STRINGSTRING
HIST1H3E HIST1H3E IL2RG IL2RG STAT3 STAT3 PIK3R1 PIK3R1 IL7R IL7R JAK3 JAK3 SMARCA4 SMARCA4 JAK1 JAK1 A0A286ZRB3_PIG A0A286ZRB3_PIG BRWD1 BRWD1 CRLF2 CRLF2 IRS2 IRS2 LOC100511937 LOC100511937 PIK3R2 PIK3R2 IRS1 IRS1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HIST1H3EHistone H3; Belongs to the histone H3 family. (136 aa)
IL2RGCytokine receptor common subunit gamma. (395 aa)
STAT3Signal transducer and activator of transcription 3; Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF, LEP and other growth factors. Once activated, recruits coactivators, such as NCOA1 or MED1, to the promoter region of the target gene. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA (By similarity). Acts as a regulator of inflammatory response by regul [...] (772 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (766 aa)
IL7RFibronectin type-III domain-containing protein. (458 aa)
JAK3Tyrosine-protein kinase. (1103 aa)
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. (1647 aa)
JAK1Tyrosine-protein kinase. (1154 aa)
A0A286ZRB3_PIGHistone domain-containing protein. (130 aa)
BRWD1Bromodomain and WD repeat domain containing 1. (2325 aa)
CRLF2Cytokine receptor-like factor 2. (368 aa)
IRS2Insulin receptor substrate 2. (1092 aa)
LOC100511937Uncharacterized protein. (532 aa)
PIK3R2Uncharacterized protein. (772 aa)
IRS1Insulin receptor substrate 1. (1241 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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