STRINGSTRING
HIST1H2BD HIST1H2BD LOC100152135 LOC100152135 LOC100152878 LOC100152878 H2AC20 H2AC20 LOC102159655 LOC102159655 H2AFZ H2AFZ LOC100155267 LOC100155267 SIRT1 SIRT1 LOC100521680 LOC100521680 I3LAJ9_PIG I3LAJ9_PIG LOC100158121 LOC100158121 RRP8 RRP8 LOC100621389 LOC100621389 A0A286ZRB3_PIG A0A286ZRB3_PIG H2BC11 H2BC11 H2AJ H2AJ H2BU1 H2BU1 SUV39H1 SUV39H1 H2AC6 H2AC6 HIST1H3E HIST1H3E LOC100620620 LOC100620620 H2BC21 H2BC21 H2AX H2AX H2AZ2 H2AZ2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HIST1H2BDHistone H2B; Belongs to the histone H2B family. (126 aa)
LOC100152135Histone H2B; Belongs to the histone H2B family. (127 aa)
LOC100152878Histone H2B; Belongs to the histone H2B family. (127 aa)
H2AC20Histone H2A; Belongs to the histone H2A family. (129 aa)
LOC102159655Histone H2A; Belongs to the histone H2A family. (130 aa)
H2AFZHistone H2A; Belongs to the histone H2A family. (128 aa)
LOC100155267Histone domain-containing protein; Belongs to the histone H2B family. (126 aa)
SIRT1NAD-dependent protein deacetylase sirtuin-1 isoform a. (742 aa)
LOC100521680Histone H3.3; Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in [...] (136 aa)
I3LAJ9_PIGHistone H2B; Belongs to the histone H2B family. (168 aa)
LOC100158121Histone H2A; Belongs to the histone H2A family. (130 aa)
RRP8Ribosomal RNA-processing protein 8; Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone- modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and pr [...] (593 aa)
LOC100621389Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
A0A286ZRB3_PIGHistone domain-containing protein. (130 aa)
H2BC11Histone H2B; Belongs to the histone H2B family. (149 aa)
H2AJHistone H2A; Belongs to the histone H2A family. (129 aa)
H2BU1Histone H2B; Belongs to the histone H2B family. (126 aa)
SUV39H1Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (462 aa)
H2AC6Histone H2A; Belongs to the histone H2A family. (145 aa)
HIST1H3EHistone H3; Belongs to the histone H3 family. (136 aa)
LOC100620620Histone H2A; Belongs to the histone H2A family. (113 aa)
H2BC21Histone H2B; Belongs to the histone H2B family. (126 aa)
H2AXHistone H2A; Belongs to the histone H2A family. (143 aa)
H2AZ2Histone H2A; Belongs to the histone H2A family. (145 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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