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| | LMNB1 | Lamin-B1 isoform 1; Belongs to the intermediate filament family. (586 aa) |
| | CDC23 | Cell division cycle protein 23 homolog. (594 aa) |
| | EED | Embryonic ectoderm development. (466 aa) |
| | MAPKAPK2 | MAPK activated protein kinase 2; Belongs to the protein kinase superfamily. (361 aa) |
| | POT1 | Protection of telomeres 1. (813 aa) |
| | CBX4 | Chromobox 4. (547 aa) |
| | LOC100521680 | Histone H3.3; Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in [...] (136 aa) |
| | MAP2K6 | Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (339 aa) |
| | SUZ12 | SUZ12 polycomb repressive complex 2 subunit. (737 aa) |
| | ANAPC7 | Anaphase promoting complex subunit 7. (597 aa) |
| | EP400 | E1A binding protein p400. (3210 aa) |
| | I3LAJ9_PIG | Histone H2B; Belongs to the histone H2B family. (168 aa) |
| | PHC1 | Uncharacterized protein. (1001 aa) |
| | CDK4 | Cyclin-dependent kinase 4; Ser/Thr-kinase component of cyclin D-CDK4 (DC) complexes that phosphorylate and inhibit members of the retinoblastoma (RB) protein family including RB1 and regulate the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complexes and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. [...] (303 aa) |
| | ANAPC4 | Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (809 aa) |
| | HIST1H2BD | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | PHC2 | Polyhomeotic-like protein 2 isoform a. (887 aa) |
| | LOC100158121 | Histone H2A; Belongs to the histone H2A family. (130 aa) |
| | CBX2 | Chromobox protein homolog 2 isoform X1. (531 aa) |
| | LOC100621389 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (473 aa) |
| | CDK6 | Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa) |
| | MAPK11 | Mitogen-activated protein kinase. (364 aa) |
| | HMGA1 | High mobility group AT-hook 1. (180 aa) |
| | UBE2S | Ubiquitin conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family. (223 aa) |
| | P14ARF | ANK_REP_REGION domain-containing protein. (159 aa) |
| | A0A286ZRB3_PIG | Histone domain-containing protein. (130 aa) |
| | HIRA | Protein HIRA; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. (1009 aa) |
| | MAP3K5 | Mitogen-activated protein kinase kinase kinase 5. (1425 aa) |
| | CBX6 | Chromobox 6. (414 aa) |
| | MAP2K3 | Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (441 aa) |
| | RPS6KA2 | Ribosomal protein S6 kinase. (759 aa) |
| | ANAPC1 | Anaphase promoting complex subunit 1. (1944 aa) |
| | CDC26 | Cell division cycle 26. (107 aa) |
| | H1-4 | Histone cluster 1 H1 family member e. (207 aa) |
| | ETS2 | Protein C-ets-2; Transcription factor; Belongs to the ETS family. (470 aa) |
| | UBE2D1 | Ubiquitin-conjugating enzyme E2 D1 isoform 1; Belongs to the ubiquitin-conjugating enzyme family. (147 aa) |
| | H2BC11 | Histone H2B; Belongs to the histone H2B family. (149 aa) |
| | MAPKAPK3 | Mitogen-activated protein kinase-activated protein kinase 3; Belongs to the protein kinase superfamily. (384 aa) |
| | ID1 | Inhibitor of DNA binding 1, dominant negative helix-loop-helix protein. (154 aa) |
| | CDKN1C | Cyclin dependent kinase inhibitor 1C. (262 aa) |
| | RNF2 | Ring finger protein 2. (368 aa) |
| | RPS6KA1 | Ribosomal protein S6 kinase. (856 aa) |
| | MAPK7 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (840 aa) |
| | TERF1 | Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (436 aa) |
| | CDKN1B | p27Kip1. (198 aa) |
| | H2AJ | Histone H2A; Belongs to the histone H2A family. (129 aa) |
| | CEBPB | CCAAT/enhancer-binding protein. (346 aa) |
| | PHC3 | Polyhomeotic-like protein 3 isoform X1. (1011 aa) |
| | EZH2 | Enhancer of zeste 2 polycomb repressive complex 2 subunit. (762 aa) |
| | ACD | ACD shelterin complex subunit and telomerase recruitment factor. (477 aa) |
| | RPS27A | Ubiquitin-like domain-containing protein. (204 aa) |
| | CDK2 | Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (381 aa) |
| | LOC100152135 | Histone H2B; Belongs to the histone H2B family. (127 aa) |
| | LOC100152878 | Histone H2B; Belongs to the histone H2B family. (127 aa) |
| | EHMT2 | Uncharacterized protein. (1233 aa) |
| | RING1 | Ring finger protein 1. (406 aa) |
