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| | SULT4A1 | Sulfotransferase; Belongs to the sulfotransferase 1 family. (283 aa) |
| | PTGES3 | Prostaglandin E synthase 3. (160 aa) |
| | BPHL | AB hydrolase-1 domain-containing protein. (309 aa) |
| | TPMT | Thiopurine S-methyltransferase. (245 aa) |
| | GCLC | Glutamate--cysteine ligase catalytic subunit isoform X3. (588 aa) |
| | SLC35B2 | Solute carrier family 35 member B2. (432 aa) |
| | CYP1A2 | Cytochrome P450 family 1 subfamily A member 2; Belongs to the cytochrome P450 family. (516 aa) |
| | CYP1A1 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. (538 aa) |
| | CYP46A1 | Cytochrome P450 family 46 subfamily A member 1; Belongs to the cytochrome P450 family. (501 aa) |
| | GSTA4 | Glutathione S-transferase alpha 4. (223 aa) |
| | CES1-2 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (530 aa) |
| | CYP2A19 | Cytochorme P450 2A19; Belongs to the cytochrome P450 family. (494 aa) |
| | CYP2F1 | Cytochrome P450 family 2 subfamily F member 1; Belongs to the cytochrome P450 family. (492 aa) |
| | CYP2B22 | Uncharacterized protein; Belongs to the cytochrome P450 family. (529 aa) |
| | AKR7A2 | Aflatoxin B1 aldehyde reductase member 4. (369 aa) |
| | CYP4A24 | Cytochrome P450 4A24; Catalyzes the omega- and (omega-1)-hydroxylation of various fatty acids such as laurate and palmitate. Has no activity toward taurochenodeoxycholic acid; Belongs to the cytochrome P450 family. (482 aa) |
| | CNDP2 | Cytosolic non-specific dipeptidase isoform X1. (475 aa) |
| | ALDH1B1 | Aldehyde dehydrogenase 1 family member B1; Belongs to the aldehyde dehydrogenase family. (517 aa) |
| | OPLAH | 5-oxoprolinase, ATP-hydrolysing. (1287 aa) |
| | CYP7B1 | Cytochrome P450 family 7 subfamily B member 1; Belongs to the cytochrome P450 family. (510 aa) |
| | MGST3 | Microsomal glutathione S-transferase 3. (151 aa) |
| | GSTM3 | Glutathione S-transferase. (225 aa) |
| | F1SE17_PIG | Uncharacterized protein; Belongs to the arylamine N-acetyltransferase family. (307 aa) |
| | A0A480RQR3_PIG | Arylamine N-acetyltransferase 1 isoform b; Belongs to the arylamine N-acetyltransferase family. (334 aa) |
| | SMOX | Spermine oxidase. (585 aa) |
| | GGT7 | Gamma-glutamyltransferase 7. (662 aa) |
| | PTGIS | Prostacyclin synthase; Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2); Belongs to the cytochrome P450 family. (503 aa) |
| | CYP24A1 | 25-hydroxyvitamin D3-24-hydroxylase; Belongs to the cytochrome P450 family. (514 aa) |
| | CYP2W1 | Cytochrome P450 family 2 subfamily W member 1; Belongs to the cytochrome P450 family. (469 aa) |
| | ACSM2B | Uncharacterized protein. (578 aa) |
| | CYP26B1 | Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. (512 aa) |
| | ADH4 | Alcohol dehydrogenase 4 isoform 2. (380 aa) |
| | HPGDS | Hematopoietic prostaglandin D synthase. (199 aa) |
| | ALDH2 | Aldehyde dehydrogenase, mitochondrial; Is capable of converting retinaldehyde to retinoic acid. (537 aa) |
| | MTR | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1265 aa) |
| | MAT1A | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (407 aa) |
| | CYP26C1 | Cytochrome P450 family 26 subfamily C member 1; Belongs to the cytochrome P450 family. (522 aa) |
| | CYP26A1 | Cytochrome P450 family 26 subfamily A member 1; Belongs to the cytochrome P450 family. (497 aa) |
| | AS3MT | Arsenite methyltransferase. (395 aa) |
| | GSTO1 | Glutathione S-transferase omega-1; Exhibits glutathione-dependent thiol transferase and dehydroascorbate reductase activities. Has S-(phenacyl)glutathione reductase activity. Has also glutathione S-transferase activity. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA) and dimethylarsonic acid. Belongs to the GST superfamily. Omega family. (241 aa) |
