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I3LAJ9_PIG I3LAJ9_PIG HIST1H2BD HIST1H2BD LOC100621389 LOC100621389 JADE3 JADE3 JADE2 JADE2 A0A286ZRB3_PIG A0A286ZRB3_PIG JADE1 JADE1 MEAF6 MEAF6 H2BC11 H2BC11 BRD1 BRD1 NCOA2 NCOA2 ING5 ING5 H2BU1 H2BU1 ATF2 ATF2 HIST1H3E HIST1H3E H2BC21 H2BC21 KAT6A KAT6A KAT8 KAT8 MSL3 MSL3 MSL1 MSL1 H1-3 H1-3 ING4 ING4 KAT7 KAT7 BRPF3 BRPF3 RBBP7 RBBP7 LOC100152135 LOC100152135 LOC100152878 LOC100152878 LOC100155267 LOC100155267 KAT6B KAT6B BRPF1 BRPF1 MSL2 MSL2 HAT1 HAT1 PAX3 PAX3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
I3LAJ9_PIGHistone H2B; Belongs to the histone H2B family. (168 aa)
HIST1H2BDHistone H2B; Belongs to the histone H2B family. (126 aa)
LOC100621389Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
JADE3Jade family PHD finger 3. (833 aa)
JADE2Jade family PHD finger 2. (784 aa)
A0A286ZRB3_PIGHistone domain-containing protein. (130 aa)
JADE1Jade family PHD finger 1. (857 aa)
MEAF6MYST/Esa1 associated factor 6. (216 aa)
H2BC11Histone H2B; Belongs to the histone H2B family. (149 aa)
BRD1Bromodomain containing 1. (1187 aa)
NCOA2Nuclear receptor coactivator. (1463 aa)
ING5Inhibitor of growth family member 5. (273 aa)
H2BU1Histone H2B; Belongs to the histone H2B family. (126 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
HIST1H3EHistone H3; Belongs to the histone H3 family. (136 aa)
H2BC21Histone H2B; Belongs to the histone H2B family. (126 aa)
KAT6AHistone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (829 aa)
KAT8Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (461 aa)
MSL3MSL complex subunit 3. (606 aa)
MSL1MSL complex subunit 1. (624 aa)
H1-3Histone H2B; Belongs to the histone H2B family. (322 aa)
ING4Inhibitor of growth family member 4. (277 aa)
KAT7Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (613 aa)
BRPF3Bromodomain and PHD finger containing 3. (1150 aa)
RBBP7RB binding protein 7, chromatin remodeling factor. (469 aa)
LOC100152135Histone H2B; Belongs to the histone H2B family. (127 aa)
LOC100152878Histone H2B; Belongs to the histone H2B family. (127 aa)
LOC100155267Histone domain-containing protein; Belongs to the histone H2B family. (126 aa)
KAT6BHistone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (2065 aa)
BRPF1Uncharacterized protein. (1214 aa)
MSL2E3 ubiquitin-protein ligase MSL2 isoform 1. (577 aa)
HAT1Histone acetyltransferase type B catalytic subunit; Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. (418 aa)
PAX3Paired box protein Pax-3 isoform PAX3e. (484 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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