STRINGSTRING
CD3D CD3D A0A286ZKB7_PIG A0A286ZKB7_PIG PTPRC PTPRC A0A287AAB9_PIG A0A287AAB9_PIG A0A287AC24_PIG A0A287AC24_PIG CD3G CD3G LCK LCK A0A287ARF7_PIG A0A287ARF7_PIG SLA-DQA1 SLA-DQA1 A0A287AT33_PIG A0A287AT33_PIG A0A287BQ31_PIG A0A287BQ31_PIG PAG1 PAG1 LOC102158035 LOC102158035 A0A287BPL5_PIG A0A287BPL5_PIG SLA-DRB1 SLA-DRB1 A0A287BQ00_PIG A0A287BQ00_PIG HLA-DRA HLA-DRA CSK CSK PTPN22 PTPN22 CD4 CD4 I3LAQ5_PIG I3LAQ5_PIG PTPRJ PTPRJ
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CD3DT-cell surface glycoprotein CD3 delta chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of [...] (171 aa)
A0A286ZKB7_PIGIg-like domain-containing protein. (259 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1092 aa)
A0A287AAB9_PIGIg-like domain-containing protein. (252 aa)
A0A287AC24_PIGIg-like domain-containing protein. (112 aa)
CD3GT-cell surface glycoprotein CD3 gamma chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of [...] (176 aa)
LCKTyrosine-protein kinase. (520 aa)
A0A287ARF7_PIGIg-like domain-containing protein. (139 aa)
SLA-DQA1SLA class II histocompatibility antigen, DQ haplotype D alpha chain. (255 aa)
A0A287AT33_PIGIg-like domain-containing protein. (173 aa)
A0A287BQ31_PIGIg-like domain-containing protein. (180 aa)
PAG1Phosphoprotein membrane anchor with glycosphingolipid microdomains 1. (435 aa)
LOC102158035Ig-like domain-containing protein. (268 aa)
A0A287BPL5_PIGIg-like domain-containing protein. (154 aa)
SLA-DRB1Ig-like domain-containing protein. (307 aa)
A0A287BQ00_PIGIg-like domain-containing protein. (194 aa)
HLA-DRAMajor histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family. (252 aa)
CSKTyrosine-protein kinase. (474 aa)
PTPN22Protein tyrosine phosphatase non-receptor type 22. (821 aa)
CD4CD4 molecule. (494 aa)
I3LAQ5_PIGIg-like domain-containing protein. (164 aa)
PTPRJProtein tyrosine phosphatase receptor type J. (1340 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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