| | CDKN1A | Cyclin dependent kinase inhibitor 1A. (163 aa) |
| | TINF2 | TERF1 interacting nuclear factor 2. (455 aa) |
| | TERF2IP | TERF2 interacting protein. (401 aa) |
| | TERF2 | Telomeric repeat-binding factor 2. (542 aa) |
| | CCNE1 | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (410 aa) |
| | CDKN2C | Cyclin-dependent kinase 4 inhibitor C. (168 aa) |
| | SCMH1 | Scm polycomb group protein homolog 1. (647 aa) |
| | ASF1A | Anti-silencing function 1A histone chaperone. (204 aa) |
| | CDKN2B | Cyclin dependent kinase inhibitor 2B. (131 aa) |
| | CCNE2 | G1/S-specific cyclin-E2 isoform X1; Belongs to the cyclin family. (405 aa) |
| | H2AC20 | Histone H2A; Belongs to the histone H2A family. (129 aa) |
| | LOC102159655 | Histone H2A; Belongs to the histone H2A family. (130 aa) |
| | UBE2C | Ubiquitin conjugating enzyme E2 C; Belongs to the ubiquitin-conjugating enzyme family. (179 aa) |
| | UBN1 | Ubinuclein 1. (1133 aa) |
| | MAP4K4 | Mitogen-activated protein kinase kinase kinase kinase 4. (1378 aa) |
| | F1RWC9_PIG | Histone domain-containing protein. (142 aa) |
| | H2AFZ | Histone H2A; Belongs to the histone H2A family. (128 aa) |
| | CCNA1 | Cyclin-A1 isoform X1; Belongs to the cyclin family. (421 aa) |
| | RB1 | RB transcriptional corepressor 1. (938 aa) |
| | ANAPC5 | Anaphase-promoting complex subunit 5 isoform X1. (755 aa) |
| | MAPKAPK5 | Protein kinase domain-containing protein. (543 aa) |
| | LOC100155267 | Histone domain-containing protein; Belongs to the histone H2B family. (126 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (411 aa) |
| | BMI1 | RING-type domain-containing protein. (336 aa) |
| | MAP2K7 | Mitogen-activated protein kinase kinase 7. (465 aa) |
| | KXD1 | Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be in [...] (305 aa) |
| | RPS6KA3 | Ribosomal protein S6 kinase. (744 aa) |
| | MAP2K4 | Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (411 aa) |
| | CDC16 | TPR_REGION domain-containing protein. (680 aa) |
| | H2AZ2 | Histone H2A; Belongs to the histone H2A family. (145 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (568 aa) |
| | RBBP7 | RB binding protein 7, chromatin remodeling factor. (469 aa) |
| | H2BU1 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | NBN | Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (752 aa) |
| | ANAPC15 | Anaphase promoting complex subunit 15. (125 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (442 aa) |
| | FZR1 | Fizzy and cell division cycle 20 related 1. (493 aa) |
| | ANAPC2 | Anaphase promoting complex subunit 2; Belongs to the cullin family. (882 aa) |
| | H2AC6 | Histone H2A; Belongs to the histone H2A family. (145 aa) |
| | TNIK | TRAF2 and NCK-interacting protein kinase isoform 1. (1389 aa) |
| | HIST1H3E | Histone H3; Belongs to the histone H3 family. (136 aa) |
| | A0A287BCA6_PIG | Thioredoxin domain-containing protein. (99 aa) |
| | LOC102160336 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (206 aa) |
| | LOC100620620 | Histone H2A; Belongs to the histone H2A family. (113 aa) |
| | MRE11 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (708 aa) |
| | H2BC21 | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | EHMT1 | Euchromatic histone lysine methyltransferase 1. (1299 aa) |
| | CDC27 | Cell division cycle 27. (825 aa) |
| | CABIN1 | Calcineurin binding protein 1. (2222 aa) |
| | KDM6B | Lysine demethylase 6B. (1638 aa) |
| | CBX8 | Uncharacterized protein. (456 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (361 aa) |
| | RAD50 | Zinc-hook domain-containing protein. (1358 aa) |
| | H1-0 | H1 histone family member 0. (194 aa) |
| | ANAPC16 | Anaphase promoting complex subunit 16. (85 aa) |
| | H2AX | Histone H2A; Belongs to the histone H2A family. (143 aa) |
| | MAPK9 | Mitogen-activated protein kinase 9. (461 aa) |
| | HMGA2 | Uncharacterized protein. (143 aa) |
| | ETS1 | ETS proto-oncogene 1, transcription factor. (621 aa) |
| | UBC | Ubiquitin-related; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repa [...] (837 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (360 aa) |
| | ANAPC11 | RING-type domain-containing protein. (411 aa) |
| | KAT5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (576 aa) |
