Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ESR1 | MED1 | ENSSSCP00000030835 | ENSSSCP00000018552 | Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...] | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.975 |
| ESR1 | NCOR2 | ENSSSCP00000030835 | ENSSSCP00000010425 | Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...] | Uncharacterized protein. | 0.917 |
| ESR1 | NR5A2 | ENSSSCP00000030835 | ENSSSCP00000053785 | Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...] | Nuclear receptor subfamily 5 group A member 2. | 0.503 |
| ESR1 | PGR | ENSSSCP00000030835 | ENSSSCP00000015900 | Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...] | Progesterone receptor isoform B. | 0.965 |
| ESR1 | PPARG | ENSSSCP00000030835 | ENSSSCP00000012339 | Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...] | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | 0.659 |
| ESRRA | ESRRB | ENSSSCP00000013855 | ENSSSCP00000051043 | Steroid hormone receptor ERR1 isoform X1. | Estrogen related receptor beta. | 0.623 |
| ESRRA | ESRRG | ENSSSCP00000013855 | ENSSSCP00000053415 | Steroid hormone receptor ERR1 isoform X1. | Estrogen-related receptor gamma isoform 1. | 0.590 |
| ESRRA | MED1 | ENSSSCP00000013855 | ENSSSCP00000018552 | Steroid hormone receptor ERR1 isoform X1. | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.579 |
| ESRRA | NCOR2 | ENSSSCP00000013855 | ENSSSCP00000010425 | Steroid hormone receptor ERR1 isoform X1. | Uncharacterized protein. | 0.651 |
| ESRRA | PPARG | ENSSSCP00000013855 | ENSSSCP00000012339 | Steroid hormone receptor ERR1 isoform X1. | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | 0.660 |
| ESRRB | ESRRA | ENSSSCP00000051043 | ENSSSCP00000013855 | Estrogen related receptor beta. | Steroid hormone receptor ERR1 isoform X1. | 0.623 |
| ESRRB | ESRRG | ENSSSCP00000051043 | ENSSSCP00000053415 | Estrogen related receptor beta. | Estrogen-related receptor gamma isoform 1. | 0.475 |
| ESRRB | MED1 | ENSSSCP00000051043 | ENSSSCP00000018552 | Estrogen related receptor beta. | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.553 |
| ESRRB | NCOR2 | ENSSSCP00000051043 | ENSSSCP00000010425 | Estrogen related receptor beta. | Uncharacterized protein. | 0.749 |
| ESRRB | PGR | ENSSSCP00000051043 | ENSSSCP00000015900 | Estrogen related receptor beta. | Progesterone receptor isoform B. | 0.474 |
| ESRRB | PPARG | ENSSSCP00000051043 | ENSSSCP00000012339 | Estrogen related receptor beta. | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | 0.474 |
| ESRRG | ESRRA | ENSSSCP00000053415 | ENSSSCP00000013855 | Estrogen-related receptor gamma isoform 1. | Steroid hormone receptor ERR1 isoform X1. | 0.590 |
| ESRRG | ESRRB | ENSSSCP00000053415 | ENSSSCP00000051043 | Estrogen-related receptor gamma isoform 1. | Estrogen related receptor beta. | 0.475 |
| ESRRG | MED1 | ENSSSCP00000053415 | ENSSSCP00000018552 | Estrogen-related receptor gamma isoform 1. | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.553 |
| ESRRG | NCOR2 | ENSSSCP00000053415 | ENSSSCP00000010425 | Estrogen-related receptor gamma isoform 1. | Uncharacterized protein. | 0.749 |
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