(12 nodes) Formation of Senescence-Associated Heterochromatin Foci (SAHF) network (Sus scrofa)

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second shell of interactors

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Predicted Interactions

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Your Input:
	H1-0	H1 histone family member 0. (194 aa)
	HMGA2	Uncharacterized protein. (143 aa)
	ASF1A	Anti-silencing function 1A histone chaperone. (204 aa)
	UBN1	Ubinuclein 1. (1133 aa)
	RB1	RB transcriptional corepressor 1. (938 aa)
	LMNB1	Lamin-B1 isoform 1; Belongs to the intermediate filament family. (586 aa)
	EP400	E1A binding protein p400. (3210 aa)
	HMGA1	High mobility group AT-hook 1. (180 aa)
	HIRA	Protein HIRA; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. (1009 aa)
	H1-4	Histone cluster 1 H1 family member e. (207 aa)
	TP53	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (442 aa)
	CABIN1	Calcineurin binding protein 1. (2222 aa)

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASF1A	CABIN1	ENSSSCP00000004586	ENSSSCP00000056440	Anti-silencing function 1A histone chaperone.	Calcineurin binding protein 1.	0.965
ASF1A	EP400	ENSSSCP00000004586	ENSSSCP00000020142	Anti-silencing function 1A histone chaperone.	E1A binding protein p400.	0.473
ASF1A	H1-0	ENSSSCP00000004586	ENSSSCP00000058906	Anti-silencing function 1A histone chaperone.	H1 histone family member 0.	0.552
ASF1A	H1-4	ENSSSCP00000004586	ENSSSCP00000037051	Anti-silencing function 1A histone chaperone.	Histone cluster 1 H1 family member e.	0.529
ASF1A	HIRA	ENSSSCP00000004586	ENSSSCP00000034110	Anti-silencing function 1A histone chaperone.	Protein HIRA; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family.	0.994
ASF1A	HMGA1	ENSSSCP00000004586	ENSSSCP00000032411	Anti-silencing function 1A histone chaperone.	High mobility group AT-hook 1.	0.511
ASF1A	HMGA2	ENSSSCP00000004586	ENSSSCP00000061245	Anti-silencing function 1A histone chaperone.	Uncharacterized protein.	0.519
ASF1A	LMNB1	ENSSSCP00000004586	ENSSSCP00000015156	Anti-silencing function 1A histone chaperone.	Lamin-B1 isoform 1; Belongs to the intermediate filament family.	0.508
ASF1A	RB1	ENSSSCP00000004586	ENSSSCP00000010032	Anti-silencing function 1A histone chaperone.	RB transcriptional corepressor 1.	0.421
ASF1A	TP53	ENSSSCP00000004586	ENSSSCP00000050664	Anti-silencing function 1A histone chaperone.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...]	0.430
ASF1A	UBN1	ENSSSCP00000004586	ENSSSCP00000008461	Anti-silencing function 1A histone chaperone.	Ubinuclein 1.	0.992
CABIN1	ASF1A	ENSSSCP00000056440	ENSSSCP00000004586	Calcineurin binding protein 1.	Anti-silencing function 1A histone chaperone.	0.965
CABIN1	EP400	ENSSSCP00000056440	ENSSSCP00000020142	Calcineurin binding protein 1.	E1A binding protein p400.	0.598
CABIN1	H1-0	ENSSSCP00000056440	ENSSSCP00000058906	Calcineurin binding protein 1.	H1 histone family member 0.	0.499
CABIN1	H1-4	ENSSSCP00000056440	ENSSSCP00000037051	Calcineurin binding protein 1.	Histone cluster 1 H1 family member e.	0.521
CABIN1	HIRA	ENSSSCP00000056440	ENSSSCP00000034110	Calcineurin binding protein 1.	Protein HIRA; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family.	0.968
CABIN1	HMGA1	ENSSSCP00000056440	ENSSSCP00000032411	Calcineurin binding protein 1.	High mobility group AT-hook 1.	0.531
CABIN1	HMGA2	ENSSSCP00000056440	ENSSSCP00000061245	Calcineurin binding protein 1.	Uncharacterized protein.	0.499
CABIN1	LMNB1	ENSSSCP00000056440	ENSSSCP00000015156	Calcineurin binding protein 1.	Lamin-B1 isoform 1; Belongs to the intermediate filament family.	0.403
CABIN1	RB1	ENSSSCP00000056440	ENSSSCP00000010032	Calcineurin binding protein 1.	RB transcriptional corepressor 1.	0.400