STRINGSTRING
PIK3R4 PIK3R4 KIF5A KIF5A LOC100152135 LOC100152135 LOC100152878 LOC100152878 KLC4 KLC4 SRF SRF IQGAP1 IQGAP1 KLC1 KLC1 B9D2 B9D2 DVL1 DVL1 CENPS CENPS KDM1A KDM1A KIF2C KIF2C CDC20 CDC20 NOX3 NOX3 SKA1 SKA1 DAAM1 DAAM1 PKN3 PKN3 YWHAZ YWHAZ NUF2 NUF2 IQGAP3 IQGAP3 H2AC20 H2AC20 LOC102159655 LOC102159655 RHOC RHOC RHPN1 RHPN1 TUBB1 TUBB1 ARPC1A ARPC1A NCF1 NCF1 NOXO1 NOXO1 CENPP CENPP CENPC CENPC H2AFZ H2AFZ WASF3 WASF3 DIAPH3 DIAPH3 CLIP1 CLIP1 ARPC3 ARPC3 DYNLL1 DYNLL1 LOC100155267 LOC100155267 NF2 NF2 YWHAH YWHAH BUB3 BUB3 KIF5B KIF5B ABI1 ABI1 LOC100127131 LOC100127131 SGO1 SGO1 NCKIPSD NCKIPSD BRK1 BRK1 PAK2 PAK2 PPP2R5B PPP2R5B MEN1 MEN1 INCENP INCENP NUP160 NUP160 KIF18A KIF18A PPP2CA PPP2CA CDC25C CDC25C CTNNA1 CTNNA1 NUP98 NUP98 ZW10 ZW10 CENPL CENPL ARPC5 ARPC5 CENPF CENPF NSL1 NSL1 PPP2R5A PPP2R5A ACTR3 ACTR3 SGO2 SGO2 CENPK CENPK LOC100521680 LOC100521680 GRB2 GRB2 NUP85 NUP85 PRKCA PRKCA KIF2B KIF2B SKA2 SKA2 TAOK1 TAOK1 TAX1BP3 TAX1BP3 PFN1 PFN1 PFN2 PFN2 DVL2 DVL2 ZWINT ZWINT I3LAJ9_PIG I3LAJ9_PIG LOC100510930 LOC100510930 BUB1B BUB1B HIST1H2BD HIST1H2BD ERCC6L ERCC6L WASF2 WASF2 KIF2A KIF2A MYH14 MYH14 PLK1 PLK1 LOC100158121 LOC100158121 RHOD RHOD PIN1 PIN1 RANBP2 RANBP2 DVL3 DVL3 NCK1 NCK1 CENPH CENPH RHPN2 RHPN2 SPDL1 SPDL1 PRKCZ PRKCZ LOC100621389 LOC100621389 IQGAP2 IQGAP2 S100A9 S100A9 CDC42 CDC42 SRC SRC S100A8 S100A8 NOX1 NOX1 PAK1 PAK1 MAD2L1 MAD2L1 CTNNB1 CTNNB1 MAPK11 MAPK11 PKN2 PKN2 NDE1 NDE1 MAPRE1 MAPRE1 ARPC1B ARPC1B A0A286ZRB3_PIG A0A286ZRB3_PIG SPC25 SPC25 XPO1 XPO1 DYNC1I2 DYNC1I2 CLASP1 CLASP1 ACTB ACTB PDPK1 PDPK1 NCF2 NCF2 MRTFA MRTFA ARPC4 ARPC4 ACTR2 ACTR2 KTN1 KTN1 AHCTF1 AHCTF1 ARPC2 ARPC2 CENPA CENPA CDCA8 CDCA8 ABI2 ABI2 TUBB4B TUBB4B PPP1R14A PPP1R14A MAD1L1 MAD1L1 RHOQ RHOQ GOPC GOPC H2BC11 H2BC11 CLASP2 CLASP2 ACTG1 ACTG1 KDM4C KDM4C PMF1 PMF1 BIRC5 BIRC5 NCOA2 NCOA2 NUP133 NUP133 WIPF1 WIPF1 MIS12 MIS12 DYNC1LI1 DYNC1LI1 NCKAP1 NCKAP1 CKAP5 CKAP5 KNTC1 KNTC1 RCC2 RCC2 H2AJ H2AJ RHOA RHOA WASF1 WASF1 CENPM CENPM CYFIP2 CYFIP2 CENPQ CENPQ FMNL1 FMNL1 FLNA FLNA H2BU1 H2BU1 PKN1 PKN1 DYNC1I1 DYNC1I1 NOXA1 NOXA1 PPP1CB PPP1CB PPP2R5E PPP2R5E RHOG RHOG TUBA8 TUBA8 SPC24 SPC24 CENPT CENPT TUBB6 TUBB6 TUBA1A TUBA1A CENPE CENPE PPP1R12B PPP1R12B NDEL1 NDEL1 NUDC NUDC LIN7B LIN7B H2AC6 H2AC6 HIST1H3E HIST1H3E ABL1 ABL1 PRKCD PRKCD LOC100620620 LOC100620620 RTKN RTKN PPP2R5D PPP2R5D CENPN CENPN H2BC21 H2BC21 MYL9 MYL9 DLG4 DLG4 PPP2CB PPP2CB CIT CIT SEC13 SEC13 FMNL2 FMNL2 NCF4 NCF4 LIMK1 LIMK1 MAPK1 MAPK1 TUBAL3 TUBAL3 KLC2 KLC2 BAIAP2 BAIAP2 NUP37 NUP37 MAPK3 MAPK3 NUP43 NUP43 CDH1 CDH1 YWHAB YWHAB RPS27 RPS27 ZWILCH ZWILCH YWHAG YWHAG SRGAP2 SRGAP2 DYNC1LI2 DYNC1LI2 H2AX H2AX ROCK2 ROCK2 PPP1CC PPP1CC MYL6 MYL6 WASL WASL RAC1 RAC1 DIAPH2 DIAPH2 NUP107 NUP107 ROCK1 ROCK1 CENPI CENPI MAPK14 MAPK14 YWHAQ YWHAQ SCAI SCAI NCKAP1L NCKAP1L PPP1R12A PPP1R12A CENPU CENPU NDC80 NDC80 PPP2R5C PPP2R5C KLC3 KLC3 RHOB RHOB RANGAP1 RANGAP1 RAC2 RAC2 DYNLL2 DYNLL2 DSN1 DSN1 H2AZ2 H2AZ2 TUBA4A TUBA4A A0A5G2R693_PIG A0A5G2R693_PIG BUB1 BUB1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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co-expression
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PIK3R4Phosphoinositide-3-kinase regulatory subunit 4. (1302 aa)
KIF5AKinesin family member 5A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1085 aa)
LOC100152135Histone H2B; Belongs to the histone H2B family. (127 aa)
LOC100152878Histone H2B; Belongs to the histone H2B family. (127 aa)
KLC4Kinesin light chain 4 isoform X1. (616 aa)
SRFSerum response factor. (512 aa)
IQGAP1IQ motif containing GTPase activating protein 1. (1709 aa)
