STRINGSTRING
NCKAP1L NCKAP1L WASF1 WASF1 MAPK1 MAPK1 CYFIP2 CYFIP2 ABL1 ABL1 BAIAP2 BAIAP2 MAPK3 MAPK3 WASL WASL RAC1 RAC1 ARPC1A ARPC1A WASF3 WASF3 ARPC3 ARPC3 ABI1 ABI1 NCKIPSD NCKIPSD BRK1 BRK1 ARPC5 ARPC5 ACTR3 ACTR3 GRB2 GRB2 WASF2 WASF2 NCK1 NCK1 CDC42 CDC42 ARPC1B ARPC1B ACTB ACTB ARPC4 ARPC4 ACTR2 ACTR2 ARPC2 ARPC2 ABI2 ABI2 ACTG1 ACTG1 WIPF1 WIPF1 NCKAP1 NCKAP1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NCKAP1LNCK associated protein 1 like. (1128 aa)
WASF1WH2 domain-containing protein. (559 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (568 aa)
CYFIP2Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1278 aa)
ABL1Tyrosine-protein kinase. (1146 aa)
BAIAP2BAI1 associated protein 2. (575 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (361 aa)
WASLWASP like actin nucleation promoting factor. (511 aa)
RAC1Rac family small GTPase 1. (186 aa)
ARPC1AActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (370 aa)
WASF3Wiskott-Aldrich syndrome protein family member 3 isoform X1. (498 aa)
ARPC3Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (178 aa)
ABI1Abl interactor 1 isoform b. (481 aa)
NCKIPSDNCK interacting protein with SH3 domain. (715 aa)
BRK1BRICK1 subunit of SCAR/WAVE actin nucleating complex. (103 aa)
ARPC5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (151 aa)
ACTR3Actin related protein 3; Belongs to the actin family. (422 aa)
GRB2Growth factor receptor-bound protein 2 isoform 1. (217 aa)
WASF2Wiskott-Aldrich syndrome protein family member 2 isoform 2. (498 aa)
NCK1Cytoplasmic protein. (377 aa)
CDC42Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] (197 aa)
ARPC1BActin related protein 2/3 complex subunit 1B. (440 aa)
ACTBActin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (375 aa)
ARPC4Actin related protein 2/3 complex subunit 4. (231 aa)
ACTR2Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (404 aa)
ARPC2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (273 aa)
ABI2Abl interactor 2. (542 aa)
ACTG1Actin gamma 1. (381 aa)
WIPF1WH2 domain-containing protein. (515 aa)
NCKAP1NCK associated protein 1. (1134 aa)
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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