STRINGSTRING
DLAT DLAT ALDH8A1 ALDH8A1 RDH5 RDH5 PPARD PPARD RDH11 RDH11 DHRS3 DHRS3 CRABP2 CRABP2 CYP26B1 CYP26B1 RDH14 RDH14 ADH4 ADH4 CYP26C1 CYP26C1 CYP26A1 CYP26A1 CPT1A CPT1A CRABP1 CRABP1 ALDH1A1 ALDH1A1 RARG RARG DHRS4 DHRS4 RDH10 RDH10 RARA RARA ALDH1A2 ALDH1A2 RDH13 RDH13 FABP5 FABP5 RDH16 RDH16 AKR1C1 AKR1C1 PDK3 PDK3 DHRS9 DHRS9 RXRG RXRG PDK2 PDK2 ADH1C ADH1C SDR16C5 SDR16C5 PDHB PDHB PDK1 PDK1 ALDH1A3 ALDH1A3 PDK4 PDK4 PDHX PDHX RXRA RXRA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DLATAcetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (667 aa)
ALDH8A1Aldehyde dehydrogenase 8 family member A1; Belongs to the aldehyde dehydrogenase family. (521 aa)
RDH5Retinol dehydrogenase 5; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (429 aa)
PPARDPeroxisome proliferator-activated receptor delta. (441 aa)
RDH11Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (306 aa)
DHRS3Short-chain dehydrogenase/reductase 3 isoform 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (302 aa)
CRABP2FABP domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (138 aa)
CYP26B1Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. (512 aa)
RDH14Retinol dehydrogenase 14; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (336 aa)
ADH4Alcohol dehydrogenase 4 isoform 2. (380 aa)
CYP26C1Cytochrome P450 family 26 subfamily C member 1; Belongs to the cytochrome P450 family. (522 aa)
CYP26A1Cytochrome P450 family 26 subfamily A member 1; Belongs to the cytochrome P450 family. (497 aa)
CPT1AUncharacterized protein; Belongs to the carnitine/choline acetyltransferase family. (771 aa)
CRABP1Cellular retinoic acid-binding protein 1; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (137 aa)
ALDH1A1Aldehyde dehydrogenase 1 family member A1; Belongs to the aldehyde dehydrogenase family. (501 aa)
RARGRetinoic acid receptor gamma. (554 aa)
DHRS4Dehydrogenase/reductase SDR family member 4; Reduces all-trans-retinal and 9-cis retinal. Can also catalyze the oxidation of all-trans-retinol with NADP as co-factor, but with much lower efficiency. Reduces alkyl phenyl ketones and alpha- dicarbonyl compounds with aromatic rings, such as pyrimidine-4- aldehyde, 3-benzoylpyridine, 4-benzoylpyridine, menadione and 4- hexanoylpyridine. Has no activity towards aliphatic aldehydes and ketones. (279 aa)
RDH10Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)
RARARetinoic acid receptor alpha isoform X1. (462 aa)
ALDH1A2Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family. (527 aa)
RDH13Retinol dehydrogenase 13 isoform X1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (334 aa)
FABP5FABP domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (235 aa)
RDH16Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (317 aa)
AKR1C1Aldo-keto reductase family 1 member C3 isoform 2. (324 aa)
PDK3Protein-serine/threonine kinase. (415 aa)
DHRS9Dehydrogenase/reductase 9; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (346 aa)
RXRGRetinoic acid receptor RXR-gamma; Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid (By similarity). (463 aa)
PDK2Protein-serine/threonine kinase. (437 aa)
ADH1CPKS_ER domain-containing protein. (388 aa)
SDR16C5Short chain dehydrogenase/reductase family 16C, member 5; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (309 aa)
PDHBPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (361 aa)
PDK1Protein-serine/threonine kinase. (454 aa)
ALDH1A3Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family. (512 aa)
PDK4Protein-serine/threonine kinase. (411 aa)
PDHXDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (498 aa)
RXRARetinoid X receptor alpha. (701 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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