STRINGSTRING
ACKR3 ACKR3 TAS2R60 TAS2R60 OPN1SW OPN1SW ADCY1 ADCY1 CCL28 CCL28 NMUR2 NMUR2 ADCY2 ADCY2 SSTR2 SSTR2 PRKCA PRKCA CCR7 CCR7 CCL1 CCL1 CDK5 CDK5 HTR1F HTR1F LOC494564 LOC494564 ADCY5 ADCY5 GPSM2 GPSM2 CCR6 CCR6 TAS2R39 TAS2R39 TAS2R4 TAS2R4 TAS2R3 TAS2R3 ADRA2C ADRA2C GNG2 GNG2 CCR8 CCR8 CCR2 CCR2 GNG8 GNG8 SUCNR1 SUCNR1 GNAL GNAL GPER1 GPER1 GALR2 GALR2 OPN5 OPN5 C5AR1 C5AR1 CXCR3 CXCR3 AGT AGT SRC SRC CCL20 CCL20 RGS11 RGS11 GNB5 GNB5 RGS1 RGS1 PPP1CA PPP1CA CXCL10 CXCL10 GNG3 GNG3 PRKAR2B PRKAR2B RGS21 RGS21 CCR4 CCR4 SSTR5 SSTR5 ADCY7 ADCY7 RGS18 RGS18 TAS2R7 TAS2R7 GNAQ GNAQ GPR18 GPR18 GPR37L1 GPR37L1 LPAR2 LPAR2 CCL21 CCL21 RXFP3 RXFP3 CCR9 CCR9 GNB4 GNB4 P2RY13 P2RY13 PLCB4 PLCB4 LOC100154902 LOC100154902 GPR55 GPR55 RGS7 RGS7 NPBWR2 NPBWR2 CXCL13 CXCL13 ADORA1 ADORA1 APLNR APLNR HCAR2 HCAR2 TAS2R16 TAS2R16 CASR CASR LPAR5 LPAR5 A0A287ACS9_PIG A0A287ACS9_PIG LOC110255211 LOC110255211 TAS1R2 TAS1R2 RGS8 RGS8 PDE4A PDE4A GNA14 GNA14 RGS9 RGS9 GRM7 GRM7 CXCL9 CXCL9 PDE4D PDE4D RGS13 RGS13 LPAR1 LPAR1 ADCY8 ADCY8 GNB1 GNB1 GAL GAL TAS2R10 TAS2R10 RGS19 RGS19 ADCY9 ADCY9 SST SST CHRM2 CHRM2 P2RY14 P2RY14 PRKCD PRKCD PNOC PNOC PPP2R5D PPP2R5D GPR17 GPR17 PDE4C PDE4C ADCY4 ADCY4 NPB NPB ADCY3 ADCY3 CXCR4 CXCR4 PLA2G4A PLA2G4A PRKAR1B PRKAR1B CCL16 CCL16 GNAT1 GNAT1 PLCB2 PLCB2 CCR10 CCR10 GPSM1 GPSM1 CNR2 CNR2 GABBR2 GABBR2 GPSM3 GPSM3 PDE1A PDE1A RGS16 RGS16 RGS3 RGS3 GPR183 GPR183 S1PR5 S1PR5 PLCB1 PLCB1 ADORA3 ADORA3 CXCL12 CXCL12 CCL4 CCL4 S1PR2 S1PR2 PDE1B PDE1B CCL25 CCL25 CNR1 CNR1 LOC100621431 LOC100621431 GABBR1 GABBR1 PCP2 PCP2 NMUR1 NMUR1 GALR1 GALR1 APLN APLN PPBP PPBP GNG10 GNG10 RGS5 RGS5 GPR37 GPR37 NPW NPW GRK2 GRK2 PPP2CB PPP2CB CCR5 CCR5 SSTR3 SSTR3 MAPK1 MAPK1 CXCL11 CXCL11 PDE4B PDE4B RGS6 RGS6 RGR RGR PPYR1 PPYR1 ADRA2A ADRA2A CCL19 CCL19 CCL27 CCL27 CXCR6 CXCR6 CCR1 CCR1 GNAI2 GNAI2 GRM2 GRM2 RHO RHO P2RY12 P2RY12 DRD3 DRD3 P2RY4 P2RY4 AGTR2 AGTR2 DRD4 DRD4 PLCB3 PLCB3 PTGDR2 PTGDR2 CHRM4 CHRM4 GNA15 GNA15 S1PR4 S1PR4 RLN3 RLN3 GRM6 GRM6 RGS14 RGS14 PPP2CA PPP2CA MTNR1B MTNR1B CXCR5 CXCR5 GNGT1 GNGT1 GRM3 GRM3 GNAT3 GNAT3 GNAI1 GNAI1 F1SS05_PIG F1SS05_PIG CXCR2 CXCR2 TAS2R41 TAS2R41 GALR3 GALR3 ADCY6 ADCY6 TAS2R9 TAS2R9 GNB3 GNB3 PMCH PMCH GRM4 GRM4 SSTR1 SSTR1 PRKCG PRKCG TAS1R3 TAS1R3 TAS1R1 TAS1R1 CORT CORT LPAR3 LPAR3 RGS17 RGS17 MCHR2 MCHR2 PENK PENK RGS20 RGS20 OPRK1 OPRK1 RGS4 RGS4 RXFP4 RXFP4 GNAT2 GNAT2 GNAI3 GNAI3 GNB2 GNB2 GNG13 GNG13 ADRA2B ADRA2B RGS12 RGS12 NPY5R NPY5R CXCL8 CXCL8 AMCF-II AMCF-II RRH RRH S1PR3 S1PR3 HCAR1 HCAR1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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ACKR3Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (362 aa)
TAS2R60Taste receptor type 2. (314 aa)
OPN1SWG_PROTEIN_RECEP_F1_2 domain-containing protein. (351 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1136 aa)
CCL28C-C motif chemokine. (176 aa)
NMUR2G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (410 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (956 aa)
SSTR2Somatostatin receptor type 2; Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 [...] (360 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (669 aa)
CCR7G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (477 aa)
CCL1C-C motif chemokine. (94 aa)
CDK5Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (361 aa)
HTR1F5-hydroxytryptamine receptor 1F isoform X1. (366 aa)
LOC494564Medium-wave-sensitive opsin. (364 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1259 aa)
GPSM2G-protein-signaling modulator 2 isoform X1. (680 aa)
CCR6C-C motif chemokine receptor 6; Belongs to the G-protein coupled receptor 1 family. (376 aa)
TAS2R39Taste 2 receptor member 39; Belongs to the G-protein coupled receptor T2R family. (375 aa)
TAS2R4Taste receptor type 2. (296 aa)
TAS2R3Taste receptor type 2. (316 aa)
