STRINGSTRING
TEAD4 TEAD4 TEAD3 TEAD3 TBX5 TBX5 WWTR1 WWTR1 KAT2B KAT2B YAP1 YAP1 TEAD2 TEAD2 TEAD1 TEAD1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TEAD4Transcriptional enhancer factor TEF-3; Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. (497 aa)
TEAD3YBD domain-containing protein. (395 aa)
TBX5T-box transcription factor 5. (535 aa)
WWTR1WW domain containing transcription regulator 1. (398 aa)
KAT2BHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (831 aa)
YAP1Yes associated protein 1. (432 aa)
TEAD2TEA domain transcription factor 2. (457 aa)
TEAD1TEA domain transcription factor 1. (630 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.