KLC1Uncharacterized protein. (677 aa)
B9D2B9 domain-containing protein 2 isoform X1. (175 aa)
DVL1Dishevelled segment polarity protein 1. (700 aa)
CENPSCentromere protein S. (139 aa)
KDM1ALysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (875 aa)
KIF2CKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (725 aa)
CDC20Cell division cycle protein 20 homolog; Required for full ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) and may confer substrate specificity upon the complex. Is regulated by MAD2L1: in metaphase the MAD2L1-CDC20-APC/C ternary complex is inactive and in anaphase the CDC20-APC/C binary complex is active in degrading substrates. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 induces presynaptic differentia [...] (499 aa)
NOX3NADPH oxidase 3. (568 aa)
SKA1Spindle and kinetochore associated complex subunit 1. (255 aa)
DAAM1Dishevelled associated activator of morphogenesis 1. (1086 aa)
PKN3Protein kinase N3. (861 aa)
YWHAZTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; Belongs to the 14-3-3 family. (260 aa)
NUF2NUF2 component of NDC80 kinetochore complex. (464 aa)
IQGAP3IQ motif containing GTPase activating protein 3. (1696 aa)
H2AC20Histone H2A; Belongs to the histone H2A family. (129 aa)
LOC102159655Histone H2A; Belongs to the histone H2A family. (130 aa)
RHOCRas homolog family member C. (202 aa)
RHPN1Rhophilin Rho GTPase binding protein 1. (659 aa)
TUBB1Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
ARPC1AActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (370 aa)
NCF1Uncharacterized protein. (378 aa)
NOXO1NADPH oxidase organizer 1. (400 aa)
CENPPCentromere protein P. (286 aa)
CENPCCentromere protein C. (951 aa)
H2AFZHistone H2A; Belongs to the histone H2A family. (128 aa)
WASF3Wiskott-Aldrich syndrome protein family member 3 isoform X1. (498 aa)
DIAPH3Diaphanous related formin 3. (1138 aa)
CLIP1CAP-Gly domain containing linker protein 1. (2193 aa)
ARPC3Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (178 aa)
DYNLL1Dynein light chain. (89 aa)
LOC100155267Histone domain-containing protein; Belongs to the histone H2B family. (126 aa)
NF2Neurofibromin 2. (586 aa)
YWHAHTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta; Belongs to the 14-3-3 family. (246 aa)
BUB3BUB3 mitotic checkpoint protein. (328 aa)
KIF5BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (963 aa)
ABI1Abl interactor 1 isoform b. (481 aa)
LOC100127131Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (474 aa)
SGO1Shugoshin 1. (529 aa)
NCKIPSDNCK interacting protein with SH3 domain. (715 aa)
BRK1BRICK1 subunit of SCAR/WAVE actin nucleating complex. (103 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
PPP2R5BSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (497 aa)
MEN1Menin 1. (704 aa)
INCENPInner centromere protein. (848 aa)
NUP160Nucleoporin 160. (1437 aa)
KIF18AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (904 aa)
PPP2CASerine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGO2 to protect centromeric cohesin from separase- mediated cleavage in oocytes specifically during meiosis I. Activates RAF1 by dephosphorylating it at 'Ser-259' (By similarity). (309 aa)
CDC25CM-phase inducer phosphatase 3; Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle. Directly dephosphorylates CDK1 and activates its kinase activity. When phosphorylated, highly effective in activating G2 cells into prophase (By similarity). (501 aa)
CTNNA1Catenin alpha 1. (1090 aa)
NUP98Nucleoporin 98. (1753 aa)
ZW10Centromere/kinetochore protein zw10 homolog. (779 aa)
CENPLCentromere protein L. (370 aa)