ADRA2CAdrenoceptor alpha 2C. (460 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (248 aa)
CCR8C-C motif chemokine receptor 8; Belongs to the G-protein coupled receptor 1 family. (379 aa)
CCR2C-C chemokine receptor type 2 isoform B; Belongs to the G-protein coupled receptor 1 family. (373 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
SUCNR1Succinate receptor 1; Belongs to the G-protein coupled receptor 1 family. (318 aa)
GNALG protein subunit alpha L. (419 aa)
GPER1G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (360 aa)
GALR2Galanin receptor type 2; Belongs to the G-protein coupled receptor 1 family. (343 aa)
OPN5Opsin 5; Belongs to the G-protein coupled receptor 1 family. (378 aa)
C5AR1C5a anaphylatoxin chemotactic receptor 1; Belongs to the G-protein coupled receptor 1 family. (351 aa)
CXCR3C-X-C chemokine receptor type 3 isoform 1; Belongs to the G-protein coupled receptor 1 family. (361 aa)
AGTAngiotensinogen; Belongs to the serpin family. (482 aa)
SRCTyrosine-protein kinase. (559 aa)
CCL20C-C motif chemokine. (153 aa)
RGS11Regulator of G protein signaling 11. (463 aa)
GNB5G protein subunit beta 5. (420 aa)
RGS1Regulator of G-protein signaling 1. (209 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (339 aa)
CXCL10C-X-C motif chemokine. (104 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (240 aa)
PRKAR2BProtein kinase cAMP-dependent type II regulatory subunit beta. (468 aa)
RGS21Regulator of G protein signaling 21. (152 aa)
CCR4C-C chemokine receptor type 4 isoform X1; Belongs to the G-protein coupled receptor 1 family. (360 aa)
SSTR5G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (305 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1079 aa)
RGS18Regulator of G-protein signaling 18. (235 aa)
TAS2R7Taste receptor type 2. (312 aa)
GNAQGuanine nucleotide-binding protein G(q) subunit alpha; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. (359 aa)
GPR18N-arachidonyl glycine receptor; Belongs to the G-protein coupled receptor 1 family. (331 aa)
GPR37L1G protein-coupled receptor 37 like 1. (459 aa)
LPAR2Lysophosphatidic acid receptor 2; Belongs to the G-protein coupled receptor 1 family. (351 aa)
CCL21Putative CCL21 chemokine. (134 aa)
RXFP3G_PROTEIN_RECEP_F1_2 domain-containing protein. (458 aa)
CCR9Chemokine (C-C motif) receptor 9 isoform A; Belongs to the G-protein coupled receptor 1 family. (369 aa)
GNB4G protein subunit beta 4. (340 aa)
P2RY13Purinergic receptor P2Y13; Belongs to the G-protein coupled receptor 1 family. (333 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
LOC100154902Taste receptor type 2. (350 aa)
GPR55G-protein coupled receptor 55; Belongs to the G-protein coupled receptor 1 family. (361 aa)
RGS7Regulator of G-protein signaling 7 isoform 3. (500 aa)
NPBWR2Neuropeptides B and W receptor 2; Belongs to the G-protein coupled receptor 1 family. (298 aa)
CXCL13C-X-C motif chemokine. (111 aa)
ADORA1Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (326 aa)
APLNRApelin receptor; Belongs to the G-protein coupled receptor 1 family. (383 aa)
HCAR2Hydroxycarboxylic acid receptor 2; Belongs to the G-protein coupled receptor 1 family. (363 aa)
TAS2R16Taste receptor type 2. (300 aa)
CASRExtracellular calcium-sensing receptor; G-protein-coupled receptor that senses changes in the extracellular concentration of calcium ions and plays a key role in maintaining calcium homeostasis. Senses fluctuations in the circulating calcium concentration and modulates the production of parathyroid hormone (PTH) in parathyroid glands (By similarity). The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system. The G-protein- coupled receptor activity is activated by a co-agonist mechanism: aromatic amino acids, such as [...] (1089 aa)
LPAR5Lysophosphatidic acid receptor 5; Belongs to the G-protein coupled receptor 1 family. (367 aa)
