STRINGSTRING
A0A286ZRB3_PIG A0A286ZRB3_PIG LOC100152135 LOC100152135 LOC100152878 LOC100152878 TLE3 TLE3 H2AC20 H2AC20 LOC102159655 LOC102159655 CREBBP CREBBP F1RWC9_PIG F1RWC9_PIG H2AFZ H2AFZ LOC100155267 LOC100155267 TCF7L2 TCF7L2 CDC73 CDC73 MEN1 MEN1 RBBP5 RBBP5 TERT TERT LOC100521680 LOC100521680 RUVBL1 RUVBL1 ASH2L ASH2L EP300 EP300 I3LAJ9_PIG I3LAJ9_PIG HDAC1 HDAC1 HIST1H2BD HIST1H2BD LOC100158121 LOC100158121 TCF7 TCF7 LOC100621389 LOC100621389 SMARCA4 SMARCA4 CTNNB1 CTNNB1 TLE4 TLE4 LEF1 LEF1 H2BC11 H2BC11 TRRAP TRRAP LEO1 LEO1 TLE1 TLE1 H2AJ H2AJ H2BU1 H2BU1 H2AC6 H2AC6 HIST1H3E HIST1H3E LOC100620620 LOC100620620 H2BC21 H2BC21 BCL9L BCL9L H2AX H2AX TCF7L1 TCF7L1 KAT5 KAT5 H2AZ2 H2AZ2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
A0A286ZRB3_PIGHistone domain-containing protein. (130 aa)
LOC100152135Histone H2B; Belongs to the histone H2B family. (127 aa)
LOC100152878Histone H2B; Belongs to the histone H2B family. (127 aa)
TLE3TLE family member 3, transcriptional corepressor. (808 aa)
H2AC20Histone H2A; Belongs to the histone H2A family. (129 aa)
LOC102159655Histone H2A; Belongs to the histone H2A family. (130 aa)
CREBBPCREB-binding protein isoform a. (2440 aa)
F1RWC9_PIGHistone domain-containing protein. (142 aa)
H2AFZHistone H2A; Belongs to the histone H2A family. (128 aa)
LOC100155267Histone domain-containing protein; Belongs to the histone H2B family. (126 aa)
TCF7L2Transcription factor 7 like 2. (669 aa)
CDC73Cell division cycle 73. (531 aa)
MEN1Menin 1. (704 aa)
RBBP5RB binding protein 5, histone lysine methyltransferase complex subunit. (517 aa)
TERTTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1130 aa)
LOC100521680Histone H3.3; Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in [...] (136 aa)
RUVBL1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (463 aa)
ASH2LASH2 like, histone lysine methyltransferase complex subunit. (635 aa)
EP300E1A binding protein p300. (2420 aa)
I3LAJ9_PIGHistone H2B; Belongs to the histone H2B family. (168 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (491 aa)
HIST1H2BDHistone H2B; Belongs to the histone H2B family. (126 aa)
LOC100158121Histone H2A; Belongs to the histone H2A family. (130 aa)
TCF7Transcription factor 7. (484 aa)
LOC100621389Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. (1647 aa)
CTNNB1Catenin beta 1. (808 aa)
TLE4TLE family member 4, transcriptional corepressor. (774 aa)
LEF1Lymphoid enhancer binding factor 1. (429 aa)
H2BC11Histone H2B; Belongs to the histone H2B family. (149 aa)
TRRAPTransformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family. (3858 aa)
LEO1LEO1 homolog, Paf1/RNA polymerase II complex component. (668 aa)
TLE1TLE family member 1, transcriptional corepressor. (770 aa)
H2AJHistone H2A; Belongs to the histone H2A family. (129 aa)
H2BU1Histone H2B; Belongs to the histone H2B family. (126 aa)
H2AC6Histone H2A; Belongs to the histone H2A family. (145 aa)
HIST1H3EHistone H3; Belongs to the histone H3 family. (136 aa)
LOC100620620Histone H2A; Belongs to the histone H2A family. (113 aa)
H2BC21Histone H2B; Belongs to the histone H2B family. (126 aa)
BCL9LBCL9 like. (1526 aa)
H2AXHistone H2A; Belongs to the histone H2A family. (143 aa)
TCF7L1HMG box domain-containing protein. (412 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (576 aa)
H2AZ2Histone H2A; Belongs to the histone H2A family. (145 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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