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| | WDR83 | WD repeat domain-containing protein 83. (311 aa) |
| | DNAJB1 | J domain-containing protein. (339 aa) |
| | RASAL3 | RAS protein activator like 3. (1012 aa) |
| | KXD1 | Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be in [...] (305 aa) |
| | PPP2CA | Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGO2 to protect centromeric cohesin from separase- mediated cleavage in oocytes specifically during meiosis I. Activates RAF1 by dephosphorylating it at 'Ser-259' (By similarity). (309 aa) |
| | PDGFRB | Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1181 aa) |
| | CAMK2A | Calcium/calmodulin-dependent protein kinase type II subunit alpha isoform 1; Belongs to the protein kinase superfamily. (489 aa) |
| | HGF | Hepatocyte growth factor; Belongs to the peptidase S1 family. (814 aa) |
| | PSMC2 | AAA domain-containing protein; Belongs to the AAA ATPase family. (433 aa) |
| | PPP2R5A | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (487 aa) |
| | ERBB4 | Receptor protein-tyrosine kinase. (1201 aa) |
| | FN1 | Fibronectin 1. (2462 aa) |
| | PSMD1 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (953 aa) |
| | MET | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] (1381 aa) |
| | FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa) |
| | GRB2 | Growth factor receptor-bound protein 2 isoform 1. (217 aa) |
| | ETV4 | ETS variant 4. (485 aa) |
| | PSMD3 | 26S proteasome non-ATPase regulatory subunit 3. (534 aa) |
| | ERBB2 | Receptor protein-tyrosine kinase. (1255 aa) |
| | PHB | Prohibitin. (272 aa) |
| | PSMD11 | Proteasome 26S subunit, non-ATPase 11. (421 aa) |
| | NF1 | Neurofibromin 1. (2847 aa) |
| | KSR1 | Kinase suppressor of ras 1. (928 aa) |
| | KLB | Klotho beta. (1044 aa) |
| | ABHD17B | Abhydrolase domain containing 17B. (292 aa) |
| | ERBB3 | Erb-b2 receptor tyrosine kinase 3. (1342 aa) |
| | CSF2 | Granulocyte-macrophage colony-stimulating factor; Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. (144 aa) |
| | FGF16 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa) |
| | RASA4B | Uncharacterized protein. (882 aa) |
| | KRAS | KRAS proto-oncogene, GTPase. (189 aa) |
| | IL2RB | Fibronectin type-III domain-containing protein. (783 aa) |
| | PSMF1 | Uncharacterized protein. (351 aa) |
| | FGG | Fibrinogen gamma chain. (454 aa) |
| | CSF2RB | Colony stimulating factor 2 receptor beta common subunit. (893 aa) |
| | RANBP9 | RAN binding protein 9. (732 aa) |
| | PSMB9 | Proteasome subunit beta. (219 aa) |
| | FRS3 | Fibroblast growth factor receptor substrate 3. (495 aa) |
| | RASGRF1 | Ras protein specific guanine nucleotide releasing factor 1. (1257 aa) |
| | IQGAP1 | IQ motif containing GTPase activating protein 1. (1709 aa) |
| | CSK | Tyrosine-protein kinase. (474 aa) |
| | PSME1 | Proteasome activator complex subunit 1; Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome (By similarity). (284 aa) |
| | PSMB11 | Proteasome subunit beta. (291 aa) |
| | PSMC1 | 26S proteasome regulatory subunit 4 isoform a; Belongs to the AAA ATPase family. (440 aa) |
| | PPP5C | Serine/threonine-protein phosphatase. (499 aa) |
| | GRIN2D | Glutamate ionotropic receptor NMDA type subunit 2D. (1332 aa) |
| | PSMA8 | Proteasome subunit alpha type. (250 aa) |
| | FOXO3 | Forkhead box protein O3 isoform X1. (672 aa) |
| | FYN | Tyrosine-protein kinase Fyn; Non-receptor tyrosine-protein kinase that plays a role in many biological processes including regulation of cell growth and survival, cell adhesion, integrin-mediated signaling, cytoskeletal remodeling, cell motility, immune response and axon guidance. Inactive FYN is phosphorylated on its C-terminal tail within the catalytic domain. Following activation by PKA, the protein subsequently associates with PTK2/FAK1, allowing PTK2/FAK1 phosphorylation, activation and targeting to focal adhesions. Involved in the regulation of cell adhesion and motility through [...] (537 aa) |
| | MAPK4 | Mitogen-activated protein kinase 4 isoform X1. (586 aa) |