A0A287ACS9_PIGGuanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (65 aa)
LOC110255211Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (125 aa)
TAS1R2Taste 1 receptor member 2. (836 aa)
RGS8Regulator of G protein signaling 8. (236 aa)
PDE4APhosphodiesterase. (894 aa)
GNA14Guanine nucleotide-binding protein alpha 14. (355 aa)
RGS9Regulator of G-protein signaling 9 isoform 2. (673 aa)
GRM7Metabotropic glutamate receptor 7 isoform X1. (921 aa)
CXCL9C-X-C motif chemokine. (126 aa)
PDE4DPhosphodiesterase. (809 aa)
RGS13Regulator of G protein signaling 13. (182 aa)
LPAR1Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (364 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1250 aa)
GNB1G protein subunit beta 1. (395 aa)
GALGalanin message-associated peptide; Endocrine hormone of the central and peripheral nervous systems that binds and activates the G protein-coupled receptors GALR1, GALR2, and GALR3. This small neuropeptide may regulate diverse physiologic functions including contraction of smooth muscle of the gastrointestinal and genitourinary tract, growth hormone and insulin release and adrenal secretion; Belongs to the galanin family. (337 aa)
TAS2R10Taste receptor type 2. (309 aa)
RGS19Regulator of G protein signaling 19. (302 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1379 aa)
SSTSomatostatin-14; [Somatostatin-14]: Inhibits the secretion of pituitary hormones, including that of growth hormone/somatotropin (GH1), PRL, ACTH, luteinizing hormone (LH) and TSH. Also impairs ghrelin- and GnRH- stimulated secretion of GH1 and LH; the inhibition of ghrelin- stimulated secretion of GH1 can be further increased by neuronostatin. (116 aa)
CHRM2Muscarinic acetylcholine receptor M2; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is adenylate cyclase inhibition; Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHRM2 sub-subfamily. (466 aa)
P2RY14Purinergic receptor P2Y14. (338 aa)
PRKCDProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (723 aa)
PNOCNociceptin. (203 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (614 aa)
GPR17G protein-coupled receptor 17; Belongs to the G-protein coupled receptor 1 family. (339 aa)
PDE4CPhosphodiesterase. (729 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1102 aa)
NPBUncharacterized protein. (176 aa)
ADCY3Adenylate cyclase 3. (1320 aa)
CXCR4C-X-C chemokine receptor type 4; Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Involved in the AKT signaling cascade (By similarity). Plays a role in regulation of cell migration, e.g. during wound healing. Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Binds bacterial lipopolysaccharide (LPS) et mediates LPS- induced inflammatory response, including TNF secretion by monocytes (By similarity). Inv [...] (353 aa)
PLA2G4APhospholipase A2. (758 aa)
PRKAR1BProtein kinase cAMP-dependent type I regulatory subunit beta. (454 aa)
CCL16C-C motif chemokine. (120 aa)
GNAT1Guanine nucleotide-binding protein G(T) subunit alpha-1 isoform X2. (350 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1194 aa)
CCR10G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (375 aa)
GPSM1G protein signaling modulator 1. (707 aa)
CNR2Cannabinoid receptor 2 isoform X1; Belongs to the G-protein coupled receptor 1 family. (360 aa)
GABBR2Gamma-aminobutyric acid type B receptor subunit 2. (958 aa)
GPSM3G protein signaling modulator 3. (219 aa)
PDE1APhosphodiesterase. (545 aa)
RGS16Regulator of G-protein signaling 16; Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP- bound form. Plays an important role in the phototransduction cascade by regulating the lifetime and effective concentration of activated transducin alpha. May regulate extra and intracellular mitogenic signals. (274 aa)
RGS3Regulator of G protein signaling 3. (913 aa)
GPR183G-protein coupled receptor 183 isoform X1; Belongs to the G-protein coupled receptor 1 family. (356 aa)
