88 items (Sus scrofa) - STRING interaction network

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Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

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protein homology

Your Input:
	KCNJ4	Potassium voltage-gated channel subfamily J member 4. (447 aa)
	GNB3	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 isoform 1. (340 aa)
	KCNA1	Potassium voltage-gated channel subfamily A member 1; Belongs to the potassium channel family. (495 aa)
	KCNK17	Potassium two pore domain channel subfamily K member 17; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (326 aa)
	HCN4	Hyperpolarization activated cyclic nucleotide gated potassium channel 4. (1199 aa)
	KCNK13	Potassium two pore domain channel subfamily K member 13; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (410 aa)
	KCNN4	Intermediate conductance calcium-activated potassium channel protein 4. (426 aa)
	KCNJ14	Potassium voltage-gated channel subfamily J member 14. (434 aa)
	KCNA7	Potassium voltage-gated channel subfamily A member 7; Belongs to the potassium channel family. (451 aa)
	KCNQ4	Potassium voltage-gated channel subfamily Q member 4; Belongs to the potassium channel family. (695 aa)
	KCNV2	Potassium voltage-gated channel modifier subfamily V member 2; Belongs to the potassium channel family. (560 aa)
	KCNG2	Potassium voltage-gated channel modifier subfamily G member 2; Belongs to the potassium channel family. (478 aa)
	KCNV1	Potassium voltage-gated channel modifier subfamily V member 1; Belongs to the potassium channel family. (502 aa)
	KCNB2	Potassium voltage-gated channel subfamily B member 2; Belongs to the potassium channel family. (912 aa)
	HCN3	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3. (784 aa)
	KCNN3	Small conductance calcium-activated potassium channel protein 3; Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. The channel is blocked by apamin (By similarity). (718 aa)
	KCND3	Potassium voltage-gated channel subfamily D member 3; Belongs to the potassium channel family. (655 aa)
	KCNC4	Potassium voltage-gated channel subfamily C member 4; Belongs to the potassium channel family. (662 aa)
	KCNG1	Potassium voltage-gated channel subfamily G member 1 isoform X1; Belongs to the potassium channel family. (514 aa)
	GNB2	G protein subunit beta 2. (340 aa)
	GNG13	G protein subunit gamma 13. (67 aa)
	KCNG3	Potassium voltage-gated channel modifier subfamily G member 3; Belongs to the potassium channel family. (436 aa)
	KCNK1	Potassium channel subfamily K member. (336 aa)
	KCNK7	Potassium channel subfamily K member. (307 aa)
	KCNK4	Potassium two pore domain channel subfamily K member 4; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (394 aa)
	KCNA4	Potassium voltage-gated channel subfamily A member 4; Belongs to the potassium channel family. (595 aa)
	ABCC8	ATP binding cassette subfamily C member 8. (1581 aa)
	KCNN2	Small conductance calcium-activated potassium channel protein 2 isoform X1. (851 aa)
	KCNJ1	Potassium voltage-gated channel subfamily J member 1. (384 aa)
	GNGT1	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (89 aa)
	KCNJ5	G protein-activated inward rectifier potassium channel 4; This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by external barium. (419 aa)
	KCNH3	Potassium voltage-gated channel subfamily H member 3. (1081 aa)
	HCN1	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1. (885 aa)
	GNG2	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (248 aa)
	GNG8	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
	KCNG4	Potassium voltage-gated channel modifier subfamily G member 4; Belongs to the potassium channel family. (508 aa)
	KCNS1	Potassium voltage-gated channel modifier subfamily S member 1; Belongs to the potassium channel family. (568 aa)
	KCNH4	Potassium voltage-gated channel subfamily H member 4. (1017 aa)
	KCNH7	Potassium voltage-gated channel subfamily H member 7. (1198 aa)
	GNB5	G protein subunit beta 5. (420 aa)
	KCNF1	Potassium voltage-gated channel modifier subfamily F member 1; Belongs to the potassium channel family. (504 aa)
	GNG3	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (240 aa)
	KCNK3	Potassium channel subfamily K member. (401 aa)
	KCNC2	Potassium voltage-gated channel subfamily C member 2; Belongs to the potassium channel family. (677 aa)
	KCND2	Potassium voltage-gated channel subfamily D member 2; Belongs to the potassium channel family. (630 aa)
	KCNK2	Potassium two pore domain channel subfamily K member 2; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (452 aa)
	GNB4	G protein subunit beta 4. (340 aa)
	KCNJ12	ATP-sensitive inward rectifier potassium channel 12 isoform X1. (429 aa)
	KCNK16	Potassium two pore domain channel subfamily K member 16; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (294 aa)
	ABCC9	ATP binding cassette subfamily C member 9. (1603 aa)
	KCNH1	Uncharacterized protein. (919 aa)
	A0A287ACS9_PIG	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (65 aa)
	LOC110255211	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (125 aa)
	KCNQ5	Potassium voltage-gated channel subfamily Q member 5. (941 aa)
	KCNK10	Potassium two pore domain channel subfamily K member 10; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (538 aa)
	HCN2	Hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2. (897 aa)
	KCNQ2	Potassium voltage-gated channel subfamily Q member 2; Belongs to the potassium channel family. (949 aa)
	KCNAB2	Potassium voltage-gated channel subfamily A regulatory beta subunit 2. (415 aa)