| | GSTO2 | Glutathione S-transferase omega 2; Belongs to the GST superfamily. (244 aa) |
| | BPNT1 | 3'(2'), 5'-bisphosphate nucleotidase 1. (354 aa) |
| | EPHX1 | Epoxide hydrolase 1; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. May play a role in the metabolism of endogenous lipids such as epoxide-containing fatty acids. Belongs to the peptidase S33 family. (452 aa) |
| | F1SL35_PIG | Uncharacterized protein; Belongs to the GST superfamily. (256 aa) |
| | CBR3 | Carbonyl reductase NADPH 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (277 aa) |
| | AIP | Aryl hydrocarbon receptor interacting protein. (330 aa) |
| | SLC26A2 | Sulfate transporter; Sulfate transporter. May play a role in endochondral bone formation; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (739 aa) |
| | FMO2 | Dimethylaniline monooxygenase [N-oxide-forming]. (535 aa) |
| | UGT1A6 | UDPGT domain-containing protein; Belongs to the UDP-glycosyltransferase family. (815 aa) |
| | TBXAS1 | Thromboxane-A synthase; Belongs to the cytochrome P450 family. (535 aa) |
| | AOC2 | Amine oxidase. (755 aa) |
| | GGT6 | Gamma-glutamyltransferase 6. (551 aa) |
| | DPEP1 | Dipeptidase 1; Hydrolyzes a wide range of dipeptides. Implicated in the renal metabolism of glutathione and its conjugates. Converts leukotriene D4 to leukotriene E4; it may play an important role in the regulation of leukotriene activity; Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family. (409 aa) |
| | ACSM5 | Acyl-coenzyme A synthetase ACSM5, mitochondrial isoform 1. (579 aa) |
| | N6AMT1 | N-6 adenine-specific DNA methyltransferase 1. (220 aa) |
| | SULT1C2 | Sulfotransferase; Belongs to the sulfotransferase 1 family. (296 aa) |
| | CYP27A1 | Uncharacterized protein; Belongs to the cytochrome P450 family. (581 aa) |
| | DPEP3 | Dipeptidase; Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family. (555 aa) |
| | AHR | Aryl hydrocarbon receptor. (849 aa) |
| | CYP27B1 | Cytochrome P450 family 27 subfamily B member 1; Belongs to the cytochrome P450 family. (500 aa) |
| | CYP11A1 | Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R-hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the sec [...] (520 aa) |
| | UGDH | UDP-glucose 6-dehydrogenase; Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate. Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (494 aa) |
| | CYP4F22 | Cytochrome P450 family 4 subfamily F member 22; Belongs to the cytochrome P450 family. (531 aa) |
| | SULT1A3 | Sulfotransferase; Belongs to the sulfotransferase 1 family. (284 aa) |
| | SULT2B1 | Sulfotransferase; Belongs to the sulfotransferase 1 family. (338 aa) |
| | ALDH1A1 | Aldehyde dehydrogenase 1 family member A1; Belongs to the aldehyde dehydrogenase family. (501 aa) |
| | ACSM4 | Acyl-CoA synthetase medium chain family member 4. (580 aa) |
| | CYP2J34 | Uncharacterized protein; Belongs to the cytochrome P450 family. (554 aa) |
| | PAPSS2 | Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 isoform b. (620 aa) |
| | NQO2 | N-ribosyldihydronicotinamide:quinone reductase 2. (239 aa) |
| | HSP90AB1 | Heat shock protein 90 alpha family class B member 1. (825 aa) |
| | ARNT2 | Aryl hydrocarbon receptor nuclear translocator 2. (892 aa) |
| | LOC100520329 | Amine oxidase. (742 aa) |
| | ALDH3A1 | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (527 aa) |
