STRINGSTRING
PARVB PARVB KRT5 KRT5 IQGAP1 IQGAP1 CDH24 CDH24 TYROBP TYROBP LOC100525346 LOC100525346 LAMA3 LAMA3 CDH2 CDH2 FYN FYN TESK1 TESK1 PTK2B PTK2B PRKCI PRKCI CADM2 CADM2 CD151 CD151 CTNND1 CTNND1 CTNNA1 CTNNA1 KIRREL3 KIRREL3 NPHS2 NPHS2 FLNC FLNC CDH10 CDH10 GRB2 GRB2 JUP JUP CDH9 CDH9 SIRPA SIRPA ILK ILK CDH4 CDH4 ACTN1 ACTN1 NCK1 NCK1 CDH18 CDH18 PARD6G PARD6G COL17A1 COL17A1 SKAP2 SKAP2 LOC100736623 LOC100736623 FYB1 FYB1 CDH11 CDH11 ITGA6 ITGA6 CTNNB1 CTNNB1 LIMS2 LIMS2 AFDN AFDN DST DST CADM3 CADM3 CDH17 CDH17 ACTB ACTB PARD6B PARD6B NPHS1 NPHS1 LOC102161654 LOC102161654 MEGF11 MEGF11 ACTG1 ACTG1 NCK2 NCK2 ARHGEF6 ARHGEF6 CDH15 CDH15 CDH12 CDH12 VASP VASP FLNA FLNA NECTIN3 NECTIN3 FBLIM1 FBLIM1 PLEC PLEC LIMS1 LIMS1 CDH6 CDH6 KRT14 KRT14 CDH1 CDH1 SFTPD SFTPD CDH8 CDH8 CDH7 CDH7 CDH13 CDH13 NECTIN2 NECTIN2 RSU1 RSU1 WASL WASL KIRREL2 KIRREL2 PARD3 PARD3 FERMT2 FERMT2 PXN PXN PARVA PARVA KIRREL1 KIRREL1 CD47 CD47 PARD6A PARD6A ITGB4 ITGB4 F11R F11R NECTIN4 NECTIN4 SDK1 SDK1 CADM1 CADM1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PARVBParvin beta. (364 aa)
KRT5Keratin 5; Belongs to the intermediate filament family. (602 aa)
IQGAP1IQ motif containing GTPase activating protein 1. (1709 aa)
CDH24Cadherin-24 isoform 2; Cadherins are calcium-dependent cell adhesion proteins. (781 aa)
TYROBPTYRO protein tyrosine kinase-binding protein; Adapter protein which non-covalently associates with activating receptors found on the surface of a variety of immune cells to mediate signaling and cell activation following ligand binding by the receptors (By similarity). TYROBP is tyrosine-phosphorylated in the ITAM domain following ligand binding by the associated receptors which leads to activation of additional tyrosine kinases and subsequent cell activation (By similarity). Also has an inhibitory role in some cells (By similarity). Non-covalently associates with activating receptors [...] (109 aa)
LOC100525346Uncharacterized protein. (459 aa)
LAMA3Laminin subunit alpha 3. (3345 aa)
CDH2Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (906 aa)
FYNTyrosine-protein kinase Fyn; Non-receptor tyrosine-protein kinase that plays a role in many biological processes including regulation of cell growth and survival, cell adhesion, integrin-mediated signaling, cytoskeletal remodeling, cell motility, immune response and axon guidance. Inactive FYN is phosphorylated on its C-terminal tail within the catalytic domain. Following activation by PKA, the protein subsequently associates with PTK2/FAK1, allowing PTK2/FAK1 phosphorylation, activation and targeting to focal adhesions. Involved in the regulation of cell adhesion and motility through [...] (537 aa)
TESK1Dual specificity testis-specific protein kinase 1 isoform X1. (629 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (636 aa)
CADM2Cell adhesion molecule 2. (438 aa)
CD151Tetraspanin. (264 aa)
CTNND1Catenin delta 1. (940 aa)
CTNNA1Catenin alpha 1. (1090 aa)
KIRREL3Kirre like nephrin family adhesion molecule 3. (794 aa)
NPHS2NPHS2 stomatin family member, podocin. (378 aa)
FLNCFilamin-C isoform X4. (2720 aa)
CDH10Cadherin-10 isoform X1; Cadherins are calcium-dependent cell adhesion proteins. (788 aa)
GRB2Growth factor receptor-bound protein 2 isoform 1. (217 aa)
JUPJunction plakoglobin; Common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE- cadherin function in endothelial cells. Can replace beta-catenin in E- cadherin/catenin adhes [...] (744 aa)
CDH9Cadherin-9 preproprotein; Cadherins are calcium-dependent cell adhesion proteins. (789 aa)
SIRPAUncharacterized protein. (533 aa)
ILKIntegrin linked kinase. (479 aa)
