27 items (Sus scrofa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	COL11A1	Collagen type XI alpha 1 chain. (1816 aa)
	SDC3	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (417 aa)
	COL10A1	Type X collagen. (675 aa)
	COL5A1	Fibrillar collagen NC1 domain-containing protein. (1918 aa)
	SDC2	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (202 aa)
	DDR2	Discoidin domain receptor tyrosine kinase 2. (866 aa)
	COL4A2	Collagen type IV alpha 2 chain. (1712 aa)
	COL4A6	Collagen type IV alpha 6 chain. (1547 aa)
	COL5A3	Collagen type V alpha 3 chain. (1747 aa)
	COL1A2	Fibrillar collagen NC1 domain-containing protein. (1135 aa)
	FN1	Fibronectin 1. (2462 aa)
	ITGA2	Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1178 aa)
	PRKCA	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (669 aa)
	VTN	Vitronectin; Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway (By similarity). (523 aa)
	SDC1	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (309 aa)
	TGFB1	Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...] (390 aa)
	DDR1	Tyrosine-protein kinase receptor. (1005 aa)
	ITGAV	Integrin subunit alpha V; Belongs to the integrin alpha chain family. (1052 aa)
	ITGA6	Integrin subunit alpha 6; Belongs to the integrin alpha chain family. (1072 aa)
	COL2A1	Collagen type II alpha 1 chain. (1486 aa)
	SDC4	Syndecan-4; Cell surface proteoglycan that bears heparan sulfate. Regulates exosome biogenesis in concert with SDCBP and PDCD6IP. Belongs to the syndecan proteoglycan family. (353 aa)
	ITGB5	Integrin beta; Belongs to the integrin beta chain family. (800 aa)
	FGF2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (316 aa)
	COL11A2	Collagen type XI alpha 2 chain. (1796 aa)
	COL1A1	Collagen type I alpha 1 chain. (1477 aa)
	ITGB4	Integrin beta. (1814 aa)
	ITGB3	Integrin beta; Belongs to the integrin beta chain family. (835 aa)

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
COL10A1	COL11A1	ENSSSCP00000004785	ENSSSCP00000072487	Type X collagen.	Collagen type XI alpha 1 chain.	0.568
COL10A1	COL11A2	ENSSSCP00000004785	ENSSSCP00000059675	Type X collagen.	Collagen type XI alpha 2 chain.	0.590
COL10A1	COL1A1	ENSSSCP00000004785	ENSSSCP00000066291	Type X collagen.	Collagen type I alpha 1 chain.	0.588
COL10A1	COL1A2	ENSSSCP00000004785	ENSSSCP00000016253	Type X collagen.	Fibrillar collagen NC1 domain-containing protein.	0.577
COL10A1	COL2A1	ENSSSCP00000004785	ENSSSCP00000036099	Type X collagen.	Collagen type II alpha 1 chain.	0.681
COL10A1	COL4A2	ENSSSCP00000004785	ENSSSCP00000010191	Type X collagen.	Collagen type IV alpha 2 chain.	0.510
COL10A1	COL4A6	ENSSSCP00000004785	ENSSSCP00000013368	Type X collagen.	Collagen type IV alpha 6 chain.	0.494
COL10A1	COL5A1	ENSSSCP00000004785	ENSSSCP00000006161	Type X collagen.	Fibrillar collagen NC1 domain-containing protein.	0.586
COL10A1	COL5A3	ENSSSCP00000004785	ENSSSCP00000014530	Type X collagen.	Collagen type V alpha 3 chain.	0.610
COL10A1	TGFB1	ENSSSCP00000004785	ENSSSCP00000030317	Type X collagen.	Transforming growth factor beta-1 proprotein; Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively. Transforming growth factor beta-1: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form fo [...]	0.567
COL11A1	COL10A1	ENSSSCP00000072487	ENSSSCP00000004785	Collagen type XI alpha 1 chain.	Type X collagen.	0.568
COL11A1	COL11A2	ENSSSCP00000072487	ENSSSCP00000059675	Collagen type XI alpha 1 chain.	Collagen type XI alpha 2 chain.	0.879
COL11A1	COL1A1	ENSSSCP00000072487	ENSSSCP00000066291	Collagen type XI alpha 1 chain.	Collagen type I alpha 1 chain.	0.838
COL11A1	COL1A2	ENSSSCP00000072487	ENSSSCP00000016253	Collagen type XI alpha 1 chain.	Fibrillar collagen NC1 domain-containing protein.	0.786
COL11A1	COL2A1	ENSSSCP00000072487	ENSSSCP00000036099	Collagen type XI alpha 1 chain.	Collagen type II alpha 1 chain.	0.927
COL11A1	COL4A2	ENSSSCP00000072487	ENSSSCP00000010191	Collagen type XI alpha 1 chain.	Collagen type IV alpha 2 chain.	0.639
COL11A1	COL4A6	ENSSSCP00000072487	ENSSSCP00000013368	Collagen type XI alpha 1 chain.	Collagen type IV alpha 6 chain.	0.601
COL11A1	COL5A1	ENSSSCP00000072487	ENSSSCP00000006161	Collagen type XI alpha 1 chain.	Fibrillar collagen NC1 domain-containing protein.	0.551
COL11A1	COL5A3	ENSSSCP00000072487	ENSSSCP00000014530	Collagen type XI alpha 1 chain.	Collagen type V alpha 3 chain.	0.421
COL11A1	ITGB3	ENSSSCP00000072487	ENSSSCP00000072331	Collagen type XI alpha 1 chain.	Integrin beta; Belongs to the integrin beta chain family.	0.502