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| | CXCL11 | C-X-C motif chemokine. (129 aa) |
| | CXCL9 | C-X-C motif chemokine. (126 aa) |
| | TRHR | Thyrotropin-releasing hormone receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (398 aa) |
| | UTS2R | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (372 aa) |
| | GAL | Galanin message-associated peptide; Endocrine hormone of the central and peripheral nervous systems that binds and activates the G protein-coupled receptors GALR1, GALR2, and GALR3. This small neuropeptide may regulate diverse physiologic functions including contraction of smooth muscle of the gastrointestinal and genitourinary tract, growth hormone and insulin release and adrenal secretion; Belongs to the galanin family. (337 aa) |
| | ACKR1 | Atypical chemokine receptor 1 isoform b. (373 aa) |
| | F2RL2 | Coagulation factor II thrombin receptor like 2; Belongs to the G-protein coupled receptor 1 family. (378 aa) |
| | PROKR1 | Prokineticin receptor 1; Belongs to the G-protein coupled receptor 1 family. (393 aa) |
| | SST | Somatostatin-14; [Somatostatin-14]: Inhibits the secretion of pituitary hormones, including that of growth hormone/somatotropin (GH1), PRL, ACTH, luteinizing hormone (LH) and TSH. Also impairs ghrelin- and GnRH- stimulated secretion of GH1 and LH; the inhibition of ghrelin- stimulated secretion of GH1 can be further increased by neuronostatin. (116 aa) |
| | BRS3 | Bombesin receptor subtype 3; Belongs to the G-protein coupled receptor 1 family. (399 aa) |
| | NTSR1 | Neurotensin receptor 1; Belongs to the G-protein coupled receptor 1 family. (417 aa) |
| | UTS2B | Urotensin 2B. (119 aa) |
| | PNOC | Nociceptin. (203 aa) |
| | NLN | Neurolysin, mitochondrial; Binds angiotensins and its analogs; Belongs to the peptidase M3 family. (745 aa) |
| | KISS1 | KiSS-1 metastasis-suppressor. (138 aa) |
| | NMBR | Neuromedin B receptor; Belongs to the G-protein coupled receptor 1 family. (390 aa) |
| | TACR3 | Tachykinin receptor 3; Belongs to the G-protein coupled receptor 1 family. (463 aa) |
| | NPB | Uncharacterized protein. (176 aa) |
| | CXCR4 | C-X-C chemokine receptor type 4; Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Involved in the AKT signaling cascade (By similarity). Plays a role in regulation of cell migration, e.g. during wound healing. Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Binds bacterial lipopolysaccharide (LPS) et mediates LPS- induced inflammatory response, including TNF secretion by monocytes (By similarity). Inv [...] (353 aa) |
| | PRLH | Prolactin releasing hormone. (87 aa) |
| | CCL16 | C-C motif chemokine. (120 aa) |
| | CCR10 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (375 aa) |
| | ACKR2 | Atypical chemokine receptor 2; Belongs to the G-protein coupled receptor 1 family. (385 aa) |
| | CCRL2 | Chemokine C-C motif receptor-like 2; Receptor for CCL19 and chemerin/RARRES2. Does not appear to be a signaling receptor, but may have a role in modulating chemokine- triggered immune responses by capturing and internalizing CCL19 or by presenting RARRES2 ligand to CMKLR1, a functional signaling receptor. Plays a critical role for the development of Th2 responses (By similarity). (350 aa) |
| | CXCL12 | C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (119 aa) |
| | EDN3 | Endothelin-3; Endothelins are endothelium-derived vasoconstrictor peptides. Belongs to the endothelin/sarafotoxin family. (231 aa) |
| | CCL4 | C-C motif chemokine 4; Monokine with inflammatory and chemokinetic properties. (96 aa) |
