11 items (Sus scrofa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TNFRSF13C	Tumor necrosis factor receptor superfamily member 13C. (186 aa)
	TNFSF12	TNF superfamily member 12; Belongs to the tumor necrosis factor family. (386 aa)
	CD40	Tumor necrosis factor receptor superfamily member 5; Receptor for TNFSF5/CD40LG (By similarity). Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion (By similarity). (278 aa)
	BIRC3	Baculoviral IAP repeat containing 3. (603 aa)
	TRAF2	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (520 aa)
	TNFSF11	TNF superfamily member 11; Belongs to the tumor necrosis factor family. (319 aa)
	TNFSF13B	Tumor necrosis factor superfamily member 13b; Belongs to the tumor necrosis factor family. (233 aa)
	MAP3K14	Mitogen-activated protein kinase kinase kinase 14. (930 aa)
	TNFRSF12A	Uncharacterized protein. (94 aa)
	TNFRSF11A	TNF receptor superfamily member 11a. (629 aa)
	TRAF3	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (572 aa)

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BIRC3	CD40	ENSSSCP00000049500	ENSSSCP00000052319	Baculoviral IAP repeat containing 3.	Tumor necrosis factor receptor superfamily member 5; Receptor for TNFSF5/CD40LG (By similarity). Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion (By similarity).	0.765
BIRC3	MAP3K14	ENSSSCP00000049500	ENSSSCP00000018362	Baculoviral IAP repeat containing 3.	Mitogen-activated protein kinase kinase kinase 14.	0.660
BIRC3	TNFRSF11A	ENSSSCP00000049500	ENSSSCP00000029324	Baculoviral IAP repeat containing 3.	TNF receptor superfamily member 11a.	0.566
BIRC3	TNFRSF12A	ENSSSCP00000049500	ENSSSCP00000020074	Baculoviral IAP repeat containing 3.	Uncharacterized protein.	0.568
BIRC3	TNFRSF13C	ENSSSCP00000049500	ENSSSCP00000044032	Baculoviral IAP repeat containing 3.	Tumor necrosis factor receptor superfamily member 13C.	0.574
BIRC3	TNFSF11	ENSSSCP00000049500	ENSSSCP00000010068	Baculoviral IAP repeat containing 3.	TNF superfamily member 11; Belongs to the tumor necrosis factor family.	0.525
BIRC3	TNFSF12	ENSSSCP00000049500	ENSSSCP00000048423	Baculoviral IAP repeat containing 3.	TNF superfamily member 12; Belongs to the tumor necrosis factor family.	0.592
BIRC3	TNFSF13B	ENSSSCP00000049500	ENSSSCP00000010188	Baculoviral IAP repeat containing 3.	Tumor necrosis factor superfamily member 13b; Belongs to the tumor necrosis factor family.	0.540
BIRC3	TRAF2	ENSSSCP00000049500	ENSSSCP00000006248	Baculoviral IAP repeat containing 3.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.982
BIRC3	TRAF3	ENSSSCP00000049500	ENSSSCP00000043474	Baculoviral IAP repeat containing 3.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.982
CD40	BIRC3	ENSSSCP00000052319	ENSSSCP00000049500	Tumor necrosis factor receptor superfamily member 5; Receptor for TNFSF5/CD40LG (By similarity). Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion (By similarity).	Baculoviral IAP repeat containing 3.	0.765
CD40	MAP3K14	ENSSSCP00000052319	ENSSSCP00000018362	Tumor necrosis factor receptor superfamily member 5; Receptor for TNFSF5/CD40LG (By similarity). Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion (By similarity).	Mitogen-activated protein kinase kinase kinase 14.	0.615
CD40	TNFRSF11A	ENSSSCP00000052319	ENSSSCP00000029324	Tumor necrosis factor receptor superfamily member 5; Receptor for TNFSF5/CD40LG (By similarity). Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion (By similarity).	TNF receptor superfamily member 11a.	0.580
CD40	TNFRSF12A	ENSSSCP00000052319	ENSSSCP00000020074	Tumor necrosis factor receptor superfamily member 5; Receptor for TNFSF5/CD40LG (By similarity). Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion (By similarity).	Uncharacterized protein.	0.563
CD40	TNFRSF13C	ENSSSCP00000052319	ENSSSCP00000044032	Tumor necrosis factor receptor superfamily member 5; Receptor for TNFSF5/CD40LG (By similarity). Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion (By similarity).	Tumor necrosis factor receptor superfamily member 13C.	0.724
CD40	TNFSF11	ENSSSCP00000052319	ENSSSCP00000010068	Tumor necrosis factor receptor superfamily member 5; Receptor for TNFSF5/CD40LG (By similarity). Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion (By similarity).	TNF superfamily member 11; Belongs to the tumor necrosis factor family.	0.803
CD40	TNFSF12	ENSSSCP00000052319	ENSSSCP00000048423	Tumor necrosis factor receptor superfamily member 5; Receptor for TNFSF5/CD40LG (By similarity). Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion (By similarity).	TNF superfamily member 12; Belongs to the tumor necrosis factor family.	0.552
CD40	TNFSF13B	ENSSSCP00000052319	ENSSSCP00000010188	Tumor necrosis factor receptor superfamily member 5; Receptor for TNFSF5/CD40LG (By similarity). Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion (By similarity).	Tumor necrosis factor superfamily member 13b; Belongs to the tumor necrosis factor family.	0.814
CD40	TRAF2	ENSSSCP00000052319	ENSSSCP00000006248	Tumor necrosis factor receptor superfamily member 5; Receptor for TNFSF5/CD40LG (By similarity). Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion (By similarity).	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.971
CD40	TRAF3	ENSSSCP00000052319	ENSSSCP00000043474	Tumor necrosis factor receptor superfamily member 5; Receptor for TNFSF5/CD40LG (By similarity). Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion (By similarity).	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.998