(9 nodes) Repression of WNT target genes network (Sus scrofa)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TLE3	TLE family member 3, transcriptional corepressor. (808 aa)
	TCF7L2	Transcription factor 7 like 2. (669 aa)
	CTBP2	C-terminal binding protein 2. (982 aa)
	TCF7	Transcription factor 7. (484 aa)
	TLE4	TLE family member 4, transcriptional corepressor. (774 aa)
	LEF1	Lymphoid enhancer binding factor 1. (429 aa)
	CTBP1	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (428 aa)
	TLE1	TLE family member 1, transcriptional corepressor. (770 aa)
	TCF7L1	HMG box domain-containing protein. (412 aa)

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CTBP1	CTBP2	ENSSSCP00000039126	ENSSSCP00000011449	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	C-terminal binding protein 2.	0.935
CTBP1	LEF1	ENSSSCP00000039126	ENSSSCP00000033976	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Lymphoid enhancer binding factor 1.	0.933
CTBP1	TCF7	ENSSSCP00000039126	ENSSSCP00000027825	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Transcription factor 7.	0.952
CTBP1	TCF7L1	ENSSSCP00000039126	ENSSSCP00000059978	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	HMG box domain-containing protein.	0.767
CTBP1	TCF7L2	ENSSSCP00000039126	ENSSSCP00000011333	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Transcription factor 7 like 2.	0.602
CTBP1	TLE1	ENSSSCP00000039126	ENSSSCP00000045163	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	TLE family member 1, transcriptional corepressor.	0.541
CTBP1	TLE3	ENSSSCP00000039126	ENSSSCP00000005346	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	TLE family member 3, transcriptional corepressor.	0.541
CTBP1	TLE4	ENSSSCP00000039126	ENSSSCP00000033643	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	TLE family member 4, transcriptional corepressor.	0.541
CTBP2	CTBP1	ENSSSCP00000011449	ENSSSCP00000039126	C-terminal binding protein 2.	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.935
CTBP2	LEF1	ENSSSCP00000011449	ENSSSCP00000033976	C-terminal binding protein 2.	Lymphoid enhancer binding factor 1.	0.935
CTBP2	TCF7	ENSSSCP00000011449	ENSSSCP00000027825	C-terminal binding protein 2.	Transcription factor 7.	0.930
CTBP2	TCF7L1	ENSSSCP00000011449	ENSSSCP00000059978	C-terminal binding protein 2.	HMG box domain-containing protein.	0.707
CTBP2	TCF7L2	ENSSSCP00000011449	ENSSSCP00000011333	C-terminal binding protein 2.	Transcription factor 7 like 2.	0.602
CTBP2	TLE4	ENSSSCP00000011449	ENSSSCP00000033643	C-terminal binding protein 2.	TLE family member 4, transcriptional corepressor.	0.465
LEF1	CTBP1	ENSSSCP00000033976	ENSSSCP00000039126	Lymphoid enhancer binding factor 1.	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.933
LEF1	CTBP2	ENSSSCP00000033976	ENSSSCP00000011449	Lymphoid enhancer binding factor 1.	C-terminal binding protein 2.	0.935
LEF1	TCF7	ENSSSCP00000033976	ENSSSCP00000027825	Lymphoid enhancer binding factor 1.	Transcription factor 7.	0.939
LEF1	TCF7L1	ENSSSCP00000033976	ENSSSCP00000059978	Lymphoid enhancer binding factor 1.	HMG box domain-containing protein.	0.636
LEF1	TCF7L2	ENSSSCP00000033976	ENSSSCP00000011333	Lymphoid enhancer binding factor 1.	Transcription factor 7 like 2.	0.645
LEF1	TLE1	ENSSSCP00000033976	ENSSSCP00000045163	Lymphoid enhancer binding factor 1.	TLE family member 1, transcriptional corepressor.	0.716