| | CCL25 | C-C motif chemokine 25; Potentially involved in T-cell development. Recombinant protein shows chemotactic activity on thymocytes, macrophages, THP-1 cells, and dendritics cells but is inactive on peripheral blood lymphocytes and neutrophils. Binds to CCR9. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4 (By similarity); Belongs to the intercrine beta (chemokine CC) family. (220 aa) |
| | KEL | Kell metallo-endopeptidase (Kell blood group). (763 aa) |
| | NMUR1 | Neuromedin U receptor 1; Belongs to the G-protein coupled receptor 1 family. (556 aa) |
| | GALR1 | Galanin receptor 1; Belongs to the G-protein coupled receptor 1 family. (349 aa) |
| | APLN | Apelin. (77 aa) |
| | PPBP | Platelet basic protein; Chemoattractant factor for neutrophils. (159 aa) |
| | GPR37 | G protein-coupled receptor 37. (614 aa) |
| | NPW | Neuropeptide W-23; Plays a regulatory role in the organization of neuroendocrine signals accessing the anterior pituitary gland. Stimulates water drinking and food intake. May play a role in the hypothalamic response to stress (By similarity); Belongs to the neuropeptide B/W family. (152 aa) |
| | CCR5 | C-C motif chemokine receptor 5 (gene/pseudogene); Belongs to the G-protein coupled receptor 1 family. (361 aa) |
| | SSTR3 | Somatostatin receptor 3; Belongs to the G-protein coupled receptor 1 family. (421 aa) |
| | GALR3 | Galanin receptor 3; Belongs to the G-protein coupled receptor 1 family. (376 aa) |
| | NPFF | Neuropeptide FF-amide peptide precursor. (114 aa) |
| | TAC3 | Neurokinin-B; Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. Is a critical central regulator of gonadal function (By similarity); Belongs to the tachykinin family. (126 aa) |
| | PMCH | Pro-MCH preproprotein. (165 aa) |
| | NTS | Neurotensin/neuromedin N preproprotein. (171 aa) |
| | HCRTR2 | Orexin receptor type 2; Nonselective, high-affinity receptor for both orexin-A and orexin-B neuropeptides. Triggers an increase in cytoplasmic Ca(2+) levels in response to orexin-A binding. (444 aa) |
| | SSTR1 | Somatostatin receptor 1; Belongs to the G-protein coupled receptor 1 family. (354 aa) |
| | CCL22 | C-C motif chemokine. (93 aa) |
| | C5AR2 | Complement component 5a receptor 2. (434 aa) |
| | CORT | Somatostatin domain-containing protein. (108 aa) |
| | ECE1 | Endothelin converting enzyme 1. (771 aa) |
| | MCHR2 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (339 aa) |
| | QRFP | Pyroglutamylated RFamide peptide. (134 aa) |
| | PENK | Proenkephalin. (274 aa) |
| | OPRK1 | Opioid receptor kappa 1; Belongs to the G-protein coupled receptor 1 family. (380 aa) |
| | XCL1 | Lymphotactin isoform X1. (110 aa) |
| | RXFP4 | Relaxin-3/INSL7 receptor 2. (373 aa) |
| | PROK1 | Prokineticin 1. (105 aa) |
| | AVP | Vasopressin-neurophysin 2-copeptin. (217 aa) |
| | OXT | Oxytocin-neurophysin 1; Neurophysin 1 specifically binds oxytocin. (125 aa) |
| | MC3R | Melanocortin-3 receptor. (319 aa) |
| | NTSR2 | Neurotensin receptor 2; Belongs to the G-protein coupled receptor 1 family. (408 aa) |
| | NPY5R | Neuropeptide Y receptor type 5; Receptor for neuropeptide Y and peptide YY. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Seems to be associated with food intake. Could be involved in feeding disorders (By similarity); Belongs to the G-protein coupled receptor 1 family. (446 aa) |
| | NPFFR2 | Neuropeptide FF receptor 2; Belongs to the G-protein coupled receptor 1 family. (418 aa) |
| | CXCL8 | Interleukin-8; IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus; Belongs to the intercrine alpha (chemokine CxC) family. (103 aa) |