ARPC5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (151 aa)
CENPFCentromere protein F. (3035 aa)
NSL1NSL1 component of MIS12 kinetochore complex. (290 aa)
PPP2R5ASerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (487 aa)
ACTR3Actin related protein 3; Belongs to the actin family. (422 aa)
SGO2Shugoshin 2 isoform X1. (1369 aa)
CENPKCentromere protein K. (289 aa)
LOC100521680Histone H3.3; Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in [...] (136 aa)
GRB2Growth factor receptor-bound protein 2 isoform 1. (217 aa)
NUP85Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (684 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (669 aa)
KIF2BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (684 aa)
SKA2Spindle and kinetochore-associated protein 2 isoform 1. (121 aa)
TAOK1Serine/threonine-protein kinase TAO1 isoform 1. (1001 aa)
TAX1BP3Tax1 binding protein 3. (191 aa)
PFN1Profilin; Belongs to the profilin family. (212 aa)
PFN2Profilin; Belongs to the profilin family. (189 aa)
DVL2Dishevelled segment polarity protein 2. (794 aa)
ZWINTZW10 interacting kinetochore protein. (294 aa)
I3LAJ9_PIGHistone H2B; Belongs to the histone H2B family. (168 aa)
LOC100510930Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (469 aa)
BUB1BBUB1 N-terminal domain-containing protein. (1092 aa)
HIST1H2BDHistone H2B; Belongs to the histone H2B family. (126 aa)
ERCC6LERCC excision repair 6 like, spindle assembly checkpoint helicase. (1247 aa)
WASF2Wiskott-Aldrich syndrome protein family member 2 isoform 2. (498 aa)
KIF2AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (744 aa)
MYH14Myosin heavy chain 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2040 aa)
PLK1Serine/threonine-protein kinase PLK. (601 aa)
LOC100158121Histone H2A; Belongs to the histone H2A family. (130 aa)
RHODRas homolog family member D. (203 aa)
PIN1Peptidyl-prolyl cis-trans isomerase. (163 aa)
RANBP2RAN binding protein 2. (3233 aa)
DVL3Segment polarity protein dishevelled homolog DVL-3 isoform X1. (716 aa)
NCK1Cytoplasmic protein. (377 aa)
CENPHCentromere protein H. (245 aa)
RHPN2Rhophilin Rho GTPase binding protein 2. (686 aa)
SPDL1Protein Spindly; Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment. (605 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (629 aa)
LOC100621389Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
IQGAP2IQ motif containing GTPase activating protein 2. (1542 aa)
S100A9EF-hand domain-containing protein; Belongs to the S-100 family. (222 aa)
CDC42Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] (197 aa)
SRCTyrosine-protein kinase. (559 aa)
S100A8Protein S100; Belongs to the S-100 family. (89 aa)
NOX1NADPH oxidase 1 isoform 1. (564 aa)
PAK1Non-specific serine/threonine protein kinase. (546 aa)
MAD2L1Mitotic arrest deficient 2 like 1. (205 aa)
CTNNB1Catenin beta 1. (808 aa)
MAPK11Mitogen-activated protein kinase. (364 aa)
PKN2Serine/threonine-protein kinase N2 isoform 1. (983 aa)
NDE1NudE neurodevelopment protein 1. (346 aa)
MAPRE1Microtubule associated protein RP/EB family member 1. (333 aa)
ARPC1BActin related protein 2/3 complex subunit 1B. (440 aa)
A0A286ZRB3_PIGHistone domain-containing protein. (130 aa)
SPC25SPC25 component of NDC80 kinetochore complex. (243 aa)
XPO1Exportin 1. (1071 aa)
DYNC1I2WD_REPEATS_REGION domain-containing protein. (581 aa)
CLASP1Cytoplasmic linker associated protein 1. (1540 aa)
ACTBActin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (375 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (668 aa)
NCF2Neutrophil cytosolic factor 2. (643 aa)
MRTFAMyocardin related transcription factor A. (1239 aa)