| | SPTBN5 | Spectrin beta, non-erythrocytic 5. (3616 aa) |
| | RASGRP1 | RAS guanyl releasing protein 1. (797 aa) |
| | TEK | TEK receptor tyrosine kinase. (1147 aa) |
| | DAB2IP | DAB2 interacting protein. (1196 aa) |
| | PSMB7 | Proteasome subunit beta type-7; Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP- dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing pro [...] (277 aa) |
| | LAMTOR2 | Ragulator complex protein LAMTOR2 isoform 1. (125 aa) |
| | PSMD4 | Proteasome 26S subunit, non-ATPase 4. (380 aa) |
| | PSMA5 | Proteasome endopeptidase complex; Belongs to the peptidase T1A family. (232 aa) |
| | CDC14A | Cell division cycle 14A. (626 aa) |
| | FGF20 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa) |
| | NCOA3 | Uncharacterized protein. (1296 aa) |
| | PDGFA | Platelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (286 aa) |
| | SPRED2 | Sprouty-related, EVH1 domain-containing protein 2 isoform a. (417 aa) |
| | SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1369 aa) |
| | AREG | Amphiregulin long form. (247 aa) |
| | PAQR3 | Progestin and adipoQ receptor family member 3. (311 aa) |
| | KL | Klotho. (1011 aa) |
| | GFRA2 | GDNF family receptor alpha-2; Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor. (464 aa) |
| | FGF17 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (215 aa) |
| | PEBP1 | Uncharacterized protein. (187 aa) |
| | KSR2 | Kinase suppressor of ras 2. (950 aa) |
| | RASAL1 | RAS protein activator like 1. (784 aa) |
| | MAPKAPK5 | Protein kinase domain-containing protein. (543 aa) |
| | RET | Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1111 aa) |
| | VCL | Vinculin; Actin filament (F-actin)-binding protein involved in cell- matrix adhesion and cell-cell adhesion. Regulates cell-surface E- cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion; Belongs to the vinculin/alpha-catenin family. (1135 aa) |
| | DUSP10 | Dual specificity protein phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (482 aa) |
| | PRKCQ | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (732 aa) |
| | IL17RD | Interleukin-17 receptor D isoform a. (737 aa) |
| | PSMD6 | Proteasome 26S subunit, non-ATPase 6. (450 aa) |
| | IL5RA | Interleukin 5 receptor subunit alpha. (420 aa) |
| | PAK2 | Non-specific serine/threonine protein kinase. (524 aa) |
| | DLG3 | Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family. (849 aa) |
| | IL2RG | Cytokine receptor common subunit gamma. (395 aa) |
| | FGF4 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa) |
| | FGF3 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (232 aa) |
| | CDC42EP2 | Cdc42 effector protein 2; Probably involved in the organization of the actin cytoskeleton; Belongs to the BORG/CEP family. (214 aa) |
| | PPP2R5B | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (497 aa) |
| | ABHD17A | Alpha/beta hydrolase domain-containing protein 17A isoform 2. (310 aa) |
| | PSPN | Persephin. (153 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (766 aa) |
| | CNKSR1 | Connector enhancer of kinase suppressor of Ras 1. (648 aa) |
| | GOLGA7 | Golgin A7. (236 aa) |
| | FGF18 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (251 aa) |
| | FLT3 | Receptor-type tyrosine-protein kinase FLT3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (990 aa) |
| | ABHD17C | Abhydrolase domain containing 17C. (330 aa) |
| | SHC1 | SHC adaptor protein 1. (583 aa) |
| | RASGRP4 | RAS guanyl releasing protein 4. (673 aa) |
| | JAK2 | Tyrosine-protein kinase JAK2; Non-receptor tyrosine kinase involved in various processes such as cell growth, development, differentiation or histone modifications. Mediates essential signaling events in both innate and adaptive immunity. In the cytoplasm, plays a pivotal role in signal transduction via its association with type I receptors such as growth hormone (GHR), prolactin (PRLR), leptin (LEPR), erythropoietin (EPOR), thrombopoietin (THPO); or type II receptors including IFN-alpha, IFN- beta, IFN-gamma and multiple interleukins. Following ligand-binding to cell surface receptors [...] (1131 aa) |
