin-7 isoform X2. (686 aa)
PKN1Protein kinase N1. (956 aa)
C2CD5C2 calcium dependent domain containing 5. (1148 aa)
PRF1Perforin 1. (555 aa)
DOC2ADouble C2 domain alpha. (487 aa)
SYT11Synaptotagmin 11. (438 aa)
RIMS3Regulating synaptic membrane exocytosis 3. (312 aa)
SYT17Synaptotagmin 17. (505 aa)
CPNE3Copine 3. (571 aa)
CEP120Centrosomal protein 120. (992 aa)
PLCL2Phosphoinositide phospholipase C. (1128 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
PLA2G4EPhospholipase A2. (872 aa)
PRKCDProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (723 aa)
ESYT2Extended synaptotagmin 2. (863 aa)
DOC2BDouble C2-like domain-containing protein. (412 aa)
UNC13CUnc-13 homolog C. (2214 aa)
RAB11FIP2Rab11 family-interacting protein 2 isoform 1. (512 aa)
PLCH1Phosphoinositide phospholipase C. (1690 aa)
C2CD4CC2 calcium dependent domain containing 4C. (420 aa)
SYNGAP1Synaptic Ras GTPase activating protein 1. (1293 aa)
MYOFMyoferlin. (2182 aa)
PLA2G4APhospholipase A2. (758 aa)
OTOFOtoferlin. (1997 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
ABRABR activator of RhoGEF and GTPase. (964 aa)
PLCD41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4; Hydrolyzes the phosphatidylinositol 4,5-bisphosphate (PIP2) to generate 2 second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). DAG mediates the activation of protein kinase C (PKC), while IP3 releases Ca(2+) from intracellular stores. Required for acrosome reaction in sperm during fertilization, probably by acting as an important enzyme for intracellular Ca(2+) mobilization in the zona pellucida-induced acrosome reaction. May play a role in cell growth. Modulates the liver regeneration [...] (797 aa)
RASA2RAS p21 protein activator 2. (854 aa)
CC2D2BC2 domain-containing protein. (1442 aa)
RIMS2Regulating synaptic membrane exocytosis 2. (1348 aa)
MCTP1Multiple C2 and transmembrane domain containing 1. (995 aa)
ESYT1Extended synaptotagmin 1. (1109 aa)
SMURF1E3 ubiquitin-protein ligase. (859 aa)
CADPSUncharacterized protein. (1370 aa)
DYSFDysferlin. (2119 aa)
UNC13BUncharacterized protein. (4266 aa)
RAB11FIP5Uncharacterized protein. (1391 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1173 aa)
LOC100625711Uncharacterized protein. (511 aa)
RIMS1Regulating synaptic membrane exocytosis 1. (1684 aa)
BAIAP3BAI1 associated protein 3. (1345 aa)
RPH3ARabphilin-3A isoform 1. (701 aa)
CC2D1ACoiled-coil and C2 domain containing 1A. (981 aa)
ITSN2Intersectin 2. (1695 aa)
RASA1RAS p21 protein activator 1. (1040 aa)
SYTL1Synaptotagmin like 1. (602 aa)
WWP1E3 ubiquitin-protein ligase. (923 aa)
SYTL5Synaptotagmin-like protein 5 isoform X1. (754 aa)
SYT10Synaptotagmin-10. (523 aa)
PLCZ11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. In vitro, hydrolyzes PtdIns(4,5)P2 in a Ca(2+)-dependent manner. Triggers intracellular Ca(2+) oscillations in oocytes solely during M phase and is involved in inducing oocyte activation and initiating embryonic development up to the blastocyst stage. Is therefore a strong candidate for the egg-activating soluble sperm factor that is t [...] (639 aa)
SYT1Synaptotagmin 1. (379 aa)
CCDC33Coiled-coil domain containing 33. (740 aa)
CPNE6Copine 6. (556 aa)
TC2NTandem C2 domains nuclear protein isoform 1. (490 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
SYT3Synaptotagmin-3 isoform X1. (591 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (759 aa)
SYTL3Synaptotagmin like 3. (610 aa)
PLA2G4FPhospholipase A2. (852 aa)
PLA2G4DPhospholipase A2. (812 aa)
JMJD7Phospholipase A2. (780 aa)
SYT16Synaptotagmin 16. (645 aa)
DAB2IPDAB2 interacting protein. (1196 aa)
SYDE2Synapse defective Rho GTPase homolog 2. (1190 aa)
PLCG1Phosphoinositide phospholipase C. (1379 aa)
INPP4AInositol polyphosphate-4-phosphatase type I A. (976 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa)
CC2D2ACoiled-coil and C2 domain containing 2A. (1618 aa)
RASAL1RAS protein activator like 1. (784 aa)
SYT2Synaptotagmin 2. (417 aa)
CPNE4Copine-4 isoform 1. (575 aa)
MTMR14Myotubularin related protein 14. (728 aa)
SYTL4Synaptotagmin like 4. (721 aa)
CAPN6Calpain 6; Belongs to the peptidase C2 family. (624 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1233 aa)
SYT9Synaptotagmin-9. (491 aa)
C2CD3C2 domain containing 3 centriole elongation regulator. (2353 aa)
CAPN5Calpain 5; Belongs to the peptidase C2 family. (692 aa)
SYTL2Synaptotagmin like 2. (906 aa)
PIK3C2BPhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta; Belongs to the PI3/PI4-kinase family. (1634 aa)
SYT14Synaptotagmin 14. (801 aa)
UNC13DUnc-13 homolog D. (1090 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (669 aa)
PLCD3Phosphoinositide phospholipase C. (784 aa)
PLCD1Phosphoinositide phospholipase C. (724 aa)
ESYT3Extended synaptotagmin 3. (889 aa)
C2CD2C2 calcium dependent domain containing 2. (709 aa)
RASA4BUncharacterized protein. (882 aa)
CPNE8Copine-8. (577 aa)
SYT8Synaptotagmin 8. (381 aa)
PCLOPiccolo presynaptic cytomatrix protein. (5107 aa)
WWP2E3 ubiquitin-protein ligase. (895 aa)
CC2D1BCoiled-coil and C2 domain containing 1B. (863 aa)
SYT12Synaptotagmin-12 isoform X3. (421 aa)
PIK3C2APhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family. (1669 aa)
RIMS4Regulating synaptic membrane exocytosis 4. (269 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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