ARPC4Actin related protein 2/3 complex subunit 4. (231 aa)
ACTR2Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (404 aa)
KTN1Kinectin 1. (1358 aa)
AHCTF1AT-hook containing transcription factor 1. (2333 aa)
ARPC2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (273 aa)
CENPACentromere protein A. (131 aa)
CDCA8Cell division cycle associated 8. (308 aa)
ABI2Abl interactor 2. (542 aa)
TUBB4BTubulin beta 4B class IVb; Belongs to the tubulin family. (561 aa)
PPP1R14AProtein phosphatase 1 regulatory subunit 14A; Inhibitor of PPP1CA. Has over 1000-fold higher inhibitory activity when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction. (147 aa)
MAD1L1Mitotic arrest deficient 1 like 1. (737 aa)
RHOQRho-related GTP-binding protein RhoQ. (205 aa)
GOPCPDZ domain-containing protein. (463 aa)
H2BC11Histone H2B; Belongs to the histone H2B family. (149 aa)
CLASP2Uncharacterized protein. (1530 aa)
ACTG1Actin gamma 1. (381 aa)
KDM4CLysine demethylase 4C. (1056 aa)
PMF1Uncharacterized protein. (204 aa)
BIRC5Baculoviral IAP repeat-containing protein 5; Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (By similarity). Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis (By similarity). Acts as an important regulator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with p [...] (142 aa)
NCOA2Nuclear receptor coactivator. (1463 aa)
NUP133Nucleoporin 133. (1160 aa)
WIPF1WH2 domain-containing protein. (515 aa)
MIS12MIS12 kinetochore complex component. (206 aa)
DYNC1LI1Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (524 aa)
NCKAP1NCK associated protein 1. (1134 aa)
CKAP5Cytoskeleton associated protein 5. (2076 aa)
KNTC1Kinetochore associated 1. (2207 aa)
RCC2Regulator of chromosome condensation 2. (554 aa)
H2AJHistone H2A; Belongs to the histone H2A family. (129 aa)
RHOATransforming protein RhoA isoform 1. (193 aa)
WASF1WH2 domain-containing protein. (559 aa)
CENPMCentromere protein M. (162 aa)
CYFIP2Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1278 aa)
CENPQCentromere protein Q. (269 aa)
FMNL1Formin like 1. (1175 aa)
FLNAFilamin A. (2897 aa)
H2BU1Histone H2B; Belongs to the histone H2B family. (126 aa)
PKN1Protein kinase N1. (956 aa)
DYNC1I1Cytoplasmic dynein 1 intermediate chain 1 isoform X1. (645 aa)
NOXA1NADPH oxidase activator 1. (474 aa)
PPP1CBSerine/threonine-protein phosphatase PP1-beta catalytic subunit; Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase (PP1) is essential for cell division, it participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progressi [...] (389 aa)
PPP2R5ESerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (477 aa)
RHOGUncharacterized protein. (394 aa)
TUBA8Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (497 aa)
SPC24SPC24 component of NDC80 kinetochore complex. (223 aa)
CENPTCentromere protein T. (565 aa)
TUBB6Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (411 aa)
TUBA1ADetyrosinated tubulin alpha-1B chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
CENPECentromere protein E; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (2733 aa)
PPP1R12BProtein phosphatase 1 regulatory subunit. (1012 aa)
NDEL1NudE neurodevelopment protein 1 like 1. (394 aa)
NUDCCS domain-containing protein. (409 aa)
LIN7BProtein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (206 aa)
H2AC6Histone H2A; Belongs to the histone H2A family. (145 aa)
HIST1H3EHistone H3; Belongs to the histone H3 family. (136 aa)
ABL1Tyrosine-protein kinase. (1146 aa)
PRKCDProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (723 aa)
LOC100620620Histone H2A; Belongs to the histone H2A family. (113 aa)