CDH4Cadherin 4; Cadherins are calcium-dependent cell adhesion proteins. (914 aa)
ACTN1Uncharacterized protein. (888 aa)
NCK1Cytoplasmic protein. (377 aa)
CDH18Cadherin 18; Cadherins are calcium-dependent cell adhesion proteins. (797 aa)
PARD6GPar-6 family cell polarity regulator gamma. (364 aa)
COL17A1Collagen type XVII alpha 1 chain. (1506 aa)
SKAP2Src kinase associated phosphoprotein 2. (423 aa)
LOC100736623Ig-like domain-containing protein. (181 aa)
FYB1FYN binding protein 1. (837 aa)
CDH11Cadherin-11 isoform X1; Cadherins are calcium-dependent cell adhesion proteins. (796 aa)
ITGA6Integrin subunit alpha 6; Belongs to the integrin alpha chain family. (1072 aa)
CTNNB1Catenin beta 1. (808 aa)
LIMS2LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. (357 aa)
AFDNAfadin, adherens junction formation factor. (1815 aa)
DSTDystonin. (7797 aa)
CADM3Cell adhesion molecule 3 isoform 1. (430 aa)
CDH17Cadherin-17. (832 aa)
ACTBActin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (375 aa)
PARD6BUncharacterized protein. (401 aa)
NPHS1NPHS1 adhesion molecule, nephrin. (1239 aa)
LOC102161654Uncharacterized protein. (390 aa)
MEGF11Multiple EGF like domains 11. (1140 aa)
ACTG1Actin gamma 1. (381 aa)
NCK2Cytoplasmic protein. (376 aa)
ARHGEF6Rac/Cdc42 guanine nucleotide exchange factor 6. (773 aa)
CDH15Cadherin-15 preproprotein; Cadherins are calcium-dependent cell adhesion proteins. (785 aa)
CDH12Cadherin-12 isoform X1; Cadherins are calcium-dependent cell adhesion proteins. (794 aa)
VASPVasodilator stimulated phosphoprotein. (389 aa)
FLNAFilamin A. (2897 aa)
NECTIN3Nectin cell adhesion molecule 3. (549 aa)
FBLIM1Filamin binding LIM protein 1. (415 aa)
PLECPlectin. (5422 aa)
LIMS1LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. (397 aa)
CDH6Cadherin 6; Cadherins are calcium-dependent cell adhesion proteins. (789 aa)
KRT14Keratin 14; Belongs to the intermediate filament family. (515 aa)
CDH1Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (925 aa)
SFTPDPulmonary surfactant-associated protein D; Contributes to the lung's defense against inhaled microorganisms, organic antigens and toxins. Interacts with compounds such as bacterial lipopolysaccharides, oligosaccharides and fatty acids and modulates leukocyte action in immune response. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha- glucosyl moieties (By similarity); Belongs to the SFTPD family. (386 aa)
CDH8Cadherin 8; Cadherins are calcium-dependent cell adhesion proteins. (799 aa)
CDH7Cadherin-7 isoform 1 preproprotein; Cadherins are calcium-dependent cell adhesion proteins. (785 aa)
CDH13Uncharacterized protein. (771 aa)
NECTIN2Uncharacterized protein. (616 aa)
RSU1Ras suppressor protein 1. (281 aa)
WASLWASP like actin nucleation promoting factor. (511 aa)
KIRREL2Kirre like nephrin family adhesion molecule 2. (711 aa)
PARD3Par-3 family cell polarity regulator. (1355 aa)
FERMT2Fermitin family member 2. (776 aa)
PXNUncharacterized protein. (1072 aa)
PARVAParvin alpha. (373 aa)
KIRREL1Kirre like nephrin family adhesion molecule 1. (773 aa)
CD47Leukocyte surface antigen CD47; Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. Plays an important role in memory formation and synaptic plasticity in the hippocampus. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeabili [...] (340 aa)
PARD6APar-6 family cell polarity regulator alpha. (354 aa)
ITGB4Integrin beta. (1814 aa)
F11RUncharacterized protein. (347 aa)
NECTIN4Nectin cell adhesion molecule 4. (525 aa)
SDK1Sidekick cell adhesion molecule 1. (2141 aa)
CADM1Cell adhesion molecule 1. (473 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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