| | AMCF-II | Alveolar macrophage chemotactic factor 2; Has chemotactic activity for porcine, and in a lesser extent, for human neutrophils; Belongs to the intercrine alpha (chemokine CxC) family. (117 aa) |
| | QRFPR | Pyroglutamylated RFamide peptide receptor; Belongs to the G-protein coupled receptor 1 family. (431 aa) |
| | EDNRB | Endothelin receptor type B; Non-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. Endothelin receptor subfamily. EDNRB sub-subfamily. (443 aa) |
| | TACR2 | Tachykinin receptor 2; Belongs to the G-protein coupled receptor 1 family. (404 aa) |
| | NPFFR1 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (432 aa) |
| | PPYR1 | Neuropeptide Y-family receptor Y4; Belongs to the G-protein coupled receptor 1 family. (375 aa) |
| | NPS | Neuropeptide S. (89 aa) |
| | CCL19 | C-C motif chemokine. (100 aa) |
| | CCL27 | C-C motif chemokine 27. (107 aa) |
| | CCK | Cholecystokinin-58 desnonopeptide; This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion. (154 aa) |
| | CXCR6 | Chemokine (C-X-C motif) receptor 6; Belongs to the G-protein coupled receptor 1 family. (341 aa) |
| | CCR1 | Chemokine (C-C motif) receptor 1; Belongs to the G-protein coupled receptor 1 family. (354 aa) |
| | TRH | Pro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems. (241 aa) |
| | ACKR4 | Chemokine (C-C motif) receptor-like protein 1; Belongs to the G-protein coupled receptor 1 family. (350 aa) |
| | GRPR | Gastrin releasing peptide receptor; Belongs to the G-protein coupled receptor 1 family. (395 aa) |
| | AGTR2 | Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family. (362 aa) |
| | KISS1R | G protein-coupled receptor 54. (399 aa) |
| | RLN3 | Relaxin-3 A chain; May play a role in neuropeptide signaling processes. Ligand for LGR7, relaxin-3 receptor-1 and relaxin-3 receptor-2 (By similarity). (140 aa) |
| | INSL3 | Insulin-like 3 A chain; Seems to play a role in testicular function. May be a trophic hormone with a role in testicular descent in fetal life. Is a ligand for LGR8 receptor (By similarity); Belongs to the insulin family. (131 aa) |
| | F2RL1 | Proteinase-activated receptor 2 preproprotein. (397 aa) |
| | CXCR5 | C-X-C chemokine receptor type 5 isoform 1; Belongs to the G-protein coupled receptor 1 family. (373 aa) |
| | AVPR1B | Vasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (422 aa) |
| | F1SS05_PIG | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (343 aa) |
| | CXCR2 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (382 aa) |
| | ACKR3 | Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (362 aa) |
| | NPSR1 | Neuropeptide S receptor 1; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (369 aa) |
| | CCL28 | C-C motif chemokine. (176 aa) |
| | NMUR2 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (410 aa) |
| | SSTR2 | Somatostatin receptor type 2; Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 [...] (360 aa) |
| | HCRT | Orexin-A; Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Orexin-A binds to both OX1R and OX2R with a high affinity, whereas orexin-B binds only to OX2R with a similar high affinity (By similarity). (131 aa) |
| | CCR7 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (477 aa) |
| | CCL3L1 | C-C motif chemokine. (126 aa) |
| | CCL1 | C-C motif chemokine. (94 aa) |
| | CCL11 | C-C motif chemokine. (97 aa) |