RTKNRhotekin. (564 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (614 aa)
CENPNCentromere protein N. (339 aa)
H2BC21Histone H2B; Belongs to the histone H2B family. (126 aa)
MYL9Myosin regulatory light polypeptide 9; Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion. (176 aa)
DLG4Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. (764 aa)
PPP2CBSerine/threonine-protein phosphatase. (476 aa)
CITCitron Rho-interacting kinase; Plays a role in cytokinesis. Displays serine/threonine protein kinase activity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (2104 aa)
SEC13SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family. (341 aa)
FMNL2Formin like 2. (1092 aa)
NCF4Neutrophil cytosolic factor 4. (381 aa)
LIMK1LIM domain kinase 1. (681 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (568 aa)
TUBAL3Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa)
KLC2Ras-related protein Rab-1B. (865 aa)
BAIAP2BAI1 associated protein 2. (575 aa)
NUP37Nucleoporin Nup37. (333 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (361 aa)
NUP43Nucleoporin Nup43 isoform X2. (380 aa)
CDH1Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (925 aa)
YWHABTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (264 aa)
RPS2740S ribosomal protein S27. (84 aa)
ZWILCHZwilch kinetochore protein. (589 aa)
YWHAGTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma; Belongs to the 14-3-3 family. (247 aa)
SRGAP2Uncharacterized protein. (1087 aa)
DYNC1LI2Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (492 aa)
H2AXHistone H2A; Belongs to the histone H2A family. (143 aa)
ROCK2Rho-associated protein kinase 2; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of ADD1, BRCA2, CNN1, EZR, DPYSL2, EP300, MSN, MYL9/MLC2, NPM1, RDX, PPP1R12A and VIM. Phosphorylates SORL1 and IRF4. Acts as a negative regulator of VEGF-induced angiogenic endothelial cell activation. Positively regulates the activation of p42/MAPK1- p44/MAPK3 and of p90RSK/RPS6K [...] (1397 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (369 aa)
MYL6Myosin light polypeptide 6; Regulatory light chain of myosin. Does not bind calcium. (278 aa)
WASLWASP like actin nucleation promoting factor. (511 aa)
RAC1Rac family small GTPase 1. (186 aa)
DIAPH2Diaphanous related formin 2. (1100 aa)
NUP107Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (925 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa)
CENPICentromere protein I. (747 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
YWHAQTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta; Belongs to the 14-3-3 family. (246 aa)
SCAIProtein SCAI; Tumor suppressor which functions to suppress MRTFA-induced SRF transcriptional activity. (606 aa)
NCKAP1LNCK associated protein 1 like. (1128 aa)
PPP1R12AProtein phosphatase 1 regulatory subunit. (1028 aa)
CENPUCentromere protein U. (454 aa)
NDC80NDC80 kinetochore complex component. (677 aa)
PPP2R5CSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (659 aa)
KLC3Kinesin light chain 3. (549 aa)
RHOBRho-related GTP-binding protein RhoB. (196 aa)
RANGAP1Ran GTPase activating protein 1. (585 aa)
RAC2Rac family small GTPase 2. (217 aa)
DYNLL2Dynein light chain. (133 aa)
DSN1Kinetochore-associated protein DSN1 homolog isoform 1. (356 aa)
H2AZ2Histone H2A; Belongs to the histone H2A family. (145 aa)
TUBA4ATubulin alpha 4a; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (618 aa)
A0A5G2R693_PIGTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (517 aa)
BUB1BUB1 mitotic checkpoint serine/threonine kinase. (1085 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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