| | FDX1 | Adrenodoxin, mitochondrial; Essential for the synthesis of various steroid hormones. Participates in the reduction of mitochondrial cytochrome P450 for steroidogenesis. Transfers electrons from adrenodoxin reductase to CYP11A1, a cytochrome P450 that catalyzes cholesterol side-chain cleavage. Does not form a ternary complex with adrenodoxin reductase and CYP11A1 but shuttles between the two enzymes to transfer electrons. Belongs to the adrenodoxin/putidaredoxin family. (186 aa) |
| | CYP7A1 | Cytochrome P450 7A1; A cytochrome P450 monooxygenase involved in the metabolism of endogenous cholesterol and its oxygenated derivatives (oxysterols). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH- ferrihemoprotein reductase). Functions as a critical regulatory enzyme of bile acid biosynthesis and cholesterol homeostasis. Catalyzes the hydroxylation of carbon hydrogen bond at 7-alpha position of cholesterol, a rate-limiting s [...] (554 aa) |
| | GSS | Glutathione synthetase. (474 aa) |
| | SULT1E1 | Sulfotransferase; Belongs to the sulfotransferase 1 family. (296 aa) |
| | CHAC1 | Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (219 aa) |
| | CYP2U1 | Cytochrome P450 family 2 subfamily U member 1; Belongs to the cytochrome P450 family. (543 aa) |
| | MAT2A | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (395 aa) |
| | AOC1 | Amiloride-sensitive amine oxidase [copper-containing]; Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis; Belongs to the copper/topaquinone oxidase family. (726 aa) |
| | MGST1 | Microsomal glutathione S-transferase 1; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles; Belongs to the MAPEG family. (155 aa) |
| | PAOX | Amino_oxidase domain-containing protein. (512 aa) |
| | CMBL | Carboxymethylenebutenolidase homolog. (245 aa) |
| | PAPSS1 | 3'-phosphoadenosine 5'-phosphosulfate synthase 1. (808 aa) |
| | CYP2S1 | Cytochrome P450 family 2 subfamily S member 1; Belongs to the cytochrome P450 family. (650 aa) |
| | GCLM | Glutamate--cysteine ligase regulatory subunit. (274 aa) |
| | IMPAD1 | Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase; Exhibits 3'-nucleotidase activity toward adenosine 3',5'- bisphosphate (PAP), namely hydrolyzes adenosine 3',5'-bisphosphate into adenosine 5'-monophosphate (AMP) and a phosphate. May play a role in the formation of skeletal elements derived through endochondral ossification, possibly by clearing adenosine 3',5'-bisphosphate produced by Golgi sulfotransferases during glycosaminoglycan sulfation. Has no activity toward 3'-phosphoadenosine 5'-phosphosulfate (PAPS) or inositol phosphate (IP) substrates including I(1)P, I(1,4)P2, [...] (359 aa) |
| | CYP2R1 | Cytochrome P450 family 2 subfamily R member 1; Belongs to the cytochrome P450 family. (500 aa) |
| | CYP51A1 | Lanosterol 14-alpha demethylase; A cytochrome P450 monooxygenase involved in sterol biosynthesis. Catalyzes 14-alpha demethylation of lanosterol and 24,25- dihydrolanosterol likely through sequential oxidative conversion of 14- alpha methyl group to hydroxymethyl, then to carboxylaldehyde, followed by the formation of the delta 14,15 double bond in the sterol core and concomitant release of formic acid. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P45 [...] (503 aa) |
| | SULT1B1 | Sulfotransferase; Belongs to the sulfotransferase 1 family. (296 aa) |
| | NCOA2 | Nuclear receptor coactivator. (1463 aa) |
| | CYP4B1 | Cytochrome P450 family 4 subfamily B member 1; Belongs to the cytochrome P450 family. (459 aa) |
| | ABHD10 | Abhydrolase domain containing 10. (306 aa) |
| | AHRR | Uncharacterized protein. (695 aa) |
| | PTGS1 | Prostaglandin G/H synthase 1 isoform 1. (600 aa) |