| | ZDHHC9 | Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (364 aa) |
| | CDC42 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. In neurons, plays a role in the extension and maintenance of the formation of filopodia, thin and actin-rich surface projections (By similarity). Require [...] (197 aa) |
| | SRC | Tyrosine-protein kinase. (559 aa) |
| | MAP2K2 | Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa) |
| | FGFR1 | Fibroblast growth factor receptor. (820 aa) |
| | PAK1 | Non-specific serine/threonine protein kinase. (546 aa) |
| | FGFR4 | Fibroblast growth factor receptor. (903 aa) |
| | IL6ST | Interleukin 6 signal transducer. (938 aa) |
| | JAK3 | Tyrosine-protein kinase. (1103 aa) |
| | DUSP1 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (353 aa) |
| | DLG1 | Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (939 aa) |
| | SPNS1 | MFS domain-containing protein. (476 aa) |
| | PRKG2 | cGMP-dependent protein kinase. (762 aa) |
| | SPTBN4 | Spectrin beta, non-erythrocytic 4. (2617 aa) |
| | NRG3 | Neuregulin 3. (718 aa) |
| | DUSP16 | Dual specificity phosphatase 16. (664 aa) |
| | A0A286ZJU7_PIG | Uncharacterized protein; Belongs to the glycosyl hydrolase 1 family. (235 aa) |
| | DUSP4 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (436 aa) |
| | SPTBN1 | Spectrin beta chain; Belongs to the spectrin family. (2365 aa) |
| | GRIN2B | Glutamate ionotropic receptor NMDA type subunit 2B. (1484 aa) |
| | JAK1 | Tyrosine-protein kinase. (1154 aa) |
| | PSMD9 | PDZ domain-containing protein. (223 aa) |
| | RASAL2 | RAS protein activator like 2. (1279 aa) |
| | DUSP2 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (311 aa) |
| | LOC100626328 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (514 aa) |
| | PSMB3 | Proteasome subunit beta. (205 aa) |
| | ARRB1 | Arrestin beta 1. (607 aa) |
| | A0A286ZRB2_PIG | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (497 aa) |
| | A0A286ZS34_PIG | Uncharacterized protein. (179 aa) |
| | BRAP | BRCA1-associated protein. (592 aa) |
| | CDC14B | Uncharacterized protein. (542 aa) |
| | XPO1 | Exportin 1. (1071 aa) |
| | ACTB | Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (375 aa) |
| | BRAF | B-Raf proto-oncogene, serine/threonine kinase. (804 aa) |
| | TYK2 | Tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1226 aa) |
| | RAP1B | RAP1B, member of RAS oncogene family. (184 aa) |
| | APBB1IP | Amyloid beta precursor protein binding family B member 1 interacting protein. (688 aa) |
| | RASGRF2 | Ras protein specific guanine nucleotide releasing factor 2. (1270 aa) |
| | MARK3 | Non-specific serine/threonine protein kinase. (798 aa) |
| | SPTAN1 | Spectrin alpha, non-erythrocytic 1. (2390 aa) |
| | PSMD12 | 26S proteasome non-ATPase regulatory subunit 12 isoform 1. (456 aa) |
| | BTC | EGF-like domain-containing protein. (342 aa) |
| | KBTBD7 | Kelch repeat and BTB domain containing 7. (641 aa) |
| | SPTB | Spectrin beta chain; Belongs to the spectrin family. (2340 aa) |
| | DUSP8 | Dual specificity phosphatase 8. (625 aa) |
| | CUL3 | Cullin 3; Belongs to the cullin family. (773 aa) |
| | RASGEF1A | RasGEF domain family member 1A. (494 aa) |
| | RCE1 | Ras converting CAAX endopeptidase 1. (482 aa) |
| | SHOC2 | Leucine-rich repeat protein SHOC-2 isoform X1. (582 aa) |
| | FGF5 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (271 aa) |
| | ACTG1 | Actin gamma 1. (381 aa) |
| | TLN1 | Talin 1. (2558 aa) |
| | PEA15 | Proliferation and apoptosis adaptor protein 15. (157 aa) |
| | PDGFB | Platelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (240 aa) |
| | NRG1 | Neuregulin 1. (712 aa) |
| | PSMD7 | Proteasome 26S subunit, non-ATPase 7. (324 aa) |
| | FGF6 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | GDNF | Glial cell line-derived neurotrophic factor isoform 1. (211 aa) |
| | MAPK6 | Mitogen-activated protein kinase 6. (722 aa) |
| | CNKSR2 | Connector enhancer of kinase suppressor of Ras 2. (1050 aa) |
| | DUSP6 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (381 aa) |