	KCNK6	Potassium two pore domain channel subfamily K member 6; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (495 aa)
	GNB1	G protein subunit beta 1. (395 aa)
	KCNA10	Potassium voltage-gated channel subfamily A member 10; Belongs to the potassium channel family. (511 aa)
	KCNK9	Potassium channel subfamily K member. (374 aa)
	KCNA2	Potassium voltage-gated channel, shaker-related subfamily, member 2; Belongs to the potassium channel family. (499 aa)
	KCNH5	Potassium voltage-gated channel subfamily H member 5. (988 aa)
	KCNJ8	Potassium voltage-gated channel subfamily J member 8. (424 aa)
	KCNJ10	Potassium voltage-gated channel subfamily J member 10. (379 aa)
	KCNAB3	Potassium voltage-gated channel subfamily A regulatory beta subunit 3. (338 aa)
	KCNC1	Potassium voltage-gated channel subfamily C member 1; Belongs to the potassium channel family. (585 aa)
	KCNH8	Potassium voltage-gated channel subfamily H member 8. (1107 aa)
	KCNN1	Potassium calcium-activated channel subfamily N member 1. (623 aa)
	KCNJ6	Potassium voltage-gated channel subfamily J member 6. (441 aa)
	KCNJ2	Inward rectifier potassium channel 2; Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be bl [...] (427 aa)
	KCNJ15	Potassium voltage-gated channel subfamily J member 15. (375 aa)
	GABBR2	Gamma-aminobutyric acid type B receptor subunit 2. (958 aa)
	KCNH6	Potassium voltage-gated channel subfamily H member 6. (993 aa)
	KCNJ11	Potassium voltage-gated channel subfamily J member 11. (388 aa)
	KCNJ3	Potassium voltage-gated channel subfamily J member 3. (501 aa)
	KCNAB1	Potassium voltage-gated channel subfamily A member regulatory beta subunit 1. (419 aa)
	KCNS3	Potassium voltage-gated channel subfamily S member 3 isoform X1; Belongs to the potassium channel family. (491 aa)
	KCNS2	Potassium voltage-gated channel modifier subfamily S member 2; Belongs to the potassium channel family. (529 aa)
	KCNA3	Potassium voltage-gated channel subfamily A member 3; Belongs to the potassium channel family. (588 aa)
	KCND1	Potassium voltage-gated channel subfamily D member 1; Belongs to the potassium channel family. (648 aa)
	KCNC3	Potassium voltage-gated channel subfamily C member 3; Belongs to the potassium channel family. (815 aa)
	KCNJ9	Potassium voltage-gated channel subfamily J member 9. (505 aa)
	LOC100621431	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (234 aa)
	KCNJ16	Potassium voltage-gated channel subfamily J member 16. (419 aa)
	GABBR1	Gamma-aminobutyric acid type B receptor subunit 1. (1247 aa)
	GNG10	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A287ACS9_PIG	GABBR1	ENSSSCP00000041693	ENSSSCP00000070651	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Gamma-aminobutyric acid type B receptor subunit 1.	0.560
A0A287ACS9_PIG	GABBR2	ENSSSCP00000041693	ENSSSCP00000061213	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Gamma-aminobutyric acid type B receptor subunit 2.	0.545
A0A287ACS9_PIG	GNB1	ENSSSCP00000041693	ENSSSCP00000048402	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	G protein subunit beta 1.	0.805
A0A287ACS9_PIG	GNB2	ENSSSCP00000041693	ENSSSCP00000008190	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	G protein subunit beta 2.	0.865
A0A287ACS9_PIG	GNB3	ENSSSCP00000041693	ENSSSCP00000000727	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 isoform 1.	0.984
A0A287ACS9_PIG	GNB4	ENSSSCP00000041693	ENSSSCP00000036910	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	G protein subunit beta 4.	0.851
A0A287ACS9_PIG	GNB5	ENSSSCP00000041693	ENSSSCP00000031679	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	G protein subunit beta 5.	0.987
A0A287ACS9_PIG	GNG10	ENSSSCP00000041693	ENSSSCP00000072165	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.439
A0A287ACS9_PIG	GNG13	ENSSSCP00000041693	ENSSSCP00000008555	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	G protein subunit gamma 13.	0.629
A0A287ACS9_PIG	GNG2	ENSSSCP00000041693	ENSSSCP00000024099	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.540
A0A287ACS9_PIG	GNG3	ENSSSCP00000041693	ENSSSCP00000032340	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.400
A0A287ACS9_PIG	GNG8	ENSSSCP00000041693	ENSSSCP00000025202	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.540
A0A287ACS9_PIG	GNGT1	ENSSSCP00000041693	ENSSSCP00000016250	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.688
A0A287ACS9_PIG	KCNJ10	ENSSSCP00000041693	ENSSSCP00000052657	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Potassium voltage-gated channel subfamily J member 10.	0.531
A0A287ACS9_PIG	KCNJ12	ENSSSCP00000041693	ENSSSCP00000039219	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	ATP-sensitive inward rectifier potassium channel 12 isoform X1.	0.531
A0A287ACS9_PIG	KCNJ15	ENSSSCP00000041693	ENSSSCP00000059698	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Potassium voltage-gated channel subfamily J member 15.	0.531
A0A287ACS9_PIG	KCNJ16	ENSSSCP00000041693	ENSSSCP00000070452	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Potassium voltage-gated channel subfamily J member 16.	0.531
A0A287ACS9_PIG	KCNJ2	ENSSSCP00000041693	ENSSSCP00000058999	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Inward rectifier potassium channel 2; Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be bl [...]	0.531
A0A287ACS9_PIG	KCNJ3	ENSSSCP00000041693	ENSSSCP00000061886	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Potassium voltage-gated channel subfamily J member 3.	0.538
A0A287ACS9_PIG	KCNJ4	ENSSSCP00000041693	ENSSSCP00000000110	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Potassium voltage-gated channel subfamily J member 4.	0.531