29 items (Sus scrofa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

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Your Input:
	FYB1	FYN binding protein 1. (837 aa)
	CD3D	T-cell surface glycoprotein CD3 delta chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of [...] (171 aa)
	PAK1	Non-specific serine/threonine protein kinase. (546 aa)
	ZAP70	Tyrosine-protein kinase. (615 aa)
	SPNS1	MFS domain-containing protein. (476 aa)
	A0A286ZKB7_PIG	Ig-like domain-containing protein. (259 aa)
	ITK	Tyrosine-protein kinase. (598 aa)
	GRAP2	GRB2-related adapter protein 2 isoform 1. (320 aa)
	A0A287AAB9_PIG	Ig-like domain-containing protein. (252 aa)
	A0A287AC24_PIG	Ig-like domain-containing protein. (112 aa)
	CD3G	T-cell surface glycoprotein CD3 gamma chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of [...] (176 aa)
	SLA-DQA1	SLA class II histocompatibility antigen, DQ haplotype D alpha chain. (255 aa)
	LCK	Tyrosine-protein kinase. (520 aa)
	A0A287ARF7_PIG	Ig-like domain-containing protein. (139 aa)
	A0A287AT33_PIG	Ig-like domain-containing protein. (173 aa)
	LOC102158035	Ig-like domain-containing protein. (268 aa)
	SLA-DRB1	Ig-like domain-containing protein. (307 aa)
	A0A287BPL5_PIG	Ig-like domain-containing protein. (154 aa)
	A0A287BQ00_PIG	Ig-like domain-containing protein. (194 aa)
	A0A287BQ31_PIG	Ig-like domain-containing protein. (180 aa)
	HLA-DRA	Major histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family. (252 aa)
	PLCG2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
	PLCG1	Phosphoinositide phospholipase C. (1379 aa)
	PAK2	Non-specific serine/threonine protein kinase. (524 aa)
	LCP2	Lymphocyte cytosolic protein 2. (532 aa)
	CD4	CD4 molecule. (494 aa)
	I3LAQ5_PIG	Ig-like domain-containing protein. (164 aa)
	NCK1	Cytoplasmic protein. (377 aa)
	CD101	CD101 molecule. (1018 aa)

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A286ZKB7_PIG	A0A287AAB9_PIG	ENSSSCP00000031912	ENSSSCP00000040841	Ig-like domain-containing protein.	Ig-like domain-containing protein.	0.552
A0A286ZKB7_PIG	A0A287AC24_PIG	ENSSSCP00000031912	ENSSSCP00000041569	Ig-like domain-containing protein.	Ig-like domain-containing protein.	0.595
A0A286ZKB7_PIG	A0A287ARF7_PIG	ENSSSCP00000031912	ENSSSCP00000046440	Ig-like domain-containing protein.	Ig-like domain-containing protein.	0.595
A0A286ZKB7_PIG	A0A287AT33_PIG	ENSSSCP00000031912	ENSSSCP00000047258	Ig-like domain-containing protein.	Ig-like domain-containing protein.	0.627
A0A286ZKB7_PIG	A0A287BPL5_PIG	ENSSSCP00000031912	ENSSSCP00000058045	Ig-like domain-containing protein.	Ig-like domain-containing protein.	0.627
A0A286ZKB7_PIG	A0A287BQ00_PIG	ENSSSCP00000031912	ENSSSCP00000058182	Ig-like domain-containing protein.	Ig-like domain-containing protein.	0.595
A0A286ZKB7_PIG	A0A287BQ31_PIG	ENSSSCP00000031912	ENSSSCP00000058284	Ig-like domain-containing protein.	Ig-like domain-containing protein.	0.740
A0A286ZKB7_PIG	CD3D	ENSSSCP00000031912	ENSSSCP00000028968	Ig-like domain-containing protein.	T-cell surface glycoprotein CD3 delta chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of [...]	0.562
A0A286ZKB7_PIG	CD3G	ENSSSCP00000031912	ENSSSCP00000043282	Ig-like domain-containing protein.	T-cell surface glycoprotein CD3 gamma chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of [...]	0.526
A0A286ZKB7_PIG	CD4	ENSSSCP00000031912	ENSSSCP00000019155	Ig-like domain-containing protein.	CD4 molecule.	0.692
A0A286ZKB7_PIG	GRAP2	ENSSSCP00000031912	ENSSSCP00000038513	Ig-like domain-containing protein.	GRB2-related adapter protein 2 isoform 1.	0.536
A0A286ZKB7_PIG	HLA-DRA	ENSSSCP00000031912	ENSSSCP00000001567	Ig-like domain-containing protein.	Major histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family.	0.874
A0A286ZKB7_PIG	I3LAQ5_PIG	ENSSSCP00000031912	ENSSSCP00000021123	Ig-like domain-containing protein.	Ig-like domain-containing protein.	0.612
A0A286ZKB7_PIG	ITK	ENSSSCP00000031912	ENSSSCP00000033531	Ig-like domain-containing protein.	Tyrosine-protein kinase.	0.543
A0A286ZKB7_PIG	LCK	ENSSSCP00000031912	ENSSSCP00000043318	Ig-like domain-containing protein.	Tyrosine-protein kinase.	0.543
A0A286ZKB7_PIG	LCP2	ENSSSCP00000031912	ENSSSCP00000018018	Ig-like domain-containing protein.	Lymphocyte cytosolic protein 2.	0.589
A0A286ZKB7_PIG	LOC102158035	ENSSSCP00000031912	ENSSSCP00000050109	Ig-like domain-containing protein.	Ig-like domain-containing protein.	0.527
A0A286ZKB7_PIG	PLCG1	ENSSSCP00000031912	ENSSSCP00000007834	Ig-like domain-containing protein.	Phosphoinositide phospholipase C.	0.408
A0A286ZKB7_PIG	SLA-DQA1	ENSSSCP00000031912	ENSSSCP00000070034	Ig-like domain-containing protein.	SLA class II histocompatibility antigen, DQ haplotype D alpha chain.	0.866
A0A286ZKB7_PIG	SLA-DRB1	ENSSSCP00000031912	ENSSSCP00000055121	Ig-like domain-containing protein.	Ig-like domain-containing protein.	0.548