STRINGSTRING
RALGDS RALGDS RAPGEF1 RAPGEF1 NTRK1 NTRK1 SOS1 SOS1 CRKL CRKL MAPKAPK2 MAPKAPK2 GRB2 GRB2 KRAS KRAS SHC1 SHC1 MAP2K2 MAP2K2 MAPK11 MAPK11 CRK CRK BRAF BRAF MAPKAPK3 MAPKAPK3 NRAS NRAS RAP1A RAP1A HRAS HRAS FRS2 FRS2 SHC3 SHC3 KIDINS220 KIDINS220 MAPK3 MAPK3 YWHAB YWHAB SHC2 SHC2 MAPK14 MAPK14 MAPK1 MAPK1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RALGDSUncharacterized protein. (938 aa)
RAPGEF1Rap guanine nucleotide exchange factor 1. (1093 aa)
NTRK1Tyrosine-protein kinase receptor. (795 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1369 aa)
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)
MAPKAPK2MAPK activated protein kinase 2; Belongs to the protein kinase superfamily. (361 aa)
GRB2Growth factor receptor-bound protein 2 isoform 1. (217 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
SHC1SHC adaptor protein 1. (583 aa)
MAP2K2Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
MAPK11Mitogen-activated protein kinase. (364 aa)
CRKCRK proto-oncogene, adaptor protein. (385 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (804 aa)
MAPKAPK3Mitogen-activated protein kinase-activated protein kinase 3; Belongs to the protein kinase superfamily. (384 aa)
NRASGTPase NRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. (189 aa)
RAP1ARAP1A, member of RAS oncogene family. (184 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
FRS2Fibroblast growth factor receptor substrate 2. (550 aa)
SHC3SHC adaptor protein 3. (656 aa)
KIDINS220Kinase D interacting substrate 220. (1782 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (361 aa)
YWHABTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (264 aa)
SHC2Uncharacterized protein. (623 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (568 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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