(12 nodes) Rap1 signalling network (Sus scrofa)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RASGRP2	Uncharacterized protein. (881 aa)
	RAP1A	RAP1A, member of RAS oncogene family. (184 aa)
	YWHAB	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (264 aa)
	SIPA1	Signal-induced proliferation-associated 1. (1139 aa)
	RAPGEF3	Rap guanine nucleotide exchange factor 3 isoform a. (923 aa)
	RAP1GAP2	RAP1 GTPase activating protein 2. (850 aa)
	RAP1GAP	RAP1 GTPase activating protein. (754 aa)
	RAP1B	RAP1B, member of RAS oncogene family. (184 aa)
	PRKG1	cGMP-dependent protein kinase. (686 aa)
	RASGRP1	RAS guanyl releasing protein 1. (797 aa)
	YWHAZ	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; Belongs to the 14-3-3 family. (260 aa)
	RAPGEF4	Rap guanine nucleotide exchange factor 4. (995 aa)

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PRKG1	RAP1GAP2	ENSSSCP00000041950	ENSSSCP00000034735	cGMP-dependent protein kinase.	RAP1 GTPase activating protein 2.	0.772
RAP1A	RAP1B	ENSSSCP00000050852	ENSSSCP00000035670	RAP1A, member of RAS oncogene family.	RAP1B, member of RAS oncogene family.	0.925
RAP1A	RAP1GAP	ENSSSCP00000050852	ENSSSCP00000034901	RAP1A, member of RAS oncogene family.	RAP1 GTPase activating protein.	0.956
RAP1A	RAP1GAP2	ENSSSCP00000050852	ENSSSCP00000034735	RAP1A, member of RAS oncogene family.	RAP1 GTPase activating protein 2.	0.743
RAP1A	RAPGEF3	ENSSSCP00000050852	ENSSSCP00000020148	RAP1A, member of RAS oncogene family.	Rap guanine nucleotide exchange factor 3 isoform a.	0.925
RAP1A	RAPGEF4	ENSSSCP00000050852	ENSSSCP00000016912	RAP1A, member of RAS oncogene family.	Rap guanine nucleotide exchange factor 4.	0.914
RAP1A	RASGRP1	ENSSSCP00000050852	ENSSSCP00000005160	RAP1A, member of RAS oncogene family.	RAS guanyl releasing protein 1.	0.951
RAP1A	RASGRP2	ENSSSCP00000050852	ENSSSCP00000042669	RAP1A, member of RAS oncogene family.	Uncharacterized protein.	0.964
RAP1A	SIPA1	ENSSSCP00000050852	ENSSSCP00000062994	RAP1A, member of RAS oncogene family.	Signal-induced proliferation-associated 1.	0.913
RAP1A	YWHAB	ENSSSCP00000050852	ENSSSCP00000058156	RAP1A, member of RAS oncogene family.	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family.	0.629
RAP1A	YWHAZ	ENSSSCP00000050852	ENSSSCP00000006472	RAP1A, member of RAS oncogene family.	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; Belongs to the 14-3-3 family.	0.573
RAP1B	RAP1A	ENSSSCP00000035670	ENSSSCP00000050852	RAP1B, member of RAS oncogene family.	RAP1A, member of RAS oncogene family.	0.925
RAP1B	RAP1GAP	ENSSSCP00000035670	ENSSSCP00000034901	RAP1B, member of RAS oncogene family.	RAP1 GTPase activating protein.	0.981
RAP1B	RAP1GAP2	ENSSSCP00000035670	ENSSSCP00000034735	RAP1B, member of RAS oncogene family.	RAP1 GTPase activating protein 2.	0.755
RAP1B	RAPGEF3	ENSSSCP00000035670	ENSSSCP00000020148	RAP1B, member of RAS oncogene family.	Rap guanine nucleotide exchange factor 3 isoform a.	0.925
RAP1B	RAPGEF4	ENSSSCP00000035670	ENSSSCP00000016912	RAP1B, member of RAS oncogene family.	Rap guanine nucleotide exchange factor 4.	0.829
RAP1B	RASGRP1	ENSSSCP00000035670	ENSSSCP00000005160	RAP1B, member of RAS oncogene family.	RAS guanyl releasing protein 1.	0.955
RAP1B	RASGRP2	ENSSSCP00000035670	ENSSSCP00000042669	RAP1B, member of RAS oncogene family.	Uncharacterized protein.	0.976
RAP1B	SIPA1	ENSSSCP00000035670	ENSSSCP00000062994	RAP1B, member of RAS oncogene family.	Signal-induced proliferation-associated 1.	0.913
RAP1B	YWHAB	ENSSSCP00000035670	ENSSSCP00000058156	RAP1B, member of RAS oncogene family.	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family.	0.757