| | CCL2 | C-C motif chemokine 2; Acts as a ligand for C-C chemokine receptor CCR2 (By similarity). Signals through binding and activation of CCR2 and induces a strong chemotactic response and mobilization of intracellular calcium ions (By similarity). Exhibits a chemotactic activity for monocytes and basophils but not neutrophils or eosinophils (By similarity). Plays an important role in mediating peripheral nerve injury-induced neuropathic pain (By similarity). Increases NMDA-mediated synaptic transmission in both dopamine D1 and D2 receptor-containing neurons, which may be caused by MAPK/ERK-d [...] (99 aa) |
| | CCL17 | C-C motif chemokine. (102 aa) |
| | CCR6 | C-C motif chemokine receptor 6; Belongs to the G-protein coupled receptor 1 family. (376 aa) |
| | CCKAR | Cholecystokinin A receptor; Belongs to the G-protein coupled receptor 1 family. (428 aa) |
| | MLNR | Motilin receptor; Belongs to the G-protein coupled receptor 1 family. (406 aa) |
| | PROK2 | Prokineticin 2. (129 aa) |
| | CCR8 | C-C motif chemokine receptor 8; Belongs to the G-protein coupled receptor 1 family. (379 aa) |
| | CCR2 | C-C chemokine receptor type 2 isoform B; Belongs to the G-protein coupled receptor 1 family. (373 aa) |
| | RXFP2 | Relaxin family peptide receptor 2. (737 aa) |
| | XCR1 | Chemokine XC receptor 1 isoform X1; Belongs to the G-protein coupled receptor 1 family. (333 aa) |
| | ECE2 | Uncharacterized protein. (1628 aa) |
| | GPER1 | G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (360 aa) |
| | GALR2 | Galanin receptor type 2; Belongs to the G-protein coupled receptor 1 family. (343 aa) |
| | C5AR1 | C5a anaphylatoxin chemotactic receptor 1; Belongs to the G-protein coupled receptor 1 family. (351 aa) |
| | CXCR3 | C-X-C chemokine receptor type 3 isoform 1; Belongs to the G-protein coupled receptor 1 family. (361 aa) |
| | F2RL3 | F2R like thrombin or trypsin receptor 3; Belongs to the G-protein coupled receptor 1 family. (382 aa) |
| | AGT | Angiotensinogen; Belongs to the serpin family. (482 aa) |
| | CCL20 | C-C motif chemokine. (153 aa) |
| | AGTR1 | Type-1 angiotensin II receptor; Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. (359 aa) |
| | PROKR2 | Prokineticin receptor 2; Belongs to the G-protein coupled receptor 1 family. (384 aa) |
| | XK | XK-related protein. (444 aa) |
| | CXCL10 | C-X-C motif chemokine. (104 aa) |
| | CCL8 | C-C motif chemokine 8; Chemotactic factor that attracts monocytes. This protein can bind heparin. (99 aa) |
| | TACR1 | Tachykinin receptor 1; Belongs to the G-protein coupled receptor 1 family. (394 aa) |
| | CCR4 | C-C chemokine receptor type 4 isoform X1; Belongs to the G-protein coupled receptor 1 family. (360 aa) |
| | SSTR5 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (305 aa) |
| | RXFP1 | Relaxin family peptide receptor 1. (785 aa) |
| | F2R | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (427 aa) |
| | AVPR1A | Vasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (423 aa) |
| | GPR37L1 | G protein-coupled receptor 37 like 1. (459 aa) |
| | CCL21 | Putative CCL21 chemokine. (134 aa) |
| | RXFP3 | G_PROTEIN_RECEP_F1_2 domain-containing protein. (458 aa) |
| | CCR9 | Chemokine (C-C motif) receptor 9 isoform A; Belongs to the G-protein coupled receptor 1 family. (369 aa) |
| | TAC1 | Tachykinin precursor 1. (130 aa) |
| | EDN2 | Endothelin 2. (180 aa) |
| | NPBWR2 | Neuropeptides B and W receptor 2; Belongs to the G-protein coupled receptor 1 family. (298 aa) |
| | CXCL13 | C-X-C motif chemokine. (111 aa) |
| | APLNR | Apelin receptor; Belongs to the G-protein coupled receptor 1 family. (383 aa) |
| | PRLHR | Prolactin releasing hormone receptor; Belongs to the G-protein coupled receptor 1 family. (370 aa) |