S1PR5Sphingosine 1-phosphate receptor 5; Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. Is coupled to both the G(i/O)alpha and G(12) subclass of heteromeric G-proteins (By similarity). (463 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1173 aa)
ADORA3G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (348 aa)
CXCL12C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (119 aa)
CCL4C-C motif chemokine 4; Monokine with inflammatory and chemokinetic properties. (96 aa)
S1PR2Sphingosine 1-phosphate receptor 2. (351 aa)
PDE1BPhosphodiesterase. (535 aa)
CCL25C-C motif chemokine 25; Potentially involved in T-cell development. Recombinant protein shows chemotactic activity on thymocytes, macrophages, THP-1 cells, and dendritics cells but is inactive on peripheral blood lymphocytes and neutrophils. Binds to CCR9. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4 (By similarity); Belongs to the intercrine beta (chemokine CC) family. (220 aa)
CNR1Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] (472 aa)
LOC100621431Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (234 aa)
GABBR1Gamma-aminobutyric acid type B receptor subunit 1. (1247 aa)
PCP2Purkinje cell protein 2. (224 aa)
NMUR1Neuromedin U receptor 1; Belongs to the G-protein coupled receptor 1 family. (556 aa)
GALR1Galanin receptor 1; Belongs to the G-protein coupled receptor 1 family. (349 aa)
APLNApelin. (77 aa)
PPBPPlatelet basic protein; Chemoattractant factor for neutrophils. (159 aa)
GNG10Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
RGS5Regulator of G-protein signaling 5; Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i)-alpha and G(o)-alpha, but not to G(s)-alpha (By similarity). (206 aa)
GPR37G protein-coupled receptor 37. (614 aa)
NPWNeuropeptide W-23; Plays a regulatory role in the organization of neuroendocrine signals accessing the anterior pituitary gland. Stimulates water drinking and food intake. May play a role in the hypothalamic response to stress (By similarity); Belongs to the neuropeptide B/W family. (152 aa)
GRK2G protein-coupled receptor kinase 2. (778 aa)
PPP2CBSerine/threonine-protein phosphatase. (476 aa)
CCR5C-C motif chemokine receptor 5 (gene/pseudogene); Belongs to the G-protein coupled receptor 1 family. (361 aa)
SSTR3Somatostatin receptor 3; Belongs to the G-protein coupled receptor 1 family. (421 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (568 aa)
CXCL11C-X-C motif chemokine. (129 aa)
PDE4BPhosphodiesterase. (736 aa)
RGS6Regulator of G protein signaling 6. (516 aa)
RGRRetinal G protein coupled receptor; Belongs to the G-protein coupled receptor 1 family. Opsin subfamily. (310 aa)
PPYR1Neuropeptide Y-family receptor Y4; Belongs to the G-protein coupled receptor 1 family. (375 aa)
ADRA2AAlpha-2A adrenergic receptor; Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins. (465 aa)
CCL19C-C motif chemokine. (100 aa)
CCL27C-C motif chemokine 27. (107 aa)
CXCR6Chemokine (C-X-C motif) receptor 6; Belongs to the G-protein coupled receptor 1 family. (341 aa)
CCR1Chemokine (C-C motif) receptor 1; Belongs to the G-protein coupled receptor 1 family. (354 aa)
GNAI2G protein subunit alpha i2. (355 aa)
GRM2Glutamate metabotropic receptor 2. (872 aa)
RHORhodopsin; Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G-proteins. Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by the arrestin SAG and terminates signaling (By similarity). (348 aa)
P2RY12Purinergic receptor P2Y12. (339 aa)
DRD3Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (447 aa)
P2RY4G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (365 aa)
AGTR2Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family. (362 aa)
DRD4Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family. (333 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1233 aa)
