(34 nodes) Transport of the SLBP independent Mature mRNA network (Sus scrofa)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NPAP1	Uncharacterized protein. (1181 aa)
	NUP54	Nucleoporin 54. (564 aa)
	NUP210	Nucleoporin 210. (1946 aa)
	NUP160	Nucleoporin 160. (1437 aa)
	NUP98	Nucleoporin 98. (1753 aa)
	F1SRM6_PIG	Uncharacterized protein. (954 aa)
	NUP85	Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (684 aa)
	NUP205	Nucleoporin 205. (2026 aa)
	NCBP2	Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (156 aa)
	RANBP2	RAN binding protein 2. (3233 aa)
	EIF4E	Eukaryotic translation initiation factor 4E; Belongs to the eukaryotic initiation factor 4E family. (237 aa)
	RAE1	mRNA export factor; Plays a role in mitotic bipolar spindle formation. Binds mRNA. May function in nucleocytoplasmic transport and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. (368 aa)
	TPR	Translocated promoter region, nuclear basket protein. (2518 aa)
	NUP88	Nucleoporin 88. (739 aa)
	NUP214	Nucleoporin 214. (2016 aa)
	NUP155	Nucleoporin 155. (1391 aa)
	NUP93	Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance; Belongs to the nucleoporin interacting component (NIC) family. (797 aa)
	POM121C	Uncharacterized protein. (1193 aa)
	NUP133	Nucleoporin 133. (1160 aa)
	NUP62	Nucleoporin 62. (478 aa)
	NUP37	Nucleoporin Nup37. (333 aa)
	NUP43	Nucleoporin Nup43 isoform X2. (380 aa)
	NUP188	Nucleoporin 188. (1769 aa)
	NXF1	Nuclear RNA export factor 1. (721 aa)
	NUP107	Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (925 aa)
	NUP42	Nucleoporin-like protein 2. (418 aa)
	NUP153	Nucleoporin 153. (1473 aa)
	AAAS	Aladin WD repeat nucleoporin. (554 aa)
	NUP35	Nucleoporin NUP53; Functions as a component of the nuclear pore complex (NPC). Belongs to the Nup35 family. (327 aa)
	NCBP1	Nuclear cap binding protein subunit 1. (1117 aa)
	NDC1	NDC1 transmembrane nucleoporin. (757 aa)
	ALYREF	Aly/REF export factor. (348 aa)
	SEC13	SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family. (341 aa)
	NUP58	Nucleoporin 58. (583 aa)

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AAAS	ALYREF	ENSSSCP00000064695	ENSSSCP00000071154	Aladin WD repeat nucleoporin.	Aly/REF export factor.	0.526
AAAS	EIF4E	ENSSSCP00000064695	ENSSSCP00000027266	Aladin WD repeat nucleoporin.	Eukaryotic translation initiation factor 4E; Belongs to the eukaryotic initiation factor 4E family.	0.400
AAAS	F1SRM6_PIG	ENSSSCP00000064695	ENSSSCP00000017784	Aladin WD repeat nucleoporin.	Uncharacterized protein.	0.674
AAAS	NCBP1	ENSSSCP00000064695	ENSSSCP00000064837	Aladin WD repeat nucleoporin.	Nuclear cap binding protein subunit 1.	0.499
AAAS	NCBP2	ENSSSCP00000064695	ENSSSCP00000024947	Aladin WD repeat nucleoporin.	Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...]	0.499
AAAS	NDC1	ENSSSCP00000064695	ENSSSCP00000065756	Aladin WD repeat nucleoporin.	NDC1 transmembrane nucleoporin.	0.982
AAAS	NPAP1	ENSSSCP00000064695	ENSSSCP00000065967	Aladin WD repeat nucleoporin.	Uncharacterized protein.	0.499
AAAS	NUP107	ENSSSCP00000064695	ENSSSCP00000062756	Aladin WD repeat nucleoporin.	Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC).	0.932
AAAS	NUP133	ENSSSCP00000064695	ENSSSCP00000042477	Aladin WD repeat nucleoporin.	Nucleoporin 133.	0.870
AAAS	NUP153	ENSSSCP00000064695	ENSSSCP00000063833	Aladin WD repeat nucleoporin.	Nucleoporin 153.	0.880
AAAS	NUP155	ENSSSCP00000064695	ENSSSCP00000039770	Aladin WD repeat nucleoporin.	Nucleoporin 155.	0.925
AAAS	NUP160	ENSSSCP00000064695	ENSSSCP00000014051	Aladin WD repeat nucleoporin.	Nucleoporin 160.	0.866
AAAS	NUP188	ENSSSCP00000064695	ENSSSCP00000058490	Aladin WD repeat nucleoporin.	Nucleoporin 188.	0.957
AAAS	NUP205	ENSSSCP00000064695	ENSSSCP00000021604	Aladin WD repeat nucleoporin.	Nucleoporin 205.	0.910
AAAS	NUP210	ENSSSCP00000064695	ENSSSCP00000012374	Aladin WD repeat nucleoporin.	Nucleoporin 210.	0.883
AAAS	NUP214	ENSSSCP00000064695	ENSSSCP00000034207	Aladin WD repeat nucleoporin.	Nucleoporin 214.	0.953
AAAS	NUP35	ENSSSCP00000064695	ENSSSCP00000064731	Aladin WD repeat nucleoporin.	Nucleoporin NUP53; Functions as a component of the nuclear pore complex (NPC). Belongs to the Nup35 family.	0.865
AAAS	NUP37	ENSSSCP00000064695	ENSSSCP00000056920	Aladin WD repeat nucleoporin.	Nucleoporin Nup37.	0.885
AAAS	NUP42	ENSSSCP00000064695	ENSSSCP00000063720	Aladin WD repeat nucleoporin.	Nucleoporin-like protein 2.	0.907
AAAS	NUP43	ENSSSCP00000064695	ENSSSCP00000057685	Aladin WD repeat nucleoporin.	Nucleoporin Nup43 isoform X2.	0.831