| | FDXR | NADPH:adrenodoxin oxidoreductase, mitochondrial. (520 aa) |
| | ACSS1 | Acetyl-coenzyme A synthetase. (703 aa) |
| | SLC26A1 | Sulfate anion transporter 1; Mediates sulfate transport with high affinity. Mediates oxalate transport. Mediates bicarbonate transport. Does not accept succinate as cosubstrate; Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (706 aa) |
| | SULT1C4 | Sulfotransferase; Belongs to the sulfotransferase 1 family. (324 aa) |
| | SULT2A1 | Sulfotransferase; Belongs to the sulfotransferase 1 family. (285 aa) |
| | AADAC | Arylacetamide deacetylase. (399 aa) |
| | ADH5 | S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (392 aa) |
| | TPST2 | Protein-tyrosine sulfotransferase; Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate; Belongs to the protein sulfotransferase family. (338 aa) |
| | CYP4V2 | Cytochrome P450 family 4 subfamily V member 2; Belongs to the cytochrome P450 family. (525 aa) |
| | ESD | S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (282 aa) |
| | DPEP2 | Dipeptidase; Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family. (557 aa) |
| | CHAC2 | Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (189 aa) |
| | MTRR | 5-methyltetrahydrofolate-homocysteine methyltransferase reductase. (737 aa) |
| | FMO1 | Dimethylaniline monooxygenase [N-oxide-forming] 1; This protein is involved in the oxidative metabolism of a variety of xenobiotics such as drugs and pesticides. (554 aa) |
| | MTARC1 | Mitochondrial amidoxime-reducing component 1. (341 aa) |
| | TRMT112 | Multifunctional methyltransferase subunit TRM112-like protein isoform X1. (154 aa) |
| | ACSS2 | Acetyl-coenzyme A synthetase, cytoplasmic isoform X1. (714 aa) |
| | FMO3 | Dimethylaniline monooxygenase [N-oxide-forming]. (532 aa) |
| | SULT6B1 | Sulfotransferase; Belongs to the sulfotransferase 1 family. (303 aa) |
| | CYP1B1 | Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (543 aa) |
| | CYP4F3 | Cytochrome P450 family 4 subfamily F member 3; Belongs to the cytochrome P450 family. (524 aa) |
| | CYP39A1 | Uncharacterized protein; Belongs to the cytochrome P450 family. (461 aa) |
| | PODXL2 | Podocalyxin like 2. (691 aa) |
| | TPST1 | Protein-tyrosine sulfotransferase; Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate; Belongs to the protein sulfotransferase family. (370 aa) |
| | MGST2 | Microsomal glutathione S-transferase 2. (146 aa) |
| | GGT5 | Gamma-glutamyltransferase 5. (639 aa) |
| | ADH1C | PKS_ER domain-containing protein. (388 aa) |
| | GSTK1 | DSBA domain-containing protein. (243 aa) |
| | SLC35B3 | Solute carrier family 35 member B3. (409 aa) |
| | CYP21A2 | Steroid 21-hydroxylase; Specifically catalyzes the 21-hydroxylation of steroids. Required for the adrenal synthesis of mineralocorticoids and glucocorticoids. (526 aa) |
| | NR1H4 | Nuclear receptor subfamily 1 group H member 4. (509 aa) |
| | MAT2B | Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. (370 aa) |
| | CYB5B | Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. (148 aa) |
| | CES3 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (571 aa) |
| | RXRA | Retinoid X receptor alpha. (701 aa) |
| | LOC110256000 | Amine oxidase; Belongs to the copper/topaquinone oxidase family. (751 aa) |
| | A0A5G2R4D9_PIG | Glutathione S-transferase. (348 aa) |
| | GSTZ1 | Glutathione S-transferase zeta 1; Belongs to the GST superfamily. (247 aa) |
| | GGCT | Uncharacterized protein. (188 aa) |
| | ACY1 | Aminoacylase-1; Involved in the hydrolysis of N-acylated or N-acetylated amino acids (except L-aspartate); Belongs to the peptidase M20A family. (437 aa) |