PTGDR2Prostaglandin D2 receptor 2; Belongs to the G-protein coupled receptor 1 family. (464 aa)
CHRM4Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (479 aa)
GNA15Guanine nucleotide-binding protein subunit alpha-15. (374 aa)
S1PR4Sphingosine 1-phosphate receptor 4. (437 aa)
RLN3Relaxin-3 A chain; May play a role in neuropeptide signaling processes. Ligand for LGR7, relaxin-3 receptor-1 and relaxin-3 receptor-2 (By similarity). (140 aa)
GRM6Glutamate metabotropic receptor 6. (872 aa)
RGS14Regulator of G protein signaling 14. (567 aa)
PPP2CASerine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGO2 to protect centromeric cohesin from separase- mediated cleavage in oocytes specifically during meiosis I. Activates RAF1 by dephosphorylating it at 'Ser-259' (By similarity). (309 aa)
MTNR1BMelatonin receptor 1B; Belongs to the G-protein coupled receptor 1 family. (364 aa)
CXCR5C-X-C chemokine receptor type 5 isoform 1; Belongs to the G-protein coupled receptor 1 family. (373 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (89 aa)
GRM3Glutamate metabotropic receptor 3. (879 aa)
GNAT3G protein subunit alpha transducin 3. (354 aa)
GNAI1Guanine nucleotide-binding protein G(I) subunit alpha-1 isoform 1. (354 aa)
F1SS05_PIGG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (343 aa)
CXCR2G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (382 aa)
TAS2R41Taste receptor type 2. (307 aa)
GALR3Galanin receptor 3; Belongs to the G-protein coupled receptor 1 family. (376 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1164 aa)
TAS2R9Taste receptor type 2. (311 aa)
GNB3Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 isoform 1. (340 aa)
PMCHPro-MCH preproprotein. (165 aa)
GRM4Glutamate metabotropic receptor 4. (966 aa)
SSTR1Somatostatin receptor 1; Belongs to the G-protein coupled receptor 1 family. (354 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (759 aa)
TAS1R3G_PROTEIN_RECEP_F3_4 domain-containing protein. (855 aa)
TAS1R1Taste 1 receptor member 1. (844 aa)
CORTSomatostatin domain-containing protein. (108 aa)
LPAR3Lysophosphatidic acid receptor 3 isoform X1; Belongs to the G-protein coupled receptor 1 family. (354 aa)
RGS17Regulator of G-protein signaling 17. (210 aa)
MCHR2G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (339 aa)
PENKProenkephalin. (274 aa)
RGS20Regulator of G protein signaling 20. (374 aa)
OPRK1Opioid receptor kappa 1; Belongs to the G-protein coupled receptor 1 family. (380 aa)
RGS4Regulator of G protein signaling 4. (205 aa)
RXFP4Relaxin-3/INSL7 receptor 2. (373 aa)
GNAT2G protein subunit alpha transducin 2. (354 aa)
GNAI3Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
GNB2G protein subunit beta 2. (340 aa)
GNG13G protein subunit gamma 13. (67 aa)
ADRA2BAlpha-2B adrenergic receptor. (446 aa)
RGS12Regulator of G protein signaling 12. (1441 aa)
NPY5RNeuropeptide Y receptor type 5; Receptor for neuropeptide Y and peptide YY. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Seems to be associated with food intake. Could be involved in feeding disorders (By similarity); Belongs to the G-protein coupled receptor 1 family. (446 aa)
CXCL8Interleukin-8; IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus; Belongs to the intercrine alpha (chemokine CxC) family. (103 aa)
AMCF-IIAlveolar macrophage chemotactic factor 2; Has chemotactic activity for porcine, and in a lesser extent, for human neutrophils; Belongs to the intercrine alpha (chemokine CxC) family. (117 aa)
RRHRetinal pigment epithelium-derived rhodopsin homolog; Belongs to the G-protein coupled receptor 1 family. (336 aa)
S1PR3Sphingosine-1-phosphate receptor 3; Belongs to the G-protein coupled receptor 1 family. (377 aa)
HCAR1Hydroxycarboxylic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (340 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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