STRINGSTRING
SEC24A SEC24A RACGAP1 RACGAP1 KIF5A KIF5A LAG3 LAG3 HLA-DRA HLA-DRA HLA-DOB HLA-DOB SLA-DMB SLA-DMB SLA-DOA SLA-DOA KIFC1 KIFC1 KIF6 KIF6 KLC4 KLC4 CTSH CTSH SEC23A SEC23A LGMN LGMN KLC1 KLC1 AP2A1 AP2A1 OSBPL1A OSBPL1A KIF2C KIF2C F1SBY7_PIG F1SBY7_PIG KIF23 KIF23 SH3GL2 SH3GL2 CTSS CTSS CAPZA1 CAPZA1 TUBB1 TUBB1 SEC24D SEC24D SEC24B SEC24B KIF13B KIF13B DYNLL1 DYNLL1 AP1B1 AP1B1 SEC24C SEC24C KIF11 KIF11 DCTN3 DCTN3 KIF5B KIF5B LOC100127131 LOC100127131 CTSV CTSV CTSF CTSF KIF18A KIF18A CTSC CTSC KIF2B KIF2B KIF1C KIF1C AP2B1 AP2B1 DNM1 DNM1 LOC100510930 LOC100510930 AP1M2 AP1M2 KIF19 KIF19 KIF16B KIF16B ACTR10 ACTR10 KIF2A KIF2A DCTN4 DCTN4 CTSB CTSB KIF22 KIF22 KIF27 KIF27 KIF26B KIF26B SLA-DMA SLA-DMA A0A286ZKB7_PIG A0A286ZKB7_PIG DCTN5 DCTN5 RAB7A RAB7A DYNC1I2 DYNC1I2 AP2M1 AP2M1 ARF1 ARF1 ACTR1A ACTR1A TUBB4B TUBB4B DCTN6 DCTN6 CLTA CLTA AP1S3 AP1S3 DNM3 DNM3 AP1M1 AP1M1 A0A287AAB9_PIG A0A287AAB9_PIG SAR1B SAR1B KIFC2 KIFC2 DYNC1LI1 DYNC1LI1 KIF3B KIF3B CTSO CTSO KIF12 KIF12 KIF4A KIF4A CANX CANX KIF20B KIF20B DYNC1I1 DYNC1I1 CD74 CD74 SPTBN2 SPTBN2 TUBA8 TUBA8 TUBB6 TUBB6 TUBA1A TUBA1A KIFAP3 KIFAP3 CENPE CENPE KIF3C KIF3C DCTN1 DCTN1 DNM2 DNM2 KIF1B KIF1B AP1S2 AP1S2 KIF20A KIF20A SLA-DRB1 SLA-DRB1 KIF15 KIF15 DYNC1LI2 DYNC1LI2 KIF9 KIF9 CAPZA2 CAPZA2 KIF1A KIF1A CLTC CLTC KIF26A KIF26A RILP RILP ACTR1B ACTR1B KIF18B KIF18B SEC31A SEC31A AP1S1 AP1S1 AP1G1 AP1G1 AP2S1 AP2S1 KLC3 KLC3 SLA-DQA1 SLA-DQA1 AP2A2 AP2A2 DYNLL2 DYNLL2 CTSA CTSA KIF3A KIF3A TUBA4A TUBA4A A0A5G2R693_PIG A0A5G2R693_PIG DCTN2 DCTN2 SEC13 SEC13 KIF21A KIF21A TUBAL3 TUBAL3 KLC2 KLC2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SEC24ASEC24 homolog A, COPII coat complex component. (1133 aa)
RACGAP1Rac GTPase activating protein 1. (634 aa)
KIF5AKinesin family member 5A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1085 aa)
LAG3Uncharacterized protein. (507 aa)
HLA-DRAMajor histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family. (252 aa)
HLA-DOBHLA class II histocompatibility antigen, DO beta chain. (277 aa)
SLA-DMBMajor histocompatibility complex, class II, DM beta. (272 aa)
SLA-DOAIg-like domain-containing protein; Belongs to the MHC class II family. (360 aa)
KIFC1Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (704 aa)
KIF6Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (483 aa)
KLC4Kinesin light chain 4 isoform X1. (616 aa)
CTSHCathepsin H heavy chain; Important for the overall degradation of proteins in lysosomes; Belongs to the peptidase C1 family. (335 aa)
SEC23AProtein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (765 aa)
LGMNLegumain. (438 aa)
KLC1Uncharacterized protein. (677 aa)
AP2A1AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (977 aa)
OSBPL1AOxysterol-binding protein; Belongs to the OSBP family. (949 aa)
KIF2CKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (725 aa)
F1SBY7_PIGKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (442 aa)
KIF23Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (967 aa)
SH3GL2SH3 domain containing GRB2 like 2, endophilin A1. (352 aa)
CTSSCathepsin S; Belongs to the peptidase C1 family. (341 aa)
CAPZA1F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (294 aa)
TUBB1Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
SEC24DSEC24 homolog D, COPII coat complex component. (1033 aa)
SEC24BSEC24 homolog B, COPII coat complex component. (1258 aa)
KIF13BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (741 aa)
DYNLL1Dynein light chain. (89 aa)
AP1B1AP complex subunit beta. (949 aa)
SEC24CSEC24 homolog C, COPII coat complex component. (1118 aa)
KIF11Kinesin-like protein KIF11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1059 aa)
DCTN3Dynactin subunit 3 isoform 1. (186 aa)
KIF5BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (963 aa)
LOC100127131Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (474 aa)
CTSVCathepsin L1 heavy chain; Thiol protease important for the overall degradation of proteins in lysosomes (By similarity). Involved in the solubilization of cross-linked TG/thyroglobulin and in the subsequent release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen (By similarity). Belongs to the peptidase C1 family. (334 aa)
CTSFCathepsin F; Belongs to the peptidase C1 family. (474 aa)
KIF18AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (904 aa)
CTSCCathepsin C; Belongs to the peptidase C1 family. (463 aa)
KIF2BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (684 aa)
KIF1CKinesin family member 1C; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1101 aa)
AP2B1AP complex subunit beta. (957 aa)
DNM1Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (880 aa)
LOC100510930Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (469 aa)
AP1M2AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. (497 aa)
KIF19Kinesin-like protein KIF19; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1001 aa)
KIF16BKinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1879 aa)
ACTR10Actin-related protein 10; Belongs to the actin family. (417 aa)
KIF2AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (744 aa)
DCTN4Dynactin subunit 4. (501 aa)