| | CDK1 | Cyclin-dependent kinase 1 isoform 1; Belongs to the protein kinase superfamily. (297 aa) |
| | RASA3 | RAS p21 protein activator 3. (874 aa) |
| | PSME4 | Proteasome activator complex subunit 4. (1843 aa) |
| | NRAS | GTPase NRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. (189 aa) |
| | PTPN3 | Tyrosine-protein phosphatase non-receptor type; May act at junctions between the membrane and the cytoskeleton. (910 aa) |
| | SPRED3 | Sprouty related EVH1 domain containing 3. (452 aa) |
| | FGF23 | Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (243 aa) |
| | GFRA1 | GDNF family receptor alpha 1. (570 aa) |
| | PDGFRA | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1088 aa) |
| | LAMTOR3 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3. (124 aa) |
| | RPS27A | Ubiquitin-like domain-containing protein. (204 aa) |
| | CDC42EP5 | CDC42 effector protein 5. (153 aa) |
| | GRIN1 | Glutamate ionotropic receptor NMDA type subunit 1. (959 aa) |
| | DUSP9 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (382 aa) |
| | MAP3K11 | Mitogen-activated protein kinase kinase kinase. (858 aa) |
| | PPP1CB | Serine/threonine-protein phosphatase PP1-beta catalytic subunit; Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase (PP1) is essential for cell division, it participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progressi [...] (389 aa) |
| | DUSP5 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (384 aa) |
| | SPTBN2 | Spectrin beta chain; Belongs to the spectrin family. (2423 aa) |
| | RAP1A | RAP1A, member of RAS oncogene family. (184 aa) |
| | PPP2R5E | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (477 aa) |
| | HRAS | HRas proto-oncogene, GTPase. (189 aa) |
| | FGF19 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (219 aa) |
| | PSMC4 | Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa) |
| | RBX1 | E3 ubiquitin-protein ligase RBX1. (108 aa) |
| | PSMD8 | 26S proteasome non-ATPase regulatory subunit 8. (351 aa) |
| | RASGRP3 | RAS guanyl releasing protein 3. (692 aa) |
| | IRS2 | Insulin receptor substrate 2. (1092 aa) |
| | ARTN | Artemin. (227 aa) |
| | MAPK12 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (386 aa) |
| | PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform X1; Belongs to the PI3/PI4-kinase family. (1070 aa) |
| | PTPRA | Protein tyrosine phosphatase receptor type A. (850 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | FRS2 | Fibroblast growth factor receptor substrate 2. (550 aa) |
| | CAMK2G | Calcium/calmodulin dependent protein kinase II gamma. (595 aa) |
| | NRTN | Neurturin. (197 aa) |
| | CSF2RA | Fibronectin type-III domain-containing protein. (446 aa) |
| | PSMC6 | Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (481 aa) |
| | SHC3 | SHC adaptor protein 3. (656 aa) |
| | FGF2 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (316 aa) |
| | A0A287BGM8_PIG | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (494 aa) |
| | PPP2R5D | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (614 aa) |
| | FGF22 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (170 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (361 aa) |
| | PSMD14 | 26S proteasome non-ATPase regulatory subunit 14. (310 aa) |
| | PSMB1 | Proteasome subunit beta. (241 aa) |
| | YWHAB | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (264 aa) |
| | SYNGAP1 | Synaptic Ras GTPase activating protein 1. (1293 aa) |
| | SHC2 | Uncharacterized protein. (623 aa) |
| | PSMB10 | Proteasome subunit beta. (296 aa) |
| | PSMA7 | Proteasome subunit alpha type. (267 aa) |
| | PSMD10 | Proteasome 26S subunit, non-ATPase 10. (226 aa) |
| | LYPLA1 | Lysophospholipase 1. (303 aa) |
| | HBEGF | Proheparin-binding EGF-like growth factor; Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor (By similarity). (276 aa) |
| | PPP1CC | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (369 aa) |
| | RASA1 | RAS p21 protein activator 1. (1040 aa) |
