46 items (Sus scrofa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TBC1D8B	TBC1 domain family member 8B. (1101 aa)
	BLOC1S1	Uncharacterized protein. (125 aa)
	IGF2R	Insulin-like growth factor II receptor. (2488 aa)
	SH3GL2	SH3 domain containing GRB2 like 2, endophilin A1. (352 aa)
	AP4B1	AP complex subunit beta; Belongs to the adaptor complexes large subunit family. (737 aa)
	SNX5	Sorting nexin; Involved in several stages of intracellular trafficking. (404 aa)
	HIP1R	Huntingtin-interacting protein 1-related protein isoform 1. (1068 aa)
	AP1B1	AP complex subunit beta. (949 aa)
	GOLGB1	Golgin B1. (3270 aa)
	AP3B1	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1130 aa)
	PICALM	Phosphatidylinositol binding clathrin assembly protein. (700 aa)
	CPD	Carboxypeptidase D. (1374 aa)
	BLOC1S4	Biogenesis of lysosomal organelles complex 1 subunit 4. (211 aa)
	AP1M2	AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. (497 aa)
	VAMP8	V-SNARE coiled-coil homology domain-containing protein. (143 aa)
	PIK3C2A	Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family. (1669 aa)
	AP4E1	Adaptor related protein complex 4 subunit epsilon 1. (1160 aa)
	ACBD3	Uncharacterized protein. (528 aa)
	GAK	Cyclin G associated kinase. (1233 aa)
	YIPF6	Protein YIPF. (235 aa)
	TFRC	Transferrin receptor protein 1; Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). Positively regulates T and B cell proliferation through iron uptake (By similarity). (794 aa)
	ARRB1	Arrestin beta 1. (607 aa)
	DTNBP1	Uncharacterized protein. (373 aa)
	SNAPIN	SNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] (136 aa)
	ARF1	ADP ribosylation factor 1; Belongs to the small GTPase superfamily. Arf family. (211 aa)
	SORT1	Sortilin. (963 aa)
	CLTA	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (242 aa)
	AP1S3	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (154 aa)
	AP1M1	AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. (483 aa)
	TXNDC5	Thioredoxin domain containing 5. (431 aa)
	DNM2	Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (877 aa)
	AP1S2	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (163 aa)
	SNX2	Sorting nexin-2 isoform 1. (525 aa)
	AP3S1	Clat_adaptor_s domain-containing protein. (219 aa)
	A0A5G2QCF0_PIG	Uncharacterized protein. (396 aa)
	NAPA	NSF attachment protein alpha. (299 aa)
	NECAP1	NECAP endocytosis associated 1. (274 aa)
	CLTC	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1702 aa)
	AP1S1	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (163 aa)
	OCRL	OCRL inositol polyphosphate-5-phosphatase. (903 aa)
	TPD52	Uncharacterized protein. (247 aa)
	AP1G1	AP-1 complex subunit gamma. (825 aa)
	SNX9	Sorting nexin 9. (632 aa)
	VAMP2	V-SNARE coiled-coil homology domain-containing protein. (189 aa)
	BLOC1S6	Biogenesis of lysosome-related organelles complex 1 subunit 6; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particular [...] (161 aa)
	TPD52L1	TPD52 like 1. (228 aa)

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A5G2QCF0_PIG	AP1B1	ENSSSCP00000059704	ENSSSCP00000010649	Uncharacterized protein.	AP complex subunit beta.	0.837
A0A5G2QCF0_PIG	AP1G1	ENSSSCP00000059704	ENSSSCP00000069075	Uncharacterized protein.	AP-1 complex subunit gamma.	0.551
A0A5G2QCF0_PIG	AP1M1	ENSSSCP00000059704	ENSSSCP00000040246	Uncharacterized protein.	AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.	0.630
A0A5G2QCF0_PIG	AP1M2	ENSSSCP00000059704	ENSSSCP00000022386	Uncharacterized protein.	AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.	0.630
A0A5G2QCF0_PIG	AP1S1	ENSSSCP00000059704	ENSSSCP00000067925	Uncharacterized protein.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.511
A0A5G2QCF0_PIG	AP1S2	ENSSSCP00000059704	ENSSSCP00000053766	Uncharacterized protein.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.511
A0A5G2QCF0_PIG	AP1S3	ENSSSCP00000059704	ENSSSCP00000039439	Uncharacterized protein.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.511
A0A5G2QCF0_PIG	AP3B1	ENSSSCP00000059704	ENSSSCP00000014994	Uncharacterized protein.	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family.	0.549
A0A5G2QCF0_PIG	AP3S1	ENSSSCP00000059704	ENSSSCP00000058249	Uncharacterized protein.	Clat_adaptor_s domain-containing protein.	0.521
A0A5G2QCF0_PIG	AP4B1	ENSSSCP00000059704	ENSSSCP00000007213	Uncharacterized protein.	AP complex subunit beta; Belongs to the adaptor complexes large subunit family.	0.598
A0A5G2QCF0_PIG	AP4E1	ENSSSCP00000059704	ENSSSCP00000025160	Uncharacterized protein.	Adaptor related protein complex 4 subunit epsilon 1.	0.541
A0A5G2QCF0_PIG	ARF1	ENSSSCP00000059704	ENSSSCP00000036916	Uncharacterized protein.	ADP ribosylation factor 1; Belongs to the small GTPase superfamily. Arf family.	0.549
A0A5G2QCF0_PIG	ARRB1	ENSSSCP00000059704	ENSSSCP00000033134	Uncharacterized protein.	Arrestin beta 1.	0.522
A0A5G2QCF0_PIG	CLTA	ENSSSCP00000059704	ENSSSCP00000039273	Uncharacterized protein.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.513
A0A5G2QCF0_PIG	CLTC	ENSSSCP00000059704	ENSSSCP00000065629	Uncharacterized protein.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.553
A0A5G2QCF0_PIG	CPD	ENSSSCP00000059704	ENSSSCP00000018857	Uncharacterized protein.	Carboxypeptidase D.	0.558
A0A5G2QCF0_PIG	DNM2	ENSSSCP00000059704	ENSSSCP00000052945	Uncharacterized protein.	Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.523
A0A5G2QCF0_PIG	IGF2R	ENSSSCP00000059704	ENSSSCP00000004370	Uncharacterized protein.	Insulin-like growth factor II receptor.	0.582
A0A5G2QCF0_PIG	NAPA	ENSSSCP00000059704	ENSSSCP00000059962	Uncharacterized protein.	NSF attachment protein alpha.	0.506
A0A5G2QCF0_PIG	PICALM	ENSSSCP00000059704	ENSSSCP00000015834	Uncharacterized protein.	Phosphatidylinositol binding clathrin assembly protein.	0.499