32 items (Sus scrofa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	EMILIN3	Elastin microfibril interfacer 3. (766 aa)
	LOXL1	Lysyl oxidase like 1. (591 aa)
	FBLN5	Fibulin-5 isoform X2. (461 aa)
	EMILIN2	Elastin microfibril interfacer 2. (1078 aa)
	BMP4	Bone morphogenetic protein 4. (409 aa)
	BMP7	Bone morphogenetic protein 7. (650 aa)
	LOXL4	Lysyl oxidase like 4. (757 aa)
	ITGA8	Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1062 aa)
	VTN	Vitronectin; Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway (By similarity). (523 aa)
	GDF5	Growth differentiation factor 5. (499 aa)
	FBN3	Fibrillin 3. (2858 aa)
	TGFB1	Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] (390 aa)
	TGFB3	Transforming growth factor beta-3 proprotein; Transforming growth factor beta-3 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-3 (TGF-beta-3) chains, which constitute the regulatory and active subunit of TGF-beta-3, respectively. Transforming growth factor beta-3: Multifunctional protein that regulates embryogenesis and cell differentiation and is required in various processes such as secondary palate development (By similarity). Activation into mature form follows different steps: following cleavage of the proprotein in the Golgi appa [...] (456 aa)
	ITGAV	Integrin subunit alpha V; Belongs to the integrin alpha chain family. (1052 aa)
	LTBP1	Latent transforming growth factor beta binding protein 1. (1708 aa)
	BMP2	Bone morphogenetic protein 2 preproprotein. (395 aa)
	BMP10	Bone morphogenetic protein 10 preproprotein. (423 aa)
	LOXL2	Lysyl oxidase like 2. (758 aa)
	ITGB8	Integrin beta; Belongs to the integrin beta chain family. (722 aa)
	ELN	Elastin. (674 aa)
	ITGB5	Integrin beta; Belongs to the integrin beta chain family. (800 aa)
	MFAP4	Microfibril associated protein 4. (304 aa)
	FURIN	Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. (797 aa)
	EFEMP2	EGF containing fibulin extracellular matrix protein 2. (498 aa)
	LTBP3	Latent transforming growth factor beta binding protein 3. (1332 aa)
	EMILIN1	Elastin microfibril interfacer 1. (1292 aa)
	FBN2	Fibrillin 2. (2910 aa)
	MFAP2	Microfibril associated protein 2. (276 aa)
	LOXL3	Lysyl oxidase like 3. (814 aa)
	LTBP4	Latent transforming growth factor beta binding protein 4. (1622 aa)
	MFAP5	Microfibril associated protein 5. (236 aa)
	ITGB3	Integrin beta; Belongs to the integrin beta chain family. (835 aa)

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP10	BMP2	ENSSSCP00000039673	ENSSSCP00000037008	Bone morphogenetic protein 10 preproprotein.	Bone morphogenetic protein 2 preproprotein.	0.447
BMP10	BMP4	ENSSSCP00000039673	ENSSSCP00000005423	Bone morphogenetic protein 10 preproprotein.	Bone morphogenetic protein 4.	0.646
BMP10	BMP7	ENSSSCP00000039673	ENSSSCP00000007993	Bone morphogenetic protein 10 preproprotein.	Bone morphogenetic protein 7.	0.502
BMP10	GDF5	ENSSSCP00000039673	ENSSSCP00000023243	Bone morphogenetic protein 10 preproprotein.	Growth differentiation factor 5.	0.427
BMP2	BMP10	ENSSSCP00000037008	ENSSSCP00000039673	Bone morphogenetic protein 2 preproprotein.	Bone morphogenetic protein 10 preproprotein.	0.447
BMP2	BMP4	ENSSSCP00000037008	ENSSSCP00000005423	Bone morphogenetic protein 2 preproprotein.	Bone morphogenetic protein 4.	0.907
BMP2	BMP7	ENSSSCP00000037008	ENSSSCP00000007993	Bone morphogenetic protein 2 preproprotein.	Bone morphogenetic protein 7.	0.720
BMP2	GDF5	ENSSSCP00000037008	ENSSSCP00000023243	Bone morphogenetic protein 2 preproprotein.	Growth differentiation factor 5.	0.577
BMP2	TGFB1	ENSSSCP00000037008	ENSSSCP00000030317	Bone morphogenetic protein 2 preproprotein.	Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...]	0.508
BMP4	BMP10	ENSSSCP00000005423	ENSSSCP00000039673	Bone morphogenetic protein 4.	Bone morphogenetic protein 10 preproprotein.	0.646
BMP4	BMP2	ENSSSCP00000005423	ENSSSCP00000037008	Bone morphogenetic protein 4.	Bone morphogenetic protein 2 preproprotein.	0.907
BMP4	BMP7	ENSSSCP00000005423	ENSSSCP00000007993	Bone morphogenetic protein 4.	Bone morphogenetic protein 7.	0.842
BMP4	GDF5	ENSSSCP00000005423	ENSSSCP00000023243	Bone morphogenetic protein 4.	Growth differentiation factor 5.	0.565
BMP4	VTN	ENSSSCP00000005423	ENSSSCP00000020670	Bone morphogenetic protein 4.	Vitronectin; Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway (By similarity).	0.458
BMP7	BMP10	ENSSSCP00000007993	ENSSSCP00000039673	Bone morphogenetic protein 7.	Bone morphogenetic protein 10 preproprotein.	0.502
BMP7	BMP2	ENSSSCP00000007993	ENSSSCP00000037008	Bone morphogenetic protein 7.	Bone morphogenetic protein 2 preproprotein.	0.720
BMP7	BMP4	ENSSSCP00000007993	ENSSSCP00000005423	Bone morphogenetic protein 7.	Bone morphogenetic protein 4.	0.842
BMP7	FBN2	ENSSSCP00000007993	ENSSSCP00000065623	Bone morphogenetic protein 7.	Fibrillin 2.	0.415
BMP7	GDF5	ENSSSCP00000007993	ENSSSCP00000023243	Bone morphogenetic protein 7.	Growth differentiation factor 5.	0.592
BMP7	TGFB1	ENSSSCP00000007993	ENSSSCP00000030317	Bone morphogenetic protein 7.	Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...]	0.696