| | FGF9 | Fibroblast growth factor 9; Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. May have a role in glial cell growth and differentiation during development, gliosis during repair and regeneration of brain tissue after damage, differentiation and survival of neuronal cells, and growth stimulation of glial tumors (By similarity). (228 aa) |
| | PIK3R2 | Uncharacterized protein. (772 aa) |
| | ARRB2 | Arrestin beta 2. (493 aa) |
| | CCND3 | Cyclin D3; Belongs to the cyclin family. (331 aa) |
| | IRS1 | Insulin receptor substrate 1. (1241 aa) |
| | LRRC7 | Leucine rich repeat containing 7. (1574 aa) |
| | PSMA1 | Proteasome subunit alpha type. (269 aa) |
| | PSMD5 | 26S proteasome non-ATPase regulatory subunit 5 isoform 1. (504 aa) |
| | CAMK2B | Calcium/calmodulin dependent protein kinase II beta. (670 aa) |
| | RGL1 | Ral guanine nucleotide dissociation stimulator-like 1 isoform 3. (875 aa) |
| | MRAS | Muscle RAS oncogene homolog. (210 aa) |
| | RAC1 | Rac family small GTPase 1. (186 aa) |
| | UBC | Ubiquitin-related; [Ubiquitin]: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repa [...] (837 aa) |
| | PSMA2 | Proteasome endopeptidase complex. (243 aa) |
| | PTPN11 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa) |
| | PSMC5 | 26S proteasome regulatory subunit 8; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC5 belongs to the heterohexameric ring of AAA (ATPases associated with [...] (435 aa) |
| | ACTN2 | Uncharacterized protein. (933 aa) |
| | PSMA4 | Proteasome subunit alpha type. (281 aa) |
| | LOC110258488 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (514 aa) |
| | PSMB2 | Proteasome subunit beta. (201 aa) |
| | PSMA3 | Proteasome subunit alpha type. (275 aa) |
| | PSMD13 | Proteasome 26S subunit, non-ATPase 13. (419 aa) |
| | FGF8 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa) |
| | SPTA1 | Spectrin alpha, erythrocytic 1. (2417 aa) |
| | EREG | Epiregulin. (168 aa) |
| | PSMC3 | Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (629 aa) |
| | NRG2 | Neuregulin 2. (858 aa) |
| | PPP2R5C | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (659 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1205 aa) |
| | SEPTIN7 | Septin 7; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (437 aa) |
| | SPRED1 | Sprouty related EVH1 domain containing 1. (445 aa) |
| | PSMB6 | Uncharacterized protein. (334 aa) |
| | GFRA4 | Uncharacterized protein. (367 aa) |
| | RGL3 | Ral guanine nucleotide dissociation stimulator like 3. (711 aa) |
| | PSME3 | Proteasome activator complex subunit 3; Subunit of the 11S REG-gamma (also called PA28-gamma) proteasome regulator, a doughnut-shaped homoheptamer which associates with the proteasome. 11S REG-gamma activates the trypsin-like catalytic subunit of the proteasome but inhibits the chymotrypsin-like and postglutamyl-preferring (PGPH) subunits. Facilitates the MDM2-p53/TP53 interaction which promotes ubiquitination- and MDM2-dependent proteasomal degradation of p53/TP53, limiting its accumulation and resulting in inhibited apoptosis after DNA damage. May also be involved in cell cycle regul [...] (265 aa) |
| | CAMK2D | Calcium/calmodulin-dependent protein kinase type II subunit delta; Calcium/calmodulin-dependent protein kinase involved in the regulation of Ca(2+) homeostatis and excitation-contraction coupling (ECC) in heart by targeting ion channels, transporters and accessory proteins involved in Ca(2+) influx into the myocyte, Ca(2+) release from the sarcoplasmic reticulum (SR), SR Ca(2+) uptake and Na(+) and K(+) channel transport. Targets also transcription factors and signaling molecules to regulate heart function. In its activated form, is involved in the pathogenesis of dilated cardiomyopath [...] (532 aa) |
| | ITGB3 | Integrin beta; Belongs to the integrin beta chain family. (835 aa) |
| | RASA2 | RAS p21 protein activator 2. (854 aa) |
| | DLG4 | Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. (764 aa) |
| | CDC42EP3 | CDC42 effector protein 3. (254 aa) |
| | PPP2CB | Serine/threonine-protein phosphatase. (476 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (568 aa) |
| | RALGDS | Uncharacterized protein. (938 aa) |