CTSBCathepsin B heavy chain; Thiol protease which is believed to participate in intracellular degradation and turnover of proteins (By similarity). Cleaves matrix extracellular phosphoglycoprotein MEPE (By similarity). Involved in the solubilization of cross-linked TG/thyroglobulin in the thyroid follicle lumen (By similarity). Has also been implicated in tumor invasion and metastasis (By similarity). (416 aa)
KIF22Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (753 aa)
KIF27Kinesin family member 27; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1401 aa)
KIF26BKinesin family member 26B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (2109 aa)
SLA-DMAIg-like domain-containing protein; Belongs to the MHC class II family. (290 aa)
A0A286ZKB7_PIGIg-like domain-containing protein. (259 aa)
DCTN5Dynactin subunit 5. (182 aa)
RAB7ARAB7A, member RAS oncogene family. (252 aa)
DYNC1I2WD_REPEATS_REGION domain-containing protein. (581 aa)
AP2M1AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] (435 aa)
ARF1ADP ribosylation factor 1; Belongs to the small GTPase superfamily. Arf family. (211 aa)
ACTR1AActin related protein 1A. (369 aa)
TUBB4BTubulin beta 4B class IVb; Belongs to the tubulin family. (561 aa)
DCTN6Dynactin 6. (190 aa)
CLTAClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (242 aa)
AP1S3AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (154 aa)
DNM3Dynamin 3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (863 aa)
AP1M1AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. (483 aa)
A0A287AAB9_PIGIg-like domain-containing protein. (252 aa)
SAR1BGTP-binding protein SAR1b; Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Activated by the guanine nucleotide exchange factor PREB. Involved in the selection of the protein cargo and the assembly of the COPII coat complex (By similarity). (198 aa)
KIFC2Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (873 aa)
DYNC1LI1Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (524 aa)
KIF3BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (747 aa)
CTSOCathepsin O preproprotein; Belongs to the peptidase C1 family. (311 aa)
KIF12Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (651 aa)
KIF4AKinesin family member 4A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1195 aa)
CANXCalnexin. (615 aa)
KIF20BKinesin-like protein KIF20B isoform 2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1787 aa)
DYNC1I1Cytoplasmic dynein 1 intermediate chain 1 isoform X1. (645 aa)
CD74Thyroglobulin type-1 domain-containing protein. (347 aa)
SPTBN2Spectrin beta chain; Belongs to the spectrin family. (2423 aa)
TUBA8Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (497 aa)
TUBB6Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (411 aa)
TUBA1ADetyrosinated tubulin alpha-1B chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
KIFAP3Kinesin-associated protein 3 isoform X1. (809 aa)
CENPECentromere protein E; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (2733 aa)
KIF3CKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (798 aa)
DCTN1CAP-Gly domain-containing protein. (1281 aa)
DNM2Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (877 aa)
KIF1BKinesin family member 1B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1816 aa)
AP1S2AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (163 aa)
KIF20AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (890 aa)
SLA-DRB1Ig-like domain-containing protein. (307 aa)
KIF15Kinesin family member 15; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1395 aa)
DYNC1LI2Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (492 aa)
KIF9Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (885 aa)
CAPZA2F-actin-capping protein subunit alpha-2; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments (By similarity). (286 aa)
KIF1AKinesin family member 1A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1793 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1702 aa)
KIF26AKinesin family member 26A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1867 aa)
RILPRab interacting lysosomal protein. (362 aa)
ACTR1BActin related protein 1B; Belongs to the actin family. (375 aa)
KIF18BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (859 aa)
SEC31ASEC31 homolog A, COPII coat complex component. (1251 aa)
AP1S1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (163 aa)
AP1G1AP-1 complex subunit gamma. (825 aa)
AP2S1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (145 aa)
KLC3Kinesin light chain 3. (549 aa)
SLA-DQA1SLA class II histocompatibility antigen, DQ haplotype D alpha chain. (255 aa)
AP2A2Adaptor related protein complex 2 subunit alpha 2. (1108 aa)
DYNLL2Dynein light chain. (133 aa)
CTSACarboxypeptidase; Belongs to the peptidase S10 family. (485 aa)
KIF3AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (754 aa)
TUBA4ATubulin alpha 4a; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (618 aa)
A0A5G2R693_PIGTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (517 aa)
DCTN2Dynactin subunit 2. (408 aa)
SEC13SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family. (341 aa)
KIF21AKinesin family member 21A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1673 aa)
TUBAL3Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa)
KLC2Ras-related protein Rab